A5073170810- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Cerebrovascular and Carotid Artery Diseases
- Neuroscience and Neuropharmacology Research
- Venous Thromboembolism Diagnosis and Management
- Epilepsy research and treatment
- Sulfur Compounds in Biology
- Neurotransmitter Receptor Influence on Behavior
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Sedative Agents
- Empathy and Medical Education
- Pharmacological Effects and Toxicity Studies
- Amyotrophic Lateral Sclerosis Research
- Mast cells and histamine
- Literature Analysis and Criticism
- Restraint-Related Deaths
- Advanced MRI Techniques and Applications
- Neurological and metabolic disorders
- 3D Surveying and Cultural Heritage
- Hallucinations in medical conditions
- Bipolar Disorder and Treatment
- Psychological Well-being and Life Satisfaction
- Receptor Mechanisms and Signaling
- Botulinum Toxin and Related Neurological Disorders
- Paranormal Experiences and Beliefs
University of Bologna
2023
University of Rome Tor Vergata
2011-2019
Istituto Tecnico Industriale Alessandro Volta
2018
Institut de Neurophysiopathologie
2015
Magna Graecia University
2007-2012
Fondazione Santa Lucia
2011
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease whose pathophysiological deficits, causing impairment in function, are largely unknown. Here we propose that hydrogen sulfide (H2 S), as glial-released inflammatory factor, contributes to ALS-mediated death.H2 S concentrations were analyzed the cerebrospinal fluid of 37 sporadic ALS patients and 14 age- gender-matched controls, tissues familial (fALS) mouse model, spinal cord culture media by means specific innovative...
Objectives To evaluate the safety and efficacy of endovascular therapy in elderly adults treated for acute ischemic stroke. Design Retrospective cohort study. Setting Comprehensive Stroke Center, University Tor Vergata, Rome, Italy. Participants Elderly stroke (N = 219). Measurements were divided into two groups based on their age (n 62, ≥80; n 157, <80). Baseline procedural characteristics, outcomes such as intracranial hemorrhage ( ICH ) mortality successful reperfusion 3‐month good...
Few data exist on malignant middle cerebral artery infarction (MMI) among patients with acute ischemic stroke (AIS) after endovascular treatment (ET). Numerous predictors of MMI evolution have been proposed, but a comprehensive research undergoing ET has never performed. Our purpose was to find practical model determine robust in ET.Patients from prospective single-center database AIS secondary large intracranial vessel occlusion the anterior circulation, treated ET, were retrospectively...
Objective: To report a case of visual hallucinations and psychomotor agitation probably induced by an interaction between venlafaxine propafenone. Case Summary: An 85-year-old woman was admitted for evaluation mood disorder on March 20, 2006. Her general practitioner had prescribed sertraline treatment, which started about 6 months earlier. The patient's medical history included hypertension, supraventricular tachycardia, chronic bronchitis, arthritis, she received ramipril, ticlopidine,...
Trace amines (TAs) are a class of endogenous compounds strictly related to classic monoamine neurotransmitters with regard their structure, metabolism, and tissue distribution. Although the presence TAs in mammalian brain has been recognized for decades, until recently they were considered be by-products amino acid metabolism or as "false" neurotransmitters. The discovery 2001 new family G-protein-coupled receptors (GPCRs), namely trace receptors, re-ignited interest TAs. In particular, two...
Background and purpose To report clinical procedural outcomes of acute ischemic stroke patients after endovascular treatment with the new thromboaspiration catheter AXS Catalyst 6. Methods Patients anterior posterior circulation were selected. Successful reperfusion defined as a Thrombolysis in Cerebral Infarction (TICI) score ≥2 b 3-month functional independence modified Rankin Scale (mRS) ≤2 main efficacy outcomes. Symptomatic intracranial hemorrhage mortality safety Results 107 suitable...
We have recently published a paper in Annals of Neurology entitled “Evidence Hydrogen Sulphide involvement Amyotrophic Lateral Sclerosis” [1] where we reported study performed patients, and genetic model familial ALS. The outcome this is an original finding: the overproduction hydrogen sulphide (H 2 S) human patients animal model. also show that H S produced, mainly, by glial cells, toxic to motor neurons increases significantly cytosolic Ca 2+ concentration. Altogether, our data introduce...
Background: Whether radiological factors influence the effect of time to recanalization on outcome in basilar artery occlusion (BAO) is uncertain. We evaluated association between onset treatment (OTT), prognostic (presence collaterals and extent occlusion) clinical endovascular BAO patients. Methods: Clinical data consecutive endovascular-treated stroke patients with diagnosed CT angiography at Royal Melbourne Hospital (Australia), Adelaide University Tor Vergata (Rome, Italy) from...
<sec> <title>BACKGROUND</title> A large body of research has documented the efficacy psychological interventions integrated with virtual reality (VR) therapies in treating psychiatric disorders. However, concept positive mental health calls for a 2-fold approach which both symptoms and functioning should be addressed by modern interventions. </sec> <title>OBJECTIVE</title> This review aimed to summarize studies that applied VR embracing perspective. <title>METHODS</title> literature search...