A5004184562- Cytomegalovirus and herpesvirus research
- Oral microbiology and periodontitis research
- Mindfulness and Compassion Interventions
- Immune Response and Inflammation
- RNA modifications and cancer
- Metabolism and Genetic Disorders
- Phytochemistry and Biological Activities
- Herpesvirus Infections and Treatments
- Hepatitis C virus research
- Ocular Diseases and Behçet’s Syndrome
- Systemic Lupus Erythematosus Research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Cytokine Signaling Pathways and Interactions
- Advanced Manufacturing and Logistics Optimization
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Peroxisome Proliferator-Activated Receptors
- Plant and Fungal Interactions Research
- Bayesian Methods and Mixture Models
- Yersinia bacterium, plague, ectoparasites research
- Ziziphus Jujuba Studies and Applications
- Cancer survivorship and care
- NF-κB Signaling Pathways
- Chromatography in Natural Products
- Food Supply Chain Traceability
- Child Therapy and Development
Chi Mei Medical Center
2025
Academy of Military Medical Sciences
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Sichuan University
2020-2024
Chinese People's Liberation Army
2024
Shandong University
2023-2024
Chinese PLA General Hospital
2024
Institute of Microbiology
2023
The Fourth People's Hospital of Zibo City
2022-2023
Institute of Grassland Research
2023
In this study, the ultrasound-assisted extraction (UAE) conditions of flavonoids from Lactuca indica L.cv. Mengzao (LIM) leaves was optimized, and content their antioxidant potential in different parts were analyzed. The optimal parameters to obtain highest total (TFC) a ratio liquid solid 24.76 mL/g, ultrasonic power 411.43 W, ethanol concentration 58.86% an time 30 min, average TFC LIM could reach 48.01 mg/g. For yield flavonoids, UAE method had best capacity compared with solvent...
Infection with influenza A virus (IAV) can trigger pulmonary inflammation and lung damage. Osteopontin (OPN) is an essential regulator of cell death immunity. However, the role underlying mechanism OPN in IAV-induced injury remain poorly understood. Here, we demonstrated that OPN-deficient (OPN-/-) mice were insensitive to IAV, exhibiting decreased viral loads attenuated after IAV infection compared those wild-type (WT) mice. Moreover, macrophage necroptosis was significantly reduced OPN-/-...
Abstract The seasonal human coronaviruses (HCoVs) have zoonotic origins, repeated infections, and global transmission. objectives of this study are to elaborate the epidemiological evolutionary characteristics HCoVs from patients with acute respiratory illness. We conducted a multicenter surveillance at 36 sentinel hospitals Beijing Metropolis, China, during 2016–2019. Patients influenza‐like illness (ILI) severe infection (SARI) were included, submitted samples for screening by multiplex...
L. cv. Mengzao, a medicinal plant of the Ixeris genus, is rich in flavonoids. In order to thoroughly analyze distribution and dynamic change major flavonoids its various parts from different growth periods, extracted
This study aims to clarify the effects of diabetes mellitus (DM) on inflammatory profile during orthodontic tooth movement (OTM) and explore potential mechanisms.
Demoralization syndrome is prevalence among cancer patients in China. However, little research has examined how demoralization associated with quality of life (QOL). The aims this study were to investigate the relationship between mindfulness state, and QOL thyroid patients, explore mediating effect on QOL. A correlational cross-sectional was performed using an online questionnaire. conducted from July October 2022 310 patients. General information questionnaire, Scale, Five Facet...
Consider the nonparametric regression model <TEX>$Y_{ni}\;=\;g(x_{ni})+{\epsilon}_{ni}$</TEX> (<TEX>$1\;{\leq}\;i\;{\leq}\;n$</TEX>), where g(<TEX>$\cdot$</TEX>) is an unknown function, <TEX>$x_{ni}$</TEX> are known fixed design points, and correlated errors {<TEX>${\epsilon}_{ni}$</TEX>, <TEX>$1\;{\leq}\;i\;{\leq}\;n$</TEX>} have same distribution as {<TEX>$V_i$</TEX>, <TEX>$1\;{\leq}\;i\;{\leq}\;n$</TEX>}, here <TEX>$V_t\;=\;{\sum}^{\infty}_{j=-{\infty}}\;{\psi}_je_{t-j}$</TEX> with...
Abstract Type 2 diabetes (T2D) is a risk factor for mucosal homeostasis and enhances the susceptibility to inflammation, in which neutrophils have been increasingly appreciated their role. Here, barrier disruption inflammation are observed at oral mucosa (gingiva) of T2D patients mice. It demonstrated that infiltrate gingival mice expel obvious neutrophil extracellular traps (NETs), while removal NETs alleviates barrier. Mechanistically, released dependent metabolic reprogramming. Under...
Acute anterior uveitis (AAU) is an ordinary type of uveitis, which autoimmune disease produced by T cells. Programmed apoptosis protein 1 (PD-1) a vital negative regulatory immune tolerance. We detect the single nucleotide polymorphisms (SNPs) rs41386349, rs10204525, and rs2227982 PD-1 to investigate correlation between AAU. A total 166 AAU patients 263 controls were recruited in this case-control study. Compared with controls, frequencies GG genotypes higher rs10204525 (p = 0.012). There...
Abstract Adenosine monophosphate‐activated protein kinase (AMPK) plays pivotal roles in metabolic diseases including type 2 diabetes. However, the specific role of AMPK for orthodontic tooth movement diabetes is unclear. In this study, a diabetic rat model was established through dietary manipulation and streptozocin injection. Examinations were conducted to select qualified rats. Then, an device applied these rats 0, 3, 7, or 14 days. The distance parameters alveolar bone analyzed by...
Sera from 158 individuals in Yanji, Jilin, China, were tested for antibodies to herpes simplex virus type 1 (HSV-1) by the passive hemagglutination method. Age-specific incidence rates HSV-1 calculated. For sera persons age group 10 years or less, positive rate was 54% but higher than years, it more 91% (P less 0.01). In part of China surveyed, primary infection occurred early generation before about 10. children, Han race significantly that Korean 0.05).
Abstract The emerging evidence of human infections with viruses suggests their potential public health importance. A novel taxon named Statoviruses (for st ool‐ a ssociated To mbus‐like viruses) was recently identified in the gastrointestinal tracts multiple mammals. Here we report discovery re spiratory St atovirus‐like (provisionally Restviruses) from respiratory five patients experiencing acute disease Human coronavirus OC43 infection through retrospective analysis meta‐transcriptomic...
Background Bilateral optic neuritis associated with disc swelling is a common feature of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). However, extensive deep retinal haemorrhages have not been described in the context MOG-associated neuritis. Here, we report case infectious mononucleosis marked binocular peripapillary and perivascular as well presence MOGAD. Case A 39-year-old Chinese woman presenting subacute vision reduction no light perception was diagnosed...
Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is an autosomal recessive disorder of the fatty acid oxidative metabolism. This study aimed to investigate epidemiological characteristics, spectrum variation, clinical phenotype, and prognosis MCADD in Chinese newborns.We retrospectively analysed newborn screening (NBS) data Zibo area from January 2016 March 2022 summarized 42 cases recently reported neonates. High-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)...
Objective: To study the effects of Fe3+ and hemoglobin (Hb) iron on ability Bacillus cereus to grow when isolated from eye. Methods: In this experimental study, 26 patients with post-traumatic endophthalmitis were recruited Eye Hospital, Wenzhou Medical University strains eyes obtained. The divided into a light-perception (LP) group no-light-perception (NLP) group, based whether patient's light perception was preserved after treatment, strain ATCC14579 used as control group. Optical...