A5101459606- Herpesvirus Infections and Treatments
- Poxvirus research and outbreaks
- Climate Change and Health Impacts
- Plant Virus Research Studies
- Pesticide Residue Analysis and Safety
- Protein Interaction Studies and Fluorescence Analysis
- COVID-19 epidemiological studies
- Global Health Care Issues
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- Chemical Synthesis and Analysis
- Phytochemicals and Medicinal Plants
- Health disparities and outcomes
- Food Chemistry and Fat Analysis
- Viral Infections and Outbreaks Research
- Forensic Toxicology and Drug Analysis
- Radiopharmaceutical Chemistry and Applications
- Economic Sanctions and International Relations
- Analytical Methods in Pharmaceuticals
- Sensory Analysis and Statistical Methods
- Virus-based gene therapy research
- Chemical Reactions and Isotopes
- Anesthesia and Neurotoxicity Research
- Geophysics and Gravity Measurements
- Pharmaceutical Quality and Counterfeiting
Amity University
2023-2025
Heidelberg University
2024
Institute of Forensic Science
2024
Umeå University
2023
University of Illinois Urbana-Champaign
2000-2005
Abstract Tetramethrin (TMT) is a commonly used insecticide and has carcinogenic neurodegenerative effect on humans. The binding mechanism toxicological implications of TMT to human serum albumin (HSA) were examined in this study employing combination biophysical computational methods indicating moderate affinity potential hepato renal toxicity. Fluorescence quenching experiments showed that binds HSA with affinity, the process was spontaneous predominantly enthalpy‐driven. Circular dichroism...
ABSTRACT Nine field strains of fowlpox virus (FPV) isolated during a 24-year span from geographically diverse outbreaks in the United States were screened for presence reticuloendotheliosis (REV) sequences their genomes by PCR. Each isolate appeared to be heterogeneous that either nearly intact provirus or just 248- 508-nucleotide fusion portions integrated REV 5′ and 3′ long terminal repeats (LTRs) was exclusively present at same genomic site. In contrast, four vaccines FPV origin three...
This study presents an analytical method for detection and identification of pesticides in simulated biological matrices, i.e., gastric fluid (SGF) urine sample (SUS). The approach combines the QuEChERS (quick, easy, cheap, effective, rugged safe) preparation technique with ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) pesticide analysis. A modified extraction protocol was developed to enhance recovery, improving both accuracy reproducibility quantification...
Fowlpox virus (FWPV) has been isolated from vaccinated chicken flocks during subsequent fowlpox outbreaks that were characterized by a high degree of mortality and significant economic losses. This inability current vaccines to induce adequate immunity in poultry could be reflective an antigenic and/or biologic distinctiveness FWPV field isolates. In this regard, whereas infectious reticuloendotheliosis (REV) provirus is present the majority viruses' genomes, only remnants REV long terminal...
Vaccines for the prevention of fowl pox in chickens and turkeys have been available more than five decades. However, recent years outbreaks occurred several previously vaccinated chicken flocks. Presumably, poxviruses (FPVs) antigenically different from attenuated vaccine strains are responsible such occurrences. In support this concept, we detected minor antigenic changes field isolates based on comparative immunoblotting with polyclonal anti-FPV serum. Realizing need antibodies specific...
In the present study, Liquid chromatography was Coupled with tandem mass spectrometry (LC-MS/MS) coupled QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe). The development of an analytical technique based on dispersive solid phase extraction (dSPE) has opted for simultaneous detection fluoxetine sertraline hydrochloride at six distinct concentrations in simulated gastric fluid. antidepressants were identified quantified using (ESI+) mode. With limits (LOD) quantification (LOQ) 9.42...
Temperature influences the transmission of mosquito-borne pathogens with significant implications for disease risk in context climate change. Mathematical models infections rely on functions that capture mosquito-pathogen interactions response to temperature better estimate dynamics. To derive these functions, experimental studies provide valuable data sensitivity mosquito life-history traits and pathogen transmission. However, scarcity inconsistencies methodologies analysing comparing...
This review article explores the role of herbal bioenhancers in improving drug bioavailability, a crucial factor for therapeutic efficacy. Drug bioavailability is often limited by poor solubility, low membrane permeability, and metabolic degradation. Traditional modern approaches have developed various methods to address these barriers, including use bioenhancers, which naturally augment absorption effects drugs without producing pharmacological themselves. Key include piperine, curcumin,...
Pesticides are commonly used in agriculture to control pests and improve crop yields, but they pose significant risks human health the environment due potential residues biological matrices. This study presents an innovative ultrasonicator-aided cartridge-based extraction method specifically designed for detecting pesticides simulated samples, utilizing ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). To address need reliable analytical techniques forensic...
Abstract Reaction of Ph3P[dbnd]NSiMe3 with NH4ReO4 produced the ion pair Ph3P[dbnd]NH2 +ReO4- which was characterized by spectroscopic data and X-ray crystallography. The thermolysis this gave neutral Re(VII) complex: Ph3P[dbnd]N-ReO3 in good yields. reactions 99mTcO4- or 188ReO4- Ph3P[dbnd]N-SiMe3 also metallic radioisotope analogues pair: Ph3P[dbnd]NH2+MO4- (M = 99mTc 188Re) on heating produce species Ph3P[dbnd]N-MO3 188Re). implications such small molecule 188Re complexes for development...