A5010495195- Atherosclerosis and Cardiovascular Diseases
- Immune Response and Inflammation
- Peptidase Inhibition and Analysis
- Carbohydrate Chemistry and Synthesis
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Imaging and Diagnostics
- Protease and Inhibitor Mechanisms
- Bioactive Compounds and Antitumor Agents
- Ferroptosis and cancer prognosis
- Steroid Chemistry and Biochemistry
- Enzyme Catalysis and Immobilization
- Microbial Metabolites in Food Biotechnology
- Pharmacological Effects of Natural Compounds
- Cardiac Fibrosis and Remodeling
- Microbial Natural Products and Biosynthesis
- Glycosylation and Glycoproteins Research
- Cardiovascular Function and Risk Factors
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Ginseng Biological Effects and Applications
- Cardiomyopathy and Myosin Studies
- Endoplasmic Reticulum Stress and Disease
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- MicroRNA in disease regulation
- Plant biochemistry and biosynthesis
Affiliated Hospital of Youjiang Medical University for Nationalities
2011-2024
First Affiliated Hospital of Jinan University
2019-2024
Southwest Hospital
2023-2024
Myocardial ischemia-reperfusion injury (MIRI) is characterized by inflammation and ferroptosis, but the precise mechanisms remain unknown. This study used single-cell transcriptomics technology to investigate changes in various cell subtypes during MIRI regulatory network of ferroptosis-related genes immune infiltration.
Aims The pathogenesis of disease progression targets for patients with heart failure after acute myocardial infarction was investigated by using plasma proteomics. Methods proteomes (MI-HF) and without (MI-WHF) were compared. Each group consisted 10 who matched age sex. peptides analyzed 2-dimensional liquid chromatography coupled to tandem mass spectrometry in a high definition mode. Parallel reaction monitoring (PRM) verified the selected target proteins. Results We identified quantified...
Objective . Multiple genes have been identified to cause dilated cardiomyopathy (DCM). Nevertheless, there is still a lack of comprehensive elucidation the molecular characteristics for DCM. Herein, we aimed uncover putative features DCM by multiomics analysis. Methods Differentially expressed (DEGs) were obtained from different RNA sequencing (RNA‐seq) datasets left ventricle samples healthy donors and patients. Furthermore, protein‐protein interaction (PPI) analysis was then presented....
α1‑antitrypsin (AAT) is a protein released as part of the anti‑inflammatory response. It regulates activity serine proteinases and has crucial role in pathogenesis acute coronary syndrome (ACS). The present study aimed to examine its patients with ACS. plasma samples 117 were collected at Cardiology Department Affiliated Hospital Youjiang Medical University (Baise, China). These included 46 cases ACS (who met diagnostic criteria for had ≥50% luminal stenosis any vessel), 35 stable angina...
Abstract In this study, bufalin was glycosylated by an efficient chemo‐enzymatic strategy. Firstly, 2‐chloro‐4‐nitrophenyl‐1‐ O ‐ β‐ D‐glucoside (sugar donors) obtained chemical synthesis. Then, the glycosylation of achieved with synthesized sugar donor under catalysis two glycosyltransferases (Loki and ASP). Finally, glycosides, i. e., bufalin‐3‐ β ‐D‐glucopyranoside ‐[ ‐D‐glucopyranosyl‐(1→2)‐ ‐D‐glucopyranoside)], were preparative HPLC. Compared to our previously reported sole (total...
The present study attempted to determine the correlation of degree coronary artery stenosis and Tolllike receptor 2/4 (TLR2/4) levels in Chinese Zhuang patients with heart disease (CHD). A total 466 from Ethnic population diagnosed CHD at Department Cardiology Affiliated Hospital Youjiang Medical University between January 2016 August 2017, together 102 control patients, were recruited for study. divided into three groups depending on number diseased arteries. also classified according their...
Resina Draconis (RD), also known as 'dragon's blood', contains a broad range of natural compounds, such flavonoids, stilbenes and dihydrochalcones. It is clinically used to enhance blood circulation. However, the major components RD suffer from relatively poor water solubility. Glycosylation critical determinant for modulating solubility improving bioavailability bioactivity products. Herein, we report novel method efficiently synthesize glycosidic derivatives polyphenols in using microbial...