A5006070384- Sarcoma Diagnosis and Treatment
- Soft tissue tumor case studies
- Tumors and Oncological Cases
- Dermatology and Skin Diseases
- Vascular Malformations and Hemangiomas
- Neonatal skin health care
- Eosinophilic Disorders and Syndromes
- Autoimmune and Inflammatory Disorders
- Autoimmune Bullous Skin Diseases
- melanin and skin pigmentation
- Skin and Cellular Biology Research
- Receptor Mechanisms and Signaling
- Nail Diseases and Treatments
- Genetic and rare skin diseases.
- Nicotinic Acetylcholine Receptors Study
- Immunodeficiency and Autoimmune Disorders
- RNA regulation and disease
- Soft tissue tumors and treatment
- Cancer and Skin Lesions
- Urticaria and Related Conditions
- Oral Health Pathology and Treatment
- Systemic Lupus Erythematosus Research
- Cutaneous lymphoproliferative disorders research
- Allergic Rhinitis and Sensitization
- Dupuytren's Contracture and Treatments
University of Florida
2016-2025
Bundeswehrzentralkrankenhaus Koblenz
2025
Florida College
2016-2024
Jacksonville College
2023
Mayo Clinic in Florida
2022-2023
WinnMed
2022-2023
Florida Atlantic University
2018-2023
Commonwealth Medical College
2022
University of North Carolina at Chapel Hill
2022
Malcom Randall VA Medical Center
2022
Chronic skin disorders in children frequently are visible and can cause stigmatization. However, the extent of stigmatization from chronic disease association with mental health needs further study.
The α3β4 subtype of nicotinic acetylcholine receptors (nAChRs) has been implicated in mediating nicotine reinforcement processes. AT-1001 recently described as a high-affinity and selective nAChR antagonist that blocks self-administration rats. aim this study was to investigate the mechanism action underlying nicotine-suppressive effects AT-1001.Effects were determined using vitro assays rat models addiction, compared with varenicline.AT-1001 its analogue AT-1012 functionally antagonists for...
Alcohol and nicotine are often co-abused. Although the N/OFQ-NOP receptor system is considered a potential target for development of drug abuse pharmacotherapies, especially alcoholism, little known about role this in dependence. Furthermore, effect prior history dependence on subsequent alcohol taking understudied. Using an operant co-administration paradigm, which rats concurrently self-administer alcohol, we found that dependent increased self-administration over time as compared to...
Atopic dermatitis affects 20% to 25% of children and has significant impact on quality life patients families. Recent studies the pathogenesis AD highlight interplay between a defective skin barrier, immune dysfunction, cutaneous microbiome. Standard care for treatment includes topical corticosteroids active disease moisturization repair barrier defect. Emerging treatments include dupilumab Janus kinase (JAK) inhibitors. Reduction triggers proactive with and/or calcineurin inhibitors can...
Abstract Linear morphea of the limb primarily affects children, and extracutaneous manifestations are common. Orthopedic surgeons often essential in care patients with linear morphea, yet there few reports outlining specific orthopedic complications this population. We sought to improve understanding limb. Between 1999 2014, 51 children were evaluated for an extremity. Twenty‐six (51%) had documented manifestations. Outcome measures included length discrepancy, angular malalignment, atrophy,...
Migraine is a disabling disorder characterized by recurrent headaches, accompanied abnormal sensory sensitivity and anxiety. Despite extensive historical use of cannabis in headache disorders, there limited research on the nonpsychoactive cannabidiol (CBD) for migraine no scientific evidence to prove that CBD an effective treatment. The effects are examined here using calcitonin gene-related peptide (CGRP)-induced model provides measures cephalic allodynia, spontaneous pain, altered light...
Abstract Background: Penile and scrotal swelling can occur as an extraintestinal manifestation of Crohn's disease ( CD ) is thought to be uncommon form metastatic MCD ). Because the rarity this manifestation, much unknown concerning presentation, treatment, response therapy in children with genital . Methods: Boys ages 1 17 years presenting edema a confirmed diagnosis or strong suspicion who were evaluated at Mayo Clinic between 1996 2014 included for review. We sought characterize clinical...
The nociceptin/orphanin FQ opioid peptide (NOP) receptor system plays a significant role in the regulation of pain. This functions differently spinal cord and brain. mechanism by which NOP agonists regulate pain transmission these regions is not clearly understood. Here, we investigate peripheral distribution antinociceptive effects intrathecal (N/OFQ) chronic neuropathic
Background The nociceptin/orphanin FQ opioid peptide (NOP) receptor and its endogenous ligand N/OFQ have been implicated in the regulation of drug alcohol use disorders (AUD). In particular, evidence demonstrated that NOP activation blocks reinforcing motivating effects across a range behavioral measures, including intake, conditioned place preference, vulnerability to relapse. Methods Here, we show pharmacological inhibition receptors on binge‐like consumption, as measured by “drinking...
To assess the management and outcomes of afebrile infants who received a pediatric dermatology consultation for pustules and/or vesicles.