Aim: Assessment is a very important component of the medical course curriculum. Item analysis process collecting, summarizing, and using information from student's responses to assess quality multiple-choice questions (MCQs). Difficulty index (P) discrimination (D) are parameters used evaluate standard MCQs. The aim study was Materials Methods: conducted in Department Pathology. One hundred twenty, 2nd year MBBS students took MCQs test comprising 40 questions. There no negative marking...

Context: The data on histological and receptor status in breast cancer an Indian population is limited as not routinely carried out for these patients. In the present study, was analyzed it correlated with morphological prognostic parameters. Objective: To analyze parameters its correlation women. Design: sample consisted of 126 specimens invasive received department pathology our institution teaching hospital attached to it, situated South Canara district of, Karnataka, India between year...

Epidermal growth factor receptor (EGFR) stands out to being a key player in promoting the progression an invasive, metastatic state prostate cancer (PCa). However, precise molecular mechanisms regulating EGFR relation early detection and recurrence advanced stages are still unclear. Thus, current study, we investigated protein expression of PCa patients mouse tissue by immunohistochemistry western blot technique using cell lines. Relative its associated microRNAs (miRNAs) circular RNAs...

Trichoblastic carcinoma is a rare malignancy. Here, we present the case of man in his mid-40s with recurrent ulcer. Histological findings are positive for trichoblastic carcinoma. The patient completed radiotherapy and currently on chemotherapy. carcinomas have no retraction clefts or peripheral palisade. Immunohistochemistry (IHC) was done to narrow diagnosis further, showing CD-10 positivity. Since their management methods vary, emphasise differentiating basal cell from

Abstract Introduction Fixation is the critical step in preservation of tissues diagnostic pathology. The formalin an economical and excellent fixative with inherent property adequate fixation. well-established side effects include mucosal irritation, upper respiratory diseases, corrosive injury to gastrointestinal tract. In addition, substantial evidence exists regarding potential role formaldehyde as a human carcinogen. carcinogenic toxic encourage searching for alternative fixatives tissue...

The incidence of hydatidiform mole is 1 per 1000 pregnancies.The occurrence in ruptured tubal pregnancy very rare.We report an unusual case molar the right fallopian tube which presented as adherent adnexal mass.The present conveys importance histological examination products conception helps pathologist to provide appropriate diagnosis, thereby clinician can offer counseling and follow up patient.[Table /Fig-1]: Cut surface showing dilated lumen containing small tiny glistening cyst (arrow)...

ABSTRACT Epignathus is an extremely rare oropharyngeal teratoma that commonly arises from the palate, leading to a high mortality (80-100%) due airway obstruction in neonatal period. We present case of epignathus immature with fetiform features, originating basisphenoid 28-week preterm male baby, who succumbed death immediately after birth. Since life-threatening condition at time delivery, prenatal diagnosis essential coordinate treatment and appropriate management by securing airway,...

Abstract Background: ABO and Rh blood groups are most important in human beings. The frequency of four main group systems varies population throughout the world even different parts country. Objective if this study was to identify distribution system. Materials methods: conducted rural tertiary care hospital from January 2008 December 2012. Data were collected Blood Bank grouping records. All samples processed during period observation included study. Results: During total 43,103 numbers...

OBJECTIVE: Intraspinal endometriosis is an extremely rare condition with characteristic symptoms, including lower back pain that increases in severity during each menstrual cycle. METHODS: Here, we report a case of involving the conus cauda region. This patient presented acute deterioration secondary to hemorrhage. We also review relevant literature. RESULTS: Magnetic resonance imaging scans dorsolumbar region showed mass lesion within spinal canal at L1–L2 level evidence The underwent...

Background: Glioblastoma (GBM) is the most malignant and accounts for 60% of brain tumors in adults. Current therapy GBM involves surgical removal tumor followed by radiotherapy with concomitant adjuvant temozolomide. Despite improvements therapy, patient survival remains low. The exact etiology a uncertain, numerous unknown genes are involved progression GBM. aim present study was to evaluate various through bioinformatic approach. Methods: In study, gene expression profile GSE68424...

The incidence of renal cell carcinoma has been steadily increasing. There are several morphological types carcinoma. Recognizing histologic patterns is important for correct diagnosis and subsequent medical care the patient. Melanotic tumors in kidney very rare. Here, we present an unusual case with melanin pigment.

Imerslund Grasbeck syndrome (IGS) is a rare autosomal recessive childhood disorder characterized by selective Vitamin (vit) B 12 malabsorption with asymptomatic proteinuria without any structural renal pathology. The patients stay healthy for decades life-long parenteral vit B12. We report case of young female who presented pancytopenia and proteinuria, evaluated in local hospitals as chronic hemolytic anemia (autoimmune cause), finally diagnosed IGS on complete evaluation. She was treated...

ABSTRACT Intracranial xanthogranulomas are rare benign tumors and occur most commonly as choroid plexus xanthogranulomas, which rarely become symptomatic. Exact etiology is still a matter of debate. We present case xanthogranuloma the third ventricle, causing obstructive hydrocephalus lateral ventricles.

BACKGROUNDCancer of the breast is second most common cause cancer in women.Benign or malignant lesions presenting as mass causes anxiety to patients and family members. AIMS AND OBJECTIVES OF THE STUDY1. To classify different types breast, both benign malignant.2. Histomorphological study various lesions.3. spectrum associated with diseases. SETTING DESIGNAll biopsies, lumpectomies, mastectomy specimens Department Pathology our institution between June 2012 2014. MATERIALS METHODSA sample...

Background: The most frequent and aggressive primary brain tumor, glioblastoma (GBM) has an extremely poor prognosis. Several studies have shown the involvement of sex hormonal receptors growth factor in onset GBM. Recent research highlighted importance inflammatory biomarkers as useful prognostic indicators survival outcome predictions several cancer. Based on pretreatment blood tests, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), eosinophil-to-lymphocyte (ELR) been...

Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer and accounts for 90% of head neck malignancies. Intracranial metastases SCC are extremely rare. We reporting a case 55-year-old female with history recurrent swelling over right side forehead which was previously reported as cylindroma. CT scan revealed irregular lytic areas in frontal bone suggestive erosion. There were multiple small, rim enhancing lesions bilateral parietal regions. Clinically it diagnosed...

Co-existence of mucinous cystadenocarcinoma with mature cystic teratoma in the same ovary is very rare. We report a case 48-year-old female who presented left abdominal mass. CT scan revealed heterogeneous enhancing ovarian mass lesion. Clinical diagnosis complex cyst was made, later underwent laparotomy and histologically diagnosed as (grade 2) co-existing benign teratoma, stage Ia (FIGO) ovary. Six months after surgery, patient doing well without any recurrence or metastasis. Hence,...