A5070578465- Global Cancer Incidence and Screening
- Cancer Cells and Metastasis
- Breast Cancer Treatment Studies
- Urological Disorders and Treatments
- Advances in Oncology and Radiotherapy
- Global Health and Surgery
- BRCA gene mutations in cancer
- Gastrointestinal disorders and treatments
- Cancer Risks and Factors
- Economic and Financial Impacts of Cancer
- Cancer Genomics and Diagnostics
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- Genital Health and Disease
University of Cape Coast
2020-2025
Abstract Introduction: Triple negative breast cancer (TNBC) among women with African ancestry has been shown to be more prevalent than in of European ancestry. However, the root cause for this disparity is not fully understood. We have previously that gene expression stem cells TNBC tumors differs based on Western sub-Saharan Tumor organoids are three-dimensional structures derived from tumor and able mimic organization function organ origin. Organoids are, therefore, valuable tools studying...
Abstract Background: Triple negative breast cancer (TNBC) is most prevalent in women with Western sub-Saharan African ancestry, including Americans (AAs) and continental women. This similarity risk has been shown to be due part the shared genetic ancestry resulting from trans-Atlantic slave trade. To understand role of tumor biology TNBC AAs, we established a research collaboration Ghana (West African, WA), Precision Medicine for Aggressive Breast Cancers (PMABC), access WA female patients...
Abstract Introduction: Globally, the risk of death from cancer is higher in lower to middle income countries despite a reported incidence these countries. This attributed not only biological factors, but limited access resources for screening, diagnosis, and treatment. We conducted scoping review identify barriers diagnosis treatment among women low- low-middle-income countries, focusing on breast, colorectal, lung, cervix uteri, thyroid, corpus stomach cancers. Methods: Using Joanna Briggs...
Abstract Background: The prevalence of triple negative breast cancer (TNBC) in sub-Saharan Africa has been inconsistently reported, with some studies Ghana citing rates as high 80%. discrepancies TNBC have partly attributed to poor tissue handling during the pre- analytic phase, and lack 10% neutral buffered formalin for proper fixation. With a higher proportion TNBCs being many women are not candidates targeted therapy. This study evaluates impact improved pre-analytic on diagnostic outcome...
Breast cancer is the commonest diagnosed globally and second leading cause of cancer-related mortality among women younger than 40 years. This study comparatively reviewed demographic, pathologic molecular features Early-Onset Cancer (EOBC) reported in Ghana relation to Late Onset (LOBC).A descriptive, cross-sectional design was used, with purposive sampling retrospective histopathology data from 2019 2021. Reports core or incision biopsy, Wide Local Excision Mastectomy without axillary...
Abstract Upper GI bleeding from GIST is rare in Africa. The C‐kit‐negative variant uncommon worldwide. We report a case of 42‐year‐old woman managed for upper secondary to stomach GIST, negative CD117 but positive DOG 1 and CD 34. 1‐year postsurgery review uneventful.
Abstract Introduction Triple negative breast cancer (TNBC) among women with African ancestry has been shown to be more aggressive than in of European ancestry. However, the root cause for this disparity is not fully understood. In our previous studies, we show that gene expression stem cells TNBC tumors was differential based on Western sub-Saharan To study role biology TNBC, have developed patient-derived organoids (PDO) from (Ghanaian) and American will available research. Organoid culture...
Aims: The management of cut throat injuries with genital self-mutilation is very challenging due to the complex anatomy neck and need attain acceptable cosmetic functional outcomes penile reconstruction. This report thus seeks highlight importance a multidisciplinary approach these cases raise awareness for early suspicion diagnosis mental diseases especially among young people.
 Presentation Case: We present an 18-year old newly diagnosed paranoid schizophrenic man who presented penis...
Abstract Background: Breast cancer is the commonest diagnosed globally and second leading cause of cancer-related mortality among persons younger than 40 years. This study comparatively reviewed demographic, pathologic molecular features Early-Onset Cancer (EOBC) reported in Ghana relation to Late Onset (LOBC). Methods: A descriptive, cross-sectional design was used, with purposive sampling retrospective histopathology data from 2019 2021. Core/incision biopsy, mastectomy matched...