A5090089063- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Stress Responses and Cortisol
- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Retinal and Optic Conditions
- Obesity, Physical Activity, Diet
- Eating Disorders and Behaviors
- Tryptophan and brain disorders
- Sleep and related disorders
- Biomarkers in Disease Mechanisms
- Pregnancy and preeclampsia studies
- Creativity in Education and Neuroscience
- Cardiac Structural Anomalies and Repair
- Neuroinflammation and Neurodegeneration Mechanisms
- Angiogenesis and VEGF in Cancer
- Tuberous Sclerosis Complex Research
- Vascular Tumors and Angiosarcomas
- Mesenchymal stem cell research
- Vascular Malformations and Hemangiomas
- Ophthalmology and Visual Impairment Studies
- Pulmonary Hypertension Research and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Tissue Engineering and Regenerative Medicine
Loma Linda University
2023-2025
Bridge University
2024
Miami Transplant Institute
2014
University of Miami
2013
Stem Cell Institute
2013
Whether culture-expanded mesenchymal stem cells or whole bone marrow mononuclear are safe and effective in chronic ischemic cardiomyopathy is controversial.To demonstrate the safety of transendocardial cell injection with autologous (MSCs) (BMCs) patients cardiomyopathy.A phase 1 2 randomized, blinded, placebo-controlled study involving 65 left ventricular (LV) ejection fraction less than 50% (September 1, 2009-July 12, 2013). The compared MSCs (n=19) placebo (n = 11) BMCs 19) 10), year...
Abstract Introduction Chronic adolescent stress profoundly affects prefrontal cortical networks regulating top‐down behavior control. However, the neurobiological pathways contributing to stress‐induced alterations in brain and remain largely unknown. influences growth factors immune responses, which may, turn, disrupt maturation function of networks. The tumor necrosis factor alpha‐converting enzyme/a disintegrin metalloproteinase 17 (TACE/ADAM17) is a sheddase with essential functions...
Binge eating (BE) is a highly pervasive maladaptive coping strategy in response to severe early life stress such as emotional and social neglect. BE described repeated episodes of uncontrolled tightly linked with comorbid mental health concerns. Despite stressors occurring at young age, the onset typically does not occur until adulthood providing an interval for potential therapeutic intervention. Currently, our knowledge longitudinal noninvasive digital biomarkers predictive needs further...
Early social isolation (SI) stress can negatively impact sleep habits and weight management throughout life. Strong evidence from studies in both humans rodents indicates that SI impacts increases the preference for high-fat calorically dense foods. These effects are significant risk factors associated with obesity. However, whether SI-induced shifts predict eating later life has not been evaluated. Furthermore, utilizing home-cage monitoring systems software capable of unbiasedly tracking...
Binge eating (BE) is a highly pervasive maladaptive coping strategy in response to severe early life stress such as emotional and social neglect. BE described repeated episodes of uncontrolled tightly linked with comorbid mental health concerns. Despite stressors occurring at young age, the onset typically does not occur until adulthood providing an interval for potential therapeutic intervention. Currently, our knowledge longitudinal noninvasive digital biomarkers predictive needs further...
Childhood obesity is a multifactorial disease affecting more than 160 million adolescents worldwide. Adolescent exposure to obesogenic environments, characterized by access high-fat diets and stress, precipitates maladaptive eating habits in adulthood such as binge eating. Evidence suggests strong association between Western-like high-saturated-fat (WD) food consumption dysregulated hormone fluctuations. However, few studies have explored the long-term impact of adolescent WD psychosocial...
Pregnancy at high altitude (> 2500 meters) reduces oxygenation to the fetus (i.e., gestational hypoxia). The low causes abnormal fetal lung development, with pulmonary arteries becoming thicker and dysfunctional. Associated these structural functional aberrations there is an increased risk of hypertension, intractable disease that increases infant mortality. Our previous work using a high-altitude sheep model shows has vascular remodeling, heart dysfunction, endoplasmic reticulum stress,...