A5060356477- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- Animal Nutrition and Physiology
- Reproductive Physiology in Livestock
- Effects of Environmental Stressors on Livestock
- Genetics and Plant Breeding
- Meat and Animal Product Quality
- Ruminant Nutrition and Digestive Physiology
- Fatty Acid Research and Health
- Animal Behavior and Welfare Studies
- Livestock Management and Performance Improvement
- Livestock and Poultry Management
- Aquaculture Nutrition and Growth
- Animal Genetics and Reproduction
- Rural Development and Agriculture
- Natural Products and Biological Research
- Agriculture Sustainability and Environmental Impact
- Indigenous Studies and Ecology
- Statistical Mechanics and Entropy
- Geography and Environmental Studies
- Regional Economic and Spatial Analysis
- Advanced Statistical Methods and Models
- Milk Quality and Mastitis in Dairy Cows
- Biosensors and Analytical Detection
Universidade de São Paulo
2015-2024
Food & Nutrition
2023
Universidade Federal de Alfenas
2019-2022
Methodist University of Piracicaba
2011-2021
Secretaria de Agricultura e Abastecimento
2014
Universidade Brasil
2013
Instituto de Desenvolvimento Sustentável Mamirauá
2012
Summary Information about genetic parameters is essential for selection decisions and evaluation. These estimates are population specific; however, there few studies with dairy cattle populations reared under tropical sub‐tropical conditions. Thus, the aim was to obtain of heritability correlations milk yield quality traits using pedigree genomic information from a Holstein maintained in environment. Phenotypic records (n = 36 457) 4203 cows as well genotypes 57 368 single nucleotide...
Despite the health concerns and nutritional importance of fatty acids, there is a relative paucity studies in literature that report genetic or genomic parameters, especially case sheep populations. To investigate architecture acid composition sheep, we conducted genome-wide association (GWAS) estimated heritabilities for profile Longissimus dorsi muscle 216 male sheep. Genomic heritability estimates content ranged from 0.25 to 0.46, indicating substantial variation exists evaluated traits....
Feed efficiency helps to reduce environmental impacts from livestock production, improving beef cattle profitability. We identified potential biomarkers (hub genes) for feed efficiency, by applying co-expression analysis in Longissimus thoracis RNA-Seq data 180 Nelore steers. Six modules were associated with six efficiency-related traits (p-value ≤ 0.05). Within these modules, 391 hub genes enriched pathways as protein synthesis, muscle growth, and immune response. Trait-associated...
Background: The impact of extreme changes in weather patterns on the economy and human welfare is one biggest challenges our civilization faces. From anthropogenic contributions to climate change, reducing farming activities a priority since it responsible for up 18% global greenhouse gas emissions. To this end, we tested whether ruminal stool microbiome components could be used as biomarkers methane emission feed efficiency bovine by studying 52 Brazilian Nelore bulls belonging two...
Understanding the architecture of gene expression is fundamental to unravel molecular mechanisms regulating complex traits in bovine, such as intramuscular fat content (IMF) and backfat thickness (BFT). These are economically important for beef industry since they affect carcass meat quality. Our main goal was identify regulatory polymorphisms within genomic regions (QTL) associated with IMF BFT Nellore cattle. For that, we used RNA-Seq data from 193 steers perform SNP calling analysis....
MicroRNAs (miRNAs) are key regulators of gene expression, potentially affecting several biological processes, whose function can be altered by sequence variation. Hence, the integration single nucleotide polymorphisms (SNP) and miRNAs explain individual differences in economic traits. To provide new insights into effects SNPs on their related target genes, we carried out a multi-omic analysis to identify miRNA mature sequences (miR-SNPs) associated with fatty acid (FA) composition Nelore...
The present study aimed to estimate covariance components of milk fatty acids (FA) and compare the genomic estimated breeding values under general heat-stress effects. Data consisted 38,762 test-day records from 6,344 Holstein cows obtained May 2012 through January 2018 on 4 dairy herds Brazil. Single-trait repeatability models with random regressions as a function temperature-humidity index were used for genetic analyses. included contemporary groups, parity order (1-6), days in classes...
For genomic selection to be successful, there must sufficient linkage disequilibrium between the markers and causal mutations. The objectives of this study were evaluate extent LD in ovine using Santa Inês breed infer minimum number required reach reasonable prediction accuracy. In total, 38,168 SNPs 395 samples used. mean adjacent marker pairs measured by r2 |D'| 0.166 0.617, respectively. values ranged from 0.135 0.194 0.568 0.650 for across all chromosomes. average pairwise on each...
In the genetic evaluation of composite cattle or multiracial populations, additive and non-additive effects need to be estimated given their importance in developing strategies for crossing. However, multicollinearity, defined as presence strong linear correlations between explanatory variables, is an obstacle obtaining these estimates, since it produces unstable regression coefficients with large standard errors when least square method used, leading erroneous inferences. Thus, objective...
Abstract Measurements of milk yield (MY), somatic cell score (SCS), percentage fat (FP), protein (PP), lactose (LP), casein (CP) and palmitic (C16:0), stearic (C18:0), oleic (C18:1), total saturated (SFA), unsaturated (UFA), monounsaturated (MUFA) polyunsaturated (PUFA) fatty acids in from 5,224 Holstein cows were evaluated as a function temperature humidity index (THI). Legendre orthogonal polynomials second to seventh order tested. The best fit for MY, PP C18:0 was the third, whereas all...
The objective of this work was to assess the degree multicollinearity and identify variables involved in linear dependence relations additive-dominant models. Data birth weight (n=141,567), yearling (n=58,124), scrotal circumference (n=20,371) Montana Tropical composite cattle were used. Diagnosis based on variance inflation factor (VIF) evaluation condition indexes eigenvalues from correlation matrix among explanatory variables. first model studied (RM) included fixed effect dam age class...
Considering the milk fatty acid influence on human health, aim of this study was to compare gas chromatography (GC) and Fourier transform infrared (FTIR) spectroscopy for determination these compounds. Fatty content (g/100 g fat) were obtained by both methods compared through Pearson's correlation, linear Bayesian regression, Bland–Altman method. Despite high correlations between measurements (r = 0.60–0.92), regression coefficient values indicated higher measures palmitic acid, oleic...
Abstract Mineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype Nelore ( Bos indicus) cattle, we analysed genome-wide mRNA miRNA expression data from 114 samples. The analysis implemented a new application for two complementary algorithms: partial correlation information theory (PCIT) regulatory impact factor (RIF), which included estimated genomic breeding values (GEBVs) phenotypes...
Repeated measures from the same individual have been analyzed by using repeatability and finite dimension models under univariate or multivariate analyses. However, in last decade, use of random regression for genetic studies with longitudinal data become more common. Thus, aim this research was to estimate parameters body weight four experimental chicken lines models. Body hatching 84 days age (n = 34,730) free-range (7P, Caipirão da ESALQ, Caipirinha ESALQ Carijó Barbado) were used. The...
Intramuscular fat (IMF) and backfat thickness (BFT) are critical economic traits impacting meat quality. However, the genetic variants controlling these need to be better understood. To advance knowledge in this area, we integrated RNA-seq single nucleotide polymorphisms (SNPs) identified genomic transcriptomic data generate a linkage disequilibrium filtered panel of 553,581 variants. Expression quantitative trait loci (eQTL) analysis revealed 36,916 cis-eQTLs 14,408 trans-eQTLs. Association...
Chicken is an important source of protein for human nutrition and a model system growth developmental biology. Although the genetic architecture quantitative traits in meat-type chickens has been subject ongoing investigation, identification mutations associated with carcass economic interest remains challenging. Therefore, our aim was to identify predicted deleterious mutation, which potentially affects function, test if they were chickens. For that, we performed genome-wide association...
The inclusion of genetic groups in sire evaluation has been widely used to represent differences among animals not accounted for by the absence parentage data. However, definition these is still arbitrary, and studies assessing effects grouping strategies on selection efficiency are rare. Therefore, aim this study was compare with unknown prediction breeding values (EBV). total 179,302 records weaning weight (WW), 29,825 scrotal circumference (SC), 70,302 muscling score (MUSC) from Montana...
Abstract The objectives of this study were twofold: (1) to identify potential differences in the ruminal and fecal metabolite profiles Nelore bulls under different nutritional interventions; (2) metabolites associated with cattle sustainability related-traits. We used interventions feedlot: conventional (Conv; n = 26), by-product (ByPr, 26). Thirty-eight fluid 27 significantly ( P < 0.05) between ByPr Conv groups. Individual dry matter intake (DMI), residual feed (RFI), observed water...
The growth rate of broilers has triplicated in the last decades. body weight is used as one selection criteria whereas carcass traits are valuable market requirements. Thus, meat industry like animals with high weights at slaughter and better traits. However, genetic relation several unknown. Therefore, we established associations among performance a broiler chicken line estimated gain trends. We also evaluated what age would lead to more efficient indirect data set information different...
Variance components and genetic parameters of economically relevant traits in livestock, whether continuous or categorical, can be estimated by methods computationally available providing support for the selection mating animals breeding programs. The objectives this paper were to obtain compare variance estimates visual under categorical distribution single-trait analysis their correlations with productive two-trait analysis. Data conformation (CONF), precocity fat deposition (PREC)...
Context The economic efficiency of a dairy system is associated with the animal’s productive and reproductive abilities. Therefore, selection criteria should include milk production quality traits as well related to health fertility. Since such phenotypes can present non-normal distributions, use threshold models appropriate study genetic variation traits. Aim To estimate variance components for functional in Brazilian Holstein cattle population using linear under Bayesian approach. Methods...