A5039662116- Chromosomal and Genetic Variations
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Genomics and Phylogenetic Studies
- Insect Resistance and Genetics
- Genetic Mapping and Diversity in Plants and Animals
- Research in Cotton Cultivation
- Plant tissue culture and regeneration
- Plant Disease Resistance and Genetics
- Plant Genetic and Mutation Studies
- Glaucoma and retinal disorders
- Tissue Engineering and Regenerative Medicine
- Plant Reproductive Biology
- Osteoarthritis Treatment and Mechanisms
- Retinal Diseases and Treatments
- Molecular Biology Techniques and Applications
- Nerve injury and regeneration
- Plant Virus Research Studies
- Mitochondrial Function and Pathology
- Medical Research and Treatments
- Spine and Intervertebral Disc Pathology
- Cardiomyopathy and Myosin Studies
- Mosquito-borne diseases and control
- RNA modifications and cancer
- Reproductive System and Pregnancy
Chinese Academy of Agricultural Sciences
2021-2025
Beijing YouAn Hospital
2018-2025
Capital Medical University
2013-2025
Nankai University
1994-2025
Biotechnology Research Institute
2021-2024
Qufu Normal University
2009-2024
South China Agricultural University
2024
Sichuan University of Science and Engineering
2021-2023
Sichuan Research Center of New Materials
2022-2023
University of Electronic Science and Technology of China
2014-2023
Tissue-specific extracellular matrix plays an important role in promoting tissue regeneration and repair. We hypothesized that decellularized annular fibrosus may be appropriate scaffold for engineering. aimed to determine the optimal decellularization method suitable fibrosus. Annular was treated with 3 different protocols Triton X-100, sodium dodecyl sulfate (SDS) trypsin. After process, we examined cell removal preservation of components, microstructure mechanical function treatments...
A method to functionalize single-walled carbon nanotubes (SWNTs) in a field-effect transistor (FET) device for the selective detection of heavy-metal ions is presented. In this method, peptide-modified polymers were electrochemically deposited onto SWNTs and metal was demonstrated by choosing appropriate peptide sequences. The signal transduction mechanism SWNT-FETs has also been studied.
Ochratoxins were important secondary metabolites secreted by fungi, and OTA OTB are mainly significant mycotoxin, having toxic effects on humans animals. Therefore, it is to establish a rapid, sensitive precise method for ochratoxins detection quantification in real samples. In this study, stable monoclonal antibody (mAb) that recognizing both toxins was employed the establishment of indirect competitive ELISA (ic-ELISA), colloidal gold nanoparticles (CGNs) nanoflowers strips (AuNFs) A 6E5...
Epigenetic modifications function in gene transcription, RNA metabolism, and other biological processes. However, multiple factors currently limit the scientific utility of epigenomic datasets generated for plants. Here, using deep-learning approaches, we developed a Smart Model Epigenetics Plants (SMEP) to predict six types modifications: DNA 5-methylcytosine (5mC) N6-methyladenosine (6mA) methylation, (m6 A) three histone modification. Using from japonica rice Nipponbare, SMEP achieved 95%...
An aligned and well-distributed carbon nanotubes array was produced by pyrolysis of hydrocarbons catalyzed nickel nanoparticles embedded in porous silicon (PS) substrates. Scanning electron microscope images show that the form an approximately perpendicular to surface PS substrate diameters most tubes within are 10–30 nm. High-magnification transmission microscopy confirmed well graphitized typically consist about 15 concentric shells sheets. Furthermore, strong field emission from emitter observed.
ABSTRACT Bifidobacterium longum DJO10A was previously demonstrated to produce a lantibiotic, but only during growth on agar media. To evaluate the feasibility of production this lantibiotic in broth media, transcription analysis lanA gene undertaken. Comparative microarray and cultures B. revealed that production, modification, transport/peptidase, immunity genes were significantly upregulated cultures, while two-component regulatory expressed equally under both conditions. This suggested...
Summary RNA editing plays an important role in organellar gene expression plants, and pentatricopeptide repeat ( PPR ) proteins are involved this function. Because of its large family size, many not known for their function roles plant growth development. Through genetic molecular analyses the empty pericarp18 emp18 mutant maize Zea mays ), we cloned Emp18 gene, revealed function, defined mitochondrial complex assembly seed encodes a mitochondrial‐localized DYW ‐ protein. Null mutation...
Tissue engineering has provided an alternative therapeutic possibility for degenerative disc diseases. However, we lack ideal scaffold IVD tissue engineering. The goal of this study is to fabricate a novel biomimetic biphasic and evaluate the feasibility developing tissue-engineered in vitro vivo. In present developed integrated using simple freeze-drying cross-linking technique pig bone matrix gelatin (BMG) outer annulus fibrosus (AF) phase acellular cartilage ECM (ACECM) inner nucleus...
CYP6F1 (GenBank/EMBL accession No. AY662654), a novel gene with complete encoding sequence in the cytochrome P450 family 6, was cloned and sequenced from deltamethrin-resistant 4th instar larvae of Culex pipiens pallens. The cDNA has an open reading frame 1527 bp, which encodes putative protein 508 amino acid residues. deduced indicated that encoded conserved domains membrane-anchoring signal, reductase-binding sites, typical heme-binding site, ETLR motif substrate recognition sites....
Diammonium glycyrrhizinate (DG) is a replacement for glycyrrhizic acid, which used as hepatic protector in clinical practice most liver diseases. The potential role of immune response during autoimmune hepatitis-induced by concanavalin A (Con A)-remains to be elucidated.C57BL/6J mice were treated with two different doses DG (75 and 200 mg/kg) 2 hrs before administering Con A. sacrificed after 0, 6, 24 hrs. Liver damage grade serum alanine aminotransferase (ALT), aspartate (AST) total...
<title>Abstract</title> RNA 5-methylcytidine (m5C) has been identified as a key epi-transcriptomic modification of mRNAs involved in regulating multiple post-transcriptional processes. Here, we found that knockout the m5C demethylase, OsNOP2, results elevated levels and positively influences numerous agronomic traits rice. After verifying OsNOP2 demethylase function vitro planta, enhanced arising from increased translation, particularly for transcripts carbon assimilation nitrogen...
HPV infection and DNA integration can lead to cervical cancer, but the relationship with lesion severity is unclear. This study aimed investigate correlation between profile extent. Twenty patients representing cervicitis, CIN I, II, III underwent nanopore sequencing for genotype site analysis. profiles were correlated severity. Gene Ontology (GO) KEGG analysis used identify stage-specific genes pathways. rates 60, 100, 100% III, respectively, varying numbers of integrated genes. Each group...
Four similar dinuclear lanthanide complexes have been synthesized by linking two [Ln(hfac)2–3] units (hfac stands for hexafluoroacetylacetone) with different μ-O bridging ligands. The 2,2′-bipyridine-N-oxide ligand (bmpo) constructed centrosymmetric [Ln2(hfac)6(bmpo)2] (Ln = Dy(1), Tb(2)), nine-coordinated LnIII ions showing Cs low symmetry, while the di(2-pyridyl)methanediol (py2C(OH)2) formed another compounds [Ln2(hfac)4(py2C(OH)O)2] Dy(3), Tb(4)), kinds of eight-coordinated exhibiting...