A5006780095- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Psychiatric care and mental health services
- Adolescent and Pediatric Healthcare
- Health and Medical Studies
- Mental Health and Psychiatry
- Mental Health Treatment and Access
- Diet and metabolism studies
- Psychology, Coaching, and Therapy
- Pharmacology and Obesity Treatment
- Diabetes Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Tryptophan and brain disorders
- Alcoholism and Thiamine Deficiency
- Family Support in Illness
- Sleep and Wakefulness Research
- Genetics and Neurodevelopmental Disorders
- Psychoanalysis and Social Critique
- Ferroelectric and Negative Capacitance Devices
- Posttraumatic Stress Disorder Research
- Electroconvulsive Therapy Studies
- Child and Adolescent Health
- Mindfulness and Compassion Interventions
- Public Administration and Political Analysis
Charité - Universitätsmedizin Berlin
2006-2025
Technische Universität Dresden
2014-2025
University Hospital Carl Gustav Carus
2013-2025
Klinikum im Friedrichshain
2015-2025
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2009-2025
Vivantes Klinikum
2017-2025
University of Economics in Katowice
2024
Klinik und Poliklinik für Psychiatrie und Psychotherapie
2009-2023
University of Tübingen
2022
Justus-Liebig-Universität Gießen
2022
Growing evidence from animal studies indicates brain-damaging properties of nicotine exposure. Investigations in humans found a wide range functional cerebral effects and cigarette smoking, but focusing on brain damage are sparse. In 22 smokers 23 never-smokers possible differences the structures were investigated using magnetic resonance imaging voxel-based morphometry. Significantly smaller grey matter volume lower density (P = 0.05, corrected) observed frontal regions (anterior cingulate,...
Atopic eczema (AE) is a common dermatological condition that causes significant problems in everyday life and high levels of illness-related stress substantial proportions patients. The extent to which adult AE associated with clinically relevant psychiatric morbidity unclear.To investigate the association between major psychiatric/psychosomatic disorders.Case-control study utilizing GKV database Saxony, an interdisciplinary administrative outpatient from Germany. All patients documented as...
Abstract Background Individuals with bipolar disorder are commonly correctly diagnosed a decade after symptom onset. Machine learning techniques may aid in early recognition and reduce the disease burden. As both individuals at risk those manifest display structural brain markers, magnetic resonance imaging provide relevant classification features. Methods Following pre-registered protocol, we trained linear support vector machine (SVM) to classify according their estimated for using...
Bipolar disorders (BD) belong to the most severe mental disorders, characterized by an early onset and recurrent, episodes or a chronic course with poor psychosocial functioning in proportion of patients. Many patients BD experience substantial symptomatology months even years before full manifestation. Adequate diagnosis treatment is often delayed, which associated worse outcome. This study aims prospectively evaluate improve recognition intervention strategies for persons at-risk BD....
Abstract In psychiatry, there has been a growing focus on identifying at-risk populations. For schizophrenia, these efforts have led to the development of early recognition and intervention measures. Despite similar disease burden, populations at risk bipolar disorder not sufficiently characterized. Within BipoLife consortium, we used magnetic resonance imaging (MRI) data from multicenter study assess structural gray matter alterations in N = 263 help-seeking individuals seven sites. We...
The pathophysiology of bipolar disorder (BD) remains mostly unclear. Yet, a valid biomarker is necessary to improve upon the early detection this serious disorder. Patients with manifest BD display reduced volumes hippocampal subfields and amygdala nuclei. In pre-registered analysis, we used structural MRI (n = 271, 7 sites) compare hippocampus, their subfields/nuclei between help-seeking subjects divided into risk groups for as estimated by BPSS-P, BARS EPIbipolar. We performed...
Abstract Aim A substantial gap between young people's need for mental health care services and their actual access to such led worldwide organizations (e.g., the WHO) recommend implementation of early intervention programs youth services. Some countries around world have established structures meet this recommendation. In paper, we describe soulspace as first integrated service people aged 15 35 years in Berlin, Germany. Methods We introduce easily accessible people, characterize along lines...
Persistent poor psychosocial functioning, which is associated with impairments in cognition, one of the main barriers to recovery schizophrenia. Although cognitive remediation therapy (CRT) has shown general efficacy improving cognition and simultaneously focusing on social behavioural processes may increase its efficacy. In a multicenter, rater-blinded, randomized controlled trial, schizophrenia patients (N = 177) were assigned six months either Integrated Social Cognitive Behavioral Skills...
Aripiprazole once-monthly 400 mg (AOM 400) is a long-acting injectable (LAI) for the maintenance treatment of adults with schizophrenia. The AOM two-injection start initiation regimen 400-TIS) an alternative to one injection plus 14 days oral aripiprazole supplementation. This survey investigated real-world experiences European healthcare professionals (HCPs) 400-TIS. Physicians and nurses in Germany, Italy, United Kingdom who had prescribed and/or administered 400-TIS ≥ 3 times patients...
Ratings of treatment goals for patients with schizophrenia have been studied in both and physicians. However, most studies so far, were assessed either by psychiatrists or patients, but not an individual patient case. Therefore, our study from matched physician-patient pairs. First, expert panel created a questionnaire goals, based on systematic literature search. These rated their relevance the 24 independent psychiatrists. In second part study, questionnaires sent to all over Germany....
ABSTRACT Objective To explore the efficiency of IPS on employment, education, and training (EET) outcomes in young adults with early psychosis. Methods Monocenter parallel arm, randomized controlled trial. Intervention Individual placement support (IPS) according to IPS‐Y Fidelity Scale an add‐on up eight sessions adherence therapy. Main outcome measures EET at least 15 h per week for 1 follow‐up. Secondary included rates, duration EET, total wages. Additionally, subsample analyses were...
Das soulspace in Berlin-Kreuzberg ist eine gemeinsame Initiative der lokalen Kontakt- und Beratungsstelle transit Kliniken für Erwachsenenpsychiatrie Kinder- Jugendpsychiatrie Vivantes am Urban im Friedrichshain. Ziel die Schaffung eines niedrigschwelligen sektorübergreifenden Unterstützungsangebotes junge Menschen psychischen Krisen. In Deutschland dieses Angebot bisher einzigartig.
Bipolar disorders (BD) are among the most severe mental with first clinical signs and symptoms frequently appearing in adolescence early adulthood. The long latency diagnosis (and subsequent adequate treatment) adversely affects course of disease, effectiveness interventions health-related quality life, increases economic burden BD. Despite uncertainties about risk constellations symptomatology stages potentially developing BD, many adolescents young adults seek help, them suffer...