Abstract Surgical archives of tumor specimens are often impure. The presence RNA transcripts from nontumor cells, such as immune and stromal can impede analyses cancer expression profiles. To systematically analyze the impact purity, gene profiles purities were obtained for 7,794 across 21 types (available in Cancer Genome Atlas consortium). First, we observed that genes with roles immunity oxidative phosphorylation significantly inversely correlated respectively. implicated immunotherapy...

Understanding and promoting sport consumer well-being are essential for legitimizing in the policy sector building long-term relationships with consumers. To better understand relations between consumption (i.e., participation, spectating, media viewing) long- short-term subjective well-being, a study was conducted using ecological momentary assessment multilevel structural equation modeling. Need fulfillment (detachment-recovery, autonomy, achievement, belonging) also tested as key...

Highlights• Sport media consumption leads to improved well-being through need fulfillment.• Well-being improves hedonic eudaimonic fulfillment, if identified with the sport team.• social game is watched others.

This study posits that Fear of Missing Out (FOMO) can function as an extrinsic motive stimulating sport event consumption by inducing consumers to overcome leisure constraints. Also, FOMO-driven is proposed affect experience for being grounded on than intrinsic rewards. In Study 1, the moderation FOMO between intrapersonal and structural constraints media viewing intention are tested. 2, relations among consumption, rewards (i.e., enjoyment), social adherence), consumer satisfaction...

The role of volunteers is an important factor for the sustainability mega sports events. Key issues in literature on event are volunteer satisfaction and its determinants outcomes. Therefore, purpose current study was to investigate effects fulfillment volunteers’ psychological needs Volunteer Management Practices (VMP) overall satisfaction, test their conditional depending involvement. Additionally, present aimed examine future activity, word-of-mouth, host city visitation. For these...

Purpose The purpose of this study is to examine the role team-related cues and team identification in influencing visual attention engagement with corporate social marketing (CSM) messages on sport Twitter pages. Design/methodology/approach An experimental design was adopted using a 2 × factorial approach, two levels for each following factors: message framing (positive vs negative), (with without logos) (high low). Eye-tracking technology used identify cause promotion messages. data from...

This research examines the various ways that video games, particularly esports, have been leveraged for content production and fan engagement (i.e., gamification) in traditional sports during COVID-19 pandemic, as well fans’ reactions relation to their motives, points of attachment, other consumer behavior. The study presents a sports–gaming convergence framework identifies six popular gamification modes where games converge pandemic. survey results further reveal is not consumed simply...

Papillary thyroid carcinoma (PTC) is a heterogeneous tumor with various histological and molecular subtypes. EHD2 involved in endocytosis endosomal recycling. This study aimed to investigate the prognostic significance of expression PTC develop new model for predicting persistent/recurrent disease after thyroidectomy. Pathologic slides 512 consecutive patients ≥ 1 cm were retrospectively reviewed. BRAF mutation analysis immunohistochemistry performed. Clinical mRNA was analyzed 388 using The...

Abstract: From a tourism perspective, this study examined the change in host countries’ destination images before and after mega sporting events. The developed tested conceptual model delineating relationship among sport event involvement, designation images, attitude towards country, visit intention. This further if has same pattern across different For purpose of study, 2015 International Association Athletics Federations Championships 2014 Winter Olympic Games were selected. Using mall...

When it comes to the relationship between sport media consumption (SMC) and sporting event attendance, two contradicting notions have been dominant: symbiosis vs. competition. With a focus on consumers' hedonic need fulfillment psychological concept of flow experience, current study examined whether SMC stimulates spectatorship (symbiotic relationship). Specifically, we aimed examine impact personal factor (team identification) situational (perceived team performance) experience how drives...

Mutation hotspots are either solitary amino acid residues or stretches of acids that show elevated mutation frequency in cancer-related genes, but their prevalence and biological relevance not completely understood. Here, we developed a Smith-Waterman algorithm-based hotspot discovery method, MutClustSW, to identify single clustered residues. We identified 181 missense from COSMIC TCGA databases. In addition 77 residue (42.5 percent) including well-known such as IDH1 (p.R132) BRAF (p.V600),...

ABSTRACTABSTRACTThis study investigates how sport fans psychologically process and cope with the loss of one’s team is linked to temporal well-being. Grounded on need theory Lazarus’ model stress, unfulfillment introduced as a psychological threat derived from loss, which triggers coping strategies deal negative well-being effects associated loss. With two-wave survey-based natural field conducted identified NFL fans, relations among (of arousal, achievement social needs), (i.e., seeking...

In order to provide high-quality sport events and cultivate economic, social, environmental benefits in the local community, regional commissions US form partnerships with organizations across sectors. Building on Parent Harvey's partnership framework, this study seeks reveal components processes of collaboration between their partners delivery subsequent outcomes. Using purposive convenient sampling, data were collected from 12 in-depth interviews leaders partnering based accessibility...

The effects of behavioral addiction to video games has received increasing attention in the literature, given increased use intensity among subgroups game players.This study seeks empirically determine relationship between gaming and hedonic experience player.We conducted a survey 835 individuals who regularly play experience. We divided sample into quartiles by self-reported addictive symptom level (from Internet Gaming Disorder Scale) polynomial regressions separately for each quartile.We...

Abstract: While assessment of team-level marketing performance for a professional sport franchise is important both the team marketer and researcher to develop strategy understand performance, no evidence using full set teams long period time currently exists. We propose that can be estimated with stochastic frontier model. Using twenty seasons Major League Baseball (MLB) attendance data, we estimate (i.e., maximal reach) after controlling factors unrelated marketing, argue efficiency...

Hosting sport events is costly, but the positive impact of hosting has not been studied well. We consider promotion physical activity, known as trickle-down effect, to be a new dimension this kind impact. Using exogenous variations in and relegation Bundesliga 1, we test effect presence 1 club on local non-profit football membership. German city-level annual membership data from metropolitan Rhine-Ruhr, group cities with experience either or treatment other comparison group....

Widespread use of smartphones and wireless internet have made YouTube an easily accessible educational modality. Many residents to acquire knowledge regarding microsurgical techniques; however, its quality effect has not been verified. We included 22 working in the Department Plastic Reconstructive Surgery at our institute. Using block randomization, seven were allocated a textbook group (TG), eight free-searching (FSG), designated-video (DVG). After reviewing textbooks, videos, or...

Abstract: This study investigates soccer video games as a platform to promote engagement (i.e., involvement, behavioral intentions) among those who do not physically play regularly. Perceived literacy is proposed construct explaining the promotional effect, consisting of four sub-themes affective attitude, perceived functional knowledge, critical and competence. A was conducted based on an online survey with US Canadian adults regular basis. With structural equation modeling, (1) association...

Purpose: Vicarious achievement is tested as a source/channel for fulfilling needs and boosting life satisfaction through in-person sport spectating media viewing; factors influential on vicarious are examined.Method: Through ecological momentary assessment focusing college students, 2,746 responses from 242 respondents were collected. With multi- single-level SEM, the effects of viewing temporal mediation tested; performance identification level examined factors.Findings: Sport was an...

The dorsal metacarpal artery perforator flap is a that rises from the hand dorsum. Owing to its reliability and versatility, this used as workhorse for finger defect. However, cover radial-volar defect of proximal interphalangeal joint (PIPJ) index finger, longer required than before. Here, we introduce oblique extended reverse first (FDMA) aspect finger. A 45-year-old man got injured PIPJ left caused by thermal press machine. wound was 2 × 1 cm in size, bone were exposed. We FDMA...