A5049102809- Cervical Cancer and HPV Research
- Antibiotic Resistance in Bacteria
- Viral-associated cancers and disorders
- Dermatology and Skin Diseases
- Amoebic Infections and Treatments
- Streptococcal Infections and Treatments
- Virus-based gene therapy research
- Antimicrobial Peptides and Activities
- Lung Cancer Research Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Autophagy in Disease and Therapy
- Bacterial Infections and Vaccines
- Retinoids in leukemia and cellular processes
- Immune Cell Function and Interaction
- vaccines and immunoinformatics approaches
- Antifungal resistance and susceptibility
- Plant Pathogens and Fungal Diseases
- Lung Cancer Diagnosis and Treatment
- Neonatal and Maternal Infections
- Infectious Encephalopathies and Encephalitis
- Fungal Infections and Studies
- Autoimmune Bullous Skin Diseases
- Antibiotic Use and Resistance
- Immune Response and Inflammation
- IL-33, ST2, and ILC Pathways
Southern Medical University
2023-2024
Nanfang Hospital
2023-2024
Chongqing University
2023
Xiamen University
2020
First Affiliated Hospital of Xiamen University
2020
Abstract Human papillomavirus (HPV) infection poses a significant threat to public health worldwide. Targeting the function of HPV E6 and E7 proteins activating host immune response against these represent promising therapeutic strategies for combating HPV-related diseases. Consequently, efficient production soluble, high-purity is crucial studies. In this context, we selected pMCSG19 protein expression vector Escherichia coli produce soluble MBP-His 6 tagged HPV11/16 E6/E7 proteins,...
Acne vulgaris is a complex skin disease involving infection by Cutibacterium acnes, inflammation, and hyperkeratinization. We evaluated the activity of retinoid 6-[3-(adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) 16 other analogs as potential anti-C. acnes compounds found that CD437 displayed highest antimicrobial with an MIC against C. (ATCC 6919 HM-513) 1 μg/mL. demonstrated MBC 2 μg/mL compared to up 64 for adapalene tetracycline, which are commonly used clinically...
Abstract Background: T helper (Th) cells are involved in the pathogenesis of pemphigus vulgaris (PV). However, mechanism still needs more exploration. Aims: This study aimed to evaluate molecular dysregulation Th17 peripheral blood patients with PV. Materials and Methods: Serum levels IL-17 anti-Dsg3 titres PV were analysed using ELISA. The mRNA expression retinoic acid orphan receptor γt (RORγt) CD4 + was detected reverse transcription–quantitative PCR (qPCR). number examined flow...
Abstract Human papillomavirus (HPV) 11/16 E6/E7 proteins have been recognized to be pivotal in viral pathogenesis. This study sought uncover the potential mechanisms of how HPV11/16 E6/E7-transfected keratinocytes inhibit cytokine secretion peripheral blood mononuclear cells (PBMC). Upon co-culturing with PBMC a non-contact manner, we observed marked decrease various cytokines secreted by PBMC. To determine if this suppression was mediated specific common factors, conducted transcriptomic...
Abstract Background Raoultella planticola(R.planticola) is a very rare opportunistic pathogen and sometimes even associated with fatal infection in pediatric cases. Recently,the emergence of carbapenem resistance strains are constantly being reported growing source concern for pediatricians. Case presentation We 4 cases neonatal septicemia caused by planticola. Their gestational age was 211 to 269 days, their birth weight 1490 3000 g.The R. planticola infections were detected on the 9th 27th...