A5002218759- Liver Disease Diagnosis and Treatment
- Cholesterol and Lipid Metabolism
- Adipose Tissue and Metabolism
- Antioxidant Activity and Oxidative Stress
- Liver physiology and pathology
- Peroxisome Proliferator-Activated Receptors
- Adipokines, Inflammation, and Metabolic Diseases
- Fungal Biology and Applications
- Cancer, Lipids, and Metabolism
- Liver Disease and Transplantation
- Phytochemicals and Antioxidant Activities
- Seaweed-derived Bioactive Compounds
- Sirtuins and Resveratrol in Medicine
- Tea Polyphenols and Effects
- Diet, Metabolism, and Disease
- Algal biology and biofuel production
- Fatty Acid Research and Health
- Alcohol Consumption and Health Effects
- Histone Deacetylase Inhibitors Research
- Food Quality and Safety Studies
- Paraoxonase enzyme and polymorphisms
- Hormonal Regulation and Hypertension
- Drug Transport and Resistance Mechanisms
- Lipoproteins and Cardiovascular Health
- Endoplasmic Reticulum Stress and Disease
University of Connecticut
2014-2024
Institute of Forest Science
2024
Korea Forest Service
2023
New York University Press
2021
Cambridge University Press
2021
Yonsei Proteome Research Center
2019
Yonsei University
2019
George Washington University
2017
657 Oslo
2016
University of Nebraska–Lincoln
2007-2012
With no approved pharmacological treatment, nonalcoholic fatty liver disease (NAFLD) is now the most common cause of chronic in Western countries and its worldwide prevalence continues to increase along with growing obesity epidemic. Here, we show that a high‐fat high‐sucrose (HFHS) diet, eliciting hepatosteatosis resembling human liver, lowers hepatic nicotinamide adenine dinucleotide (NAD + ) levels driving reductions mitochondrial content, function, adenosine triphosphate (ATP) levels,...
This study examines the role that business intelligence (BI) and communication technologies play in how firms may achieve organizational sensing agility, decision making acting agility different environmental contexts. Based on information-processing view of organizations dynamic capability theory, we suggest a configurational analytic framework departs from standard linear paradigm to examine IT’s effect is embedded configuration elements. In line with this approach, use fuzzy-set...
Faced with the challenge of multifaceted digital phenomena, researchers in IS and related fields have increasingly adopted qualitative comparative analysis (QCA). However, absence explicit guidelines for how to use QCA theory development, t
Guinea pigs were fed a hypercholesterolemic diet (0.25 g/100 g cholesterol) and randomly allocated either to Control group (n = 9) or Lutein (0.1 g) 10) for 12 weeks evaluate oxidative stress inflammation in both liver eyes.Malondialdehyde (MDA) concentrations inflammatory cytokines measured as well hepatic nuclear factor-kappaB (NF-κB) binding.Lutein greater eyes (P < 0.01) 0.001) the group.All guinea had high of cholesterol plasma ALT AST levels indicative injury.However, 43% lower free...
Non-alcoholic fatty liver disease (NAFLD) is significantly associated with hyperlipidaemia and oxidative stress. We have previously reported that astaxanthin (ASTX), a xanthophyll carotenoid, lowers plasma total cholesterol TAG concentrations in apoE knockout mice. To investigate whether ASTX supplementation can prevent the development of NAFLD obesity, male C57BL/6J mice ( n 8 per group) were fed high-fat diet (35 %, w/w) supplemented 0, 0·003, 0·01 or 0·03 % (w/w) for 12 weeks. The...
It has been established that nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB) members promote survival by upregulating antiapoptotic genes and genetic pharmacological inhibition NF‐κB is required for tumor necrosis (TNF)‐induced hepatocyte apoptosis. In this study, we demonstrate pro‐survival pathway switched to pro‐apoptosis under pyruvate dehydrogenase kinase 4 (PDK4)‐deficient conditions. PDK4‐deficiency triggered hepatic apoptosis concomitantly with increased...