A5077526392- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Malaria Research and Control
- SARS-CoV-2 detection and testing
- Global Maternal and Child Health
- Viral gastroenteritis research and epidemiology
- Potassium and Related Disorders
- Mosquito-borne diseases and control
- COVID-19 and Mental Health
- Escherichia coli research studies
- Infant Nutrition and Health
- Clostridium difficile and Clostridium perfringens research
- Vaccine Coverage and Hesitancy
- Hemoglobinopathies and Related Disorders
- Respiratory viral infections research
- Intensive Care Unit Cognitive Disorders
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Human Health and Disease
- Exercise and Physiological Responses
- Liver Disease Diagnosis and Treatment
- Infection Control in Healthcare
- Influenza Virus Research Studies
University of Maryland, Baltimore
2017-2025
Uniformed Services University of the Health Sciences
2021-2024
Henry M. Jackson Foundation
2022-2024
Johns Hopkins University
2022
Engineering Associates (United States)
2017
Background Chronic neuropsychological sequelae following SARS-CoV-2 infection, including depression, anxiety, fatigue, and general cognitive difficulties, are a major public health concern. Given the potential impact of long-term impairment, it is important to characterize frequency predictors this post-infection phenotype. Methods The Epidemiology, Immunology, Clinical Characteristics Emerging Infectious Diseases with Pandemic Potential (EPICC) study longitudinal assessing infection in U.S....
Abstract While sulfadoxine-pyrimethamine has been the primary drug in intermittent preventive treatment pregnancy, dihydroartemisinin-piperaquine (DP) is being considered as an alternative. DP may lead to lower antimalarial antibodies mother, resulting higher risk of malaria infancy. We probed cord blood sera collected from women enrolled a clinical trial vs on protein microarray containing diverse Plasmodium falciparum erythrocyte membrane proteins 1 measure impact pregnancy associated with...
is the second leading cause of diarrheal diseases, accounting for >200,000 infections and >50,000 deaths in children under 5 years age annually worldwide. The incidence
Distribution campaigns for insecticide-treated nets (ITN) have increased the use of ITNs in Malawi, but malaria prevalence remains high even among those using nets. Previous studies addressed ITN ownership, insecticide resistance, and frequency as possible contributing factors to infection despite coverage, rarely considered whether condition ITN, or how many people it, impacts efficacy. This study assessed integrity, age, number persons sharing a net might mitigate reduce protective...
Patient-reported outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are an important measure the full burden disease (COVID). Here, we examine how (1) infecting genotype and COVID-19 vaccination correlate with inFLUenza Patient-Reported Outcome (FLU-PRO) Plus score, including by symptom domains, (2) FLU-PRO scores predict return to usual activities health.The epidemiology, immunology, clinical characteristics pandemic infectious diseases (EPICC) study was...
Patient's gender may impact pharmacokinetics and play a role in viral suppression. Existing literature has focused on treatment-naïve patients produced inconclusive results, often implicating differences adherence as the driver of gender-based outcome differences. The present analysis assessed whether suppression third-line HIV treatment among closely followed population differs by gender. A retrospective cohort study was initiated at Advanced Treatment Centre Lusaka, Zambia between January...
Abstract Background Intermittent preventive treatment of malaria during pregnancy (IPTp) with dihydroartemisinin-piperaquine (DP) provides greater protection from placental than sulfadoxine-pyrimethamine (SP). Some studies suggest alters risk infection in infants, but few have quantified the effect IPTp on infant susceptibility to malaria. Methods Infants born women enrolled a randomized clinical trial comparing IPTp-SP and IPTp-DP Malawi were followed birth 24 months assess time first...
An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.
Abstract Background Infants under 6 months of age are often excluded from malaria surveillance and observational studies. The impact during early infancy on health later in childhood remains unknown. Methods two birth cohorts Malawi were monitored at quarterly intervals whenever they ill through 24 for Plasmodium falciparum infections clinical malaria. Poisson regression linear mixed effects models measured the effect exposure to subsequent incidence, weight-for-age z-scores (WAZ),...
Abstract Shigella is the second leading cause of diarrheal diseases, accounting for >200,000 infections and >50,000 deaths in children under 5 years age annually worldwide. The incidence -induced diarrhea relatively low during first year life increases substantially, reaching its peak between 11 to 24 months age. This epidemiological trend hints at an early protective immunity maternal origin increase disease when maternally acquired wanes. magnitude, type, antigenic diversity,...
Abstract Background SARS-CoV-2 infections have been associated with self-reported impaired cognitive function, but research examining objective assessments is scant. Given the potential impact of long-term impairment, it important to characterize this post-infection phenotype. Methods The Epidemiology, Immunology, and Clinical Characteristics Emerging Infectious Diseases Pandemic Potential (EPICC) study a longitudinal cohort assessing infection in Military Health System (MHS) beneficiaries....
Abstract Background Congregate military populations remain at risk of SARS-CoV-2 outbreaks and the optimal surveillance approach in such settings remains unclear. We enrolled midshipmen United States Naval Academy (USNA) a setting frequent PCR screening use prevention strategies. Methods Dried blood spots (DBS) saliva were collected August 2020, December February 2021 (saliva only) April/May to measure anti-SARS-CoV-2 spike (S) nucleoprotein (NP) IgG. COVID-19 vaccine history records tests...
Abstract The optimal approach to COVID-19 surveillance in congregate populations remains unclear. Our study at the US Naval Academy Annapolis, Maryland, USA, assessed concordance of antibody prevalence longitudinally collected dried blood spots and saliva a setting frequent PCR-based testing. findings highlight utility salivary-based surveillance.