A5026249040- Cervical and Thoracic Myelopathy
- Extracellular vesicles in disease
- Bone Tissue Engineering Materials
- MicroRNA in disease regulation
- Heterotopic Ossification and Related Conditions
- Carcinogens and Genotoxicity Assessment
- Hong Kong and Taiwan Politics
- Microbial metabolism and enzyme function
- Climate change impacts on agriculture
- Adenosine and Purinergic Signaling
- Rice Cultivation and Yield Improvement
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Neuroinflammation and Neurodegeneration Mechanisms
- Vitamin C and Antioxidants Research
- Ammonia Synthesis and Nitrogen Reduction
- Agriculture, Soil, Plant Science
- Mesenchymal stem cell research
- Advanced Photonic Communication Systems
- Reproductive System and Pregnancy
- Wound Healing and Treatments
- Orthopaedic implants and arthroplasty
- Pressure Ulcer Prevention and Management
- Catalytic Processes in Materials Science
- Cardiac Arrest and Resuscitation
- Catalysis and Oxidation Reactions
Shanghai Changzheng Hospital
2020-2024
Nanjing Medical University
2024
Kangda College of Nanjing Medical University
2024
Chongqing Three Gorges University
2024
Second Military Medical University
2020-2023
Xuzhou Medical College
2017
Taiyuan University of Technology
2016
Beijing Institute of Optoelectronic Technology
2016
Abstract Background After surgery, wound recovery in diabetic patients may be disrupted due to delayed inflammation, which can lead undesired consequences, and there is currently a lack of effective measures address this issue. Mesenchymal stem cell (MSC)-derived exosomes (Exo) have been proven appropriate candidates for healing through the anti-inflammatory effects. In study, we investigated whether melatonin (MT)-pretreated MSCs-derived (MT-Exo) could exert superior effects on healing,...
Many patients suffer from implant loosening after the implantation of titanium alloy caused by immune response to foreign bodies and this could inhibit following osteogenesis, which possibly give rise aseptic poor osteointegration while there is currently no appropriate solution in clinical practice. Exosome (Exo) carrying miRNA has been proven be a suitable nanocarrier for solving problem. In study, we explored whether exosomes overexpressing miR-181b (Exo-181b) exert beneficial effect on...
Patients with osteoporosis have a high risk of implant loosening due to poor osteointegration, possibly leading failure, revision, and refracture. RNA interference therapy is an emerging epigenetic treatment, we found that miR-20a could enhance osteogenesis. Moreover, small extracellular vesicles (sEVs) derived from bone marrow mesenchymal stem cells (hBM-MSCs) were utilized as nanoscale carriers for the protection transportation (sEV-20a). In this study, intended determine whether sEVs...
Polyetheretherketone (PEEK) exhibits high mechanical strengths and outstanding biocompatibility but biological inertness that does not excite the cell responses stimulate bone formation. The objective of this study was to construct submicro-nano structures on PEEK by femtosecond laser (FSL) for exciting MC3T3-E1 cells gingival epithelial (GE) cells, which induce regeneration bone/gingival tissues long-term stability dental implants.In study, were created surface FSL with power 80 mW (80FPK)...
Ossification of the Posterior Longitudinal Ligament (OPLL) is a degenerative hyperostosis disease characterized by transformation soft and elastic vertebral ligament into bone, resulting in limited spinal mobility nerve compression. Employing both bulk single-cell RNA sequencing, we elucidate molecular characteristics, cellular components, their evolution during OPLL process at resolution, validate these findings clinical samples. This study also uncovers capability stem cells to exhibit...
Pesticides are widely used in agricultural activities. Although pesticide use is known to cause damage the human body, its relationship with thyroid function remains unclear. Therefore, this study aimed investigate association between exposure and function.
Background. Spinal cord injury (SCI) is known to cause a more robust systemic inflammatory response than general trauma without CNS injury, inducing severe secondary organ damage, especially the lung and liver. Related studies are principally focused on mechanisms underlying repair regeneration in injured spinal tissue. However, specific mechanism of after acute SCI widely overlooked, compared with trauma. Methods. Two datasets GSE151371 GSE45376 related blood samples were selected identify...
In this letter, the impact of fiber chromatic dispersion tested on performance chaotic optical time-domain reflectometer (COTDR) is studied. We find that will limit dynamic range COTDR and, hence, deteriorate system considerably. Simple compensation can improve remarkably. Moreover, we show improvement more pronounced for with broader bandwidth. Our experimental results 3.5-GHz bandwidth (3-dB bandwidth), a 1.7-dB be observed when using compensation, whereas 7.6-GHz bandwidth, range, coming...
Abstract Objective To investigate the effects of IL-6, IL-1β, MCP-1, TNF-α, RANTES and IL-10 on osteogenic differentiation Ossification Posterior Longitudinal Ligament (OPLL) cells.Methods: longitudinal ligament was collected during surgical spinal procedures in 5 patients with OPLL. OPLL cells were isolated by enzymatic digestion tissue.The primary cultured passed, post-passage subjected to culture. In process culture, 10-40ng/ml concentrations RANTES, all above factors added...
Abstract Flooding and climate warming lead to the increase of low‐molecular‐weight organic acid (LMWOA) inputs soil. However, it is unclear what effects flooding on soil nitrogen fraction transformation under LMWOA input are. Fluvisol was collected in riparian zone Three Gorges Reservoir conduct an incubation experiment with treatments three LMWOAs at five contents, two hydrological environments temperatures. Compared 0 mg kg −1 , ion exchangeable (IEF‐N), strong oxidant extractable (SOEF‐N)...
We retrospectively investigated the correlation between spinal cord compression angle and increased signal intensity (ISI) in 118 patients with ossification of posterior longitudinal ligament (OPLL). Patients were analyzed based on presence shape ISI magnetic resonance imaging. Various indicators, including angle, measured through imaging examinations. Spearman's logistic regression used for analyses. Significant positive correlations observed grade maximum canal occupying rate, cervical...
Abstract Objective: To investigate the expression of inflammatory cells in patients with Ossification Posterior Longitudinal Ligament Cervical spine (COPLL), and to explore relationship between inflammation COPLL. Methods: The study included 215 OPLL 184 control without For case-control analysis, 147 COPLL demographically matched were through PSM. Leukocyte count, neutrophils, lymphocytes, monocytes, eosinophils, basophils, hs-CRP, EMR, NLR assessed. Furthermore, extent was analyzed.The data...
With advancements in genetics and technology, wheat yields have continuously increased, but grain quality has remained stagnant or even decreased recent decades. The contribution of temperature to the winter future China is not known. This study used improved WheatGrow model, along with two scenarios, quantify regional impacts increases on protein find effective strategies adapt impact quality. results showed that, compared baseline period, average concentration grains main production region...
Abstract Background: Many patients suffer from implant loosening after the implantation of titanium alloy caused by immune response to foreign bodies and this could inhibit osteogenesis, which possibly give rise poor osteointegration there is currently no appropriate solution in clinical practice. Exosomes overexpressing miRNA has been proven be a suitable candidate for solving problem. In study, we explored whether miR-181b exert beneficial effect on promoting M2 macrophage polarization,...