A5035940704- Liver Disease Diagnosis and Treatment
- Parasites and Host Interactions
- Macrophage Migration Inhibitory Factor
- Energy Harvesting in Wireless Networks
- Underwater Vehicles and Communication Systems
- Helicobacter pylori-related gastroenterology studies
- Biochemical Analysis and Sensing Techniques
- Underwater Acoustics Research
- Insect Pest Control Strategies
- Mosquito-borne diseases and control
- Peatlands and Wetlands Ecology
- Retinoids in leukemia and cellular processes
- Adipokines, Inflammation, and Metabolic Diseases
- Endoplasmic Reticulum Stress and Disease
- Antioxidant Activity and Oxidative Stress
- Berberine and alkaloids research
- Diet, Metabolism, and Disease
- Drug-Induced Ocular Toxicity
- Ion Channels and Receptors
- Marine and coastal ecosystems
- Lipid metabolism and disorders
- Research on Leishmaniasis Studies
- Malaria Research and Control
- Immune Cell Function and Interaction
- Adipose Tissue and Metabolism
Gansu Agricultural University
2025
Lanzhou Veterinary Research Institute
2025
Chinese Academy of Agricultural Sciences
2025
Nanjing Medical University
2020-2024
Southeast University
2024
Jinan University
2024
First Affiliated Hospital of Jinan University
2022-2024
Beijing Children’s Hospital
2024
Capital Medical University
2024
Nanjing Normal University
2024
Previous studies have indicated that indolepropionic acid (IPA), derived from dietary tryptophan via gut microbiota conversion, is negatively correlated with type 2 diabetes mellitus and systemic low-grade inflammation. However, the effects of IPA administration on obesity, as well underlying mechanisms, remain unclear. In present study, we observed obesity leads to a dramatic reduction in levels both serum colonic mucosa, supplementation exerted beneficial weight, glucose lipid metabolism...
Ficus hirta Vahl., a traditional Chinese medicine commonly used in the Lingnan region, has been extensively for liver disease treatment China. Its notable antioxidant and anti-inflammatory properties have reported previous studies. However, its potential effect underlying mechanism on fibrosis remains unclear.
Nonalcoholic fatty liver disease (NAFLD) has gradually become one of the most serious diseases threatening human health in world. Currently, Chinese herbal medicine is a potentially important treatment option for NAFLD, and development effective good prospect. Previous studies have suggested that Ficus hirta Vahl. (FV) various protective effects on liver. In this study, we investigated therapeutic outcomes FV its underlying mechanism using HepG2 cell lines induced by palmitate (PA) mouse...
In this paper, a quasi-deterministic (Q-D) model for non-stationary underwater acoustic (UWA) channels is proposed. This combines the BELLHOP deterministic and geometry-based stochastic (GBSM), which provides higher accuracy flexibility. Different propagation components in shallow water are classified as D-rays, R-rays F-rays proposed model, where D-rays modeled by while both GBSM. Some important channel statistical properties, including time-frequency correlation function (TF-CF), Doppler...
Camels, with the ability to survive under drought and chronic hunger, developed exceptional efficient lipid reserves energy substance metabolic characteristics. Fibroblast growth factor (FGF) 21 is a hormone that regulates important pathways homeostasis. However, absence of specific detection method for camel FGF21 impacts research on camels' regulation. This study established direct competition ELISA assay detecting FGF21. Camel antigen was expressed purified through prokaryotic expression...
Regulatory T cells (Tregs) can alleviate the development of autoimmune and inflammatory diseases, thereby proposing their role as a new therapeutic strategy. Parasitic helminths have co-evolved with hosts to generate immunological privilege immune tolerance through inducing Tregs. Thus, constructing "Tregs-induction"-based discovery pipeline from parasitic helminth is promising strategy control diseases.The gel filtration chromatography reverse-phase high-performance liquid (RP-HPLC) were...
Background and Aims The heat shock protein (Hsp) 90α is induced by stress regulates inflammation through multiple pathways. Elevated serum Hsp90α had been found in nonalcoholic steatohepatitis (NASH). Geranylgeranylacetone (GGA, also called teprenone) a terpenoid derivative. It was reported to induce Hsp alleviate insulin resistance. We aimed evaluate the as biomarker predicting metabolic-associated fatty liver disease (MAFLD) define therapeutic effects of geranylgeranylacetone for disease....
Abstract Background Hepatic granuloma formation and fibrosis as the consequence of tissue entrapped eggs produced by female schistosomes characterize pathology Schistosoma japonicum infection. It has been proposed that fucoidan, a sulfated polysaccharide existing naturally in brown seaweed Fucus vesiculosus , plays diversified role to perform immunomodulatory activities. However, whether fucoidan functions host hepatic is unknown identifying potential mechanism responsible for improvement...
Obesity-induced adipose tissue dysfunction and disorders of glycolipid metabolism have become a worldwide research priority. Zfp217 plays crucial role in adipogenesis 3T3-L1 preadipocytes, but about its functions animal models are not yet clear. To explore the high-fat diet (HFD)-induced obese mice, global heterozygous knockout (Zfp217+/−) mice were constructed. Zfp217+/− Zfp217+/+ fed normal chow (NC) did differ significantly weight gain, percent body fat mass, glucose tolerance, or insulin...
Radix Fici Hirtae (RFH), known as Cantonese ginseng, is an alternative folk medicine that widely used to treat various diseases in southern China. The aim of this study was investigate the effect and metabolic mechanisms pretreatment with RFH on serum profiles carbon tetrachloride (CCl4) induced acute liver injury mice.Mice fed water extract at a dose 1.5 g/kg 0.75 for consecutive 7 days, then samples were taken metabolomic analysis. Furthermore, bioinformatics pathways analysis measured.The...
Mosquitoes, as temperature-sensitive ectothermic vectors, exhibit temperature-dependent traits like reproduction and survival. This study investigates Culex pallens (Cx. pallens) mosquito responses to abrupt temperature increases their implications for control programs. Cx. first instar larvae (24hr post hatching) newly enclosed adults emergence) were separately exposed heat shock regimes of 33℃, 37℃, 42℃ 3 days alongside a 27℃. Results showed that mortality was triggered at within day....