- Mosquito-borne diseases and control
- Climate Change and Health Impacts
- Malaria Research and Control
- Global Maternal and Child Health
- Air Quality and Health Impacts
- Global Health Care Issues
- COVID-19 epidemiological studies
- Child Nutrition and Water Access
- Viral Infections and Vectors
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Poverty, Education, and Child Welfare
- Zoonotic diseases and public health
- Adolescent Sexual and Reproductive Health
- Global Public Health Policies and Epidemiology
- Travel-related health issues
- HIV/AIDS Impact and Responses
- HIV-related health complications and treatments
- Viral Infections and Outbreaks Research
- Antibiotic Use and Resistance
- Data-Driven Disease Surveillance
- Species Distribution and Climate Change
- Agricultural risk and resilience
- Medical Coding and Health Information
- Livestock and Poultry Management
Umeå University
2016-2025
Heidelberg University
2023-2025
University Hospital Heidelberg
2023-2025
Kenya Medical Research Institute
2011-2023
Centre for Global Health Research
2022
New York University
2019
European Centre for Disease Prevention and Control
2019
Centers for Disease Control and Prevention
2012-2016
Great Lakes University of Kisumu
2014
Indepth Network
2014
BackgroundMosquito-borne diseases are expanding their range, and re-emerging in areas where they had subsided for decades. The extent to which climate change influences the transmission suitability population at risk of mosquito-borne across different altitudes densities has not been investigated. aim this study was quantify will influence length season estimate future, given an altitudinal gradient.MethodsUsing a multi-model multi-scenario framework, we estimated changes global malaria...
The KEMRI/Centers for Disease Control and Prevention (CDC) Health Demographic Surveillance System (HDSS) is located in Rarieda, Siaya Gem Districts (Siaya County), lying northeast of Lake Victoria Nyanza Province, western Kenya. KEMRI/CDC HDSS, with approximately 220 000 inhabitants, has been the foundation a variety studies, including evaluations insecticide-treated bed nets, burden diarrhoeal disease tuberculosis, malaria parasitaemia anaemia, treatment strategies immunological correlates...
Background:Aedes aegypti is the principal vector for several important arbovirus diseases, including dengue, chikungunya, yellow fever, and Zika. While recent empirical research has attempted to identify current global distribution of vector, seasonal, longer-term dynamics mosquito in response trends climate, population, economic development over twentieth twenty-first century remains be elucidated. Methods: In this study, we use a process-based mathematical model estimate abundance. The...
Background: The rollout of antiretroviral therapy (ART) is one the largest public health interventions in Eastern and Southern Africa recent years. Its impact well described clinical cohort studies, but population-based evidence rare. Methods: We use data from seven demographic surveillance sites that also conduct community-based HIV testing collect information on uptake services. present crude death rates adults (aged 15–64) for period 2000–2011 by sex, status, treatment status. Parametric...
Climate change allows Aedes aegypti to infest new areas. Consequently, it enables the arboviruses mosquito transmits -- e.g., dengue, chikungunya, Zika and yellow fever - emerge in previously uninfected An example is Portuguese island of Madeira during 2012-13.We aim understand how climate will affect future spread this potent vector, as an aid assessing risk disease outbreaks effectively allocating resources for vector control.We used empirically-informed, process-based mathematical model...
In Europe, the frequency, intensity, and geographic range of West Nile virus (WNV)-outbreaks have increased over past decade, with a 7.2-fold increase in 2018 compared to 2017, markedly expanded area 2010. The reasons for this expansion remain largely unknown due complexity transmission pathways underlying disease drivers. first, we use advanced artificial intelligence disentangle contribution eco-climatic drivers WNV-outbreaks across Europe using decade-long (2010-2019) data at high spatial...
West Nile virus (WNV), a mosquito-borne zoonosis, has emerged as disease of public health concern in Europe. Recent outbreaks have been attributed to suitable climatic conditions for its vectors favoring transmission. However, date, projections the risk WNV expansion under climate change scenarios is lacking. Here, we estimate WNV-outbreaks set and socioeconomic scenarios. We delineate potential risk-areas growth population at (PAR). used supervised machine learning classifier, XGBoost,...
We report and explore changes in child mortality a rural area of Kenya during 2003-2009, when major public health interventions were scaled-up. Mortality ratios rates calculated by using the Medical Research Institute/Centers for Disease Control Prevention Demographic Surveillance System. Inpatient outpatient morbidity mortality, verbal autopsy data analyzed. children less than five years age decreased from 241 to 137 deaths/1,000 live-births 2003 2007 respectively. In 2008, they increased...
Background Dengue outbreaks are increasing in frequency over space and time, affecting people's health burdening resource-constrained systems. The ability to detect early emerging is key mounting an effective response. warning response system (EWARS) a toolkit that provides countries with early-warning systems for efficient cost-effective local responses. EWARS uses outbreak alarm indicators derive prediction models can be used prospectively predict forthcoming dengue at district level....
Extreme weather is becoming more common due to climate change and threatens human health through climate-sensitive diseases, with very uneven effects around the globe. Low-income, rural populations in Sahel region of west Africa are projected be severely affected by change. Climate-sensitive disease burdens have been linked conditions areas Sahel, although comprehensive, disease-specific empirical evidence on these relationships scarce. In this study, we aim provide an analysis associations...
The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA Network, http://alpha.lshtm.ac.uk/) brings together ten population-based HIV surveillance sites in eastern and southern Africa, is coordinated by the London School of Hygiene Tropical Medicine (LSHTM).It was established 2005 aims to (i) broaden evidence base epidemiology informing policy, (ii) strengthen analytical capacity research, (iii) foster collaboration between network members.All study sites, some...
Background Malaria is an important cause of morbidity and mortality in malaria endemic countries. The mosquito vectors depend on environmental conditions, such as temperature rainfall, for reproduction survival. To investigate the potential weather driven early warning systems to prevent disease occurrence, relationship conditions need be carefully investigated. Where meteorological observations are scarce, satellite derived products provide new opportunities study patterns depending...