A5083484947- Pleural and Pulmonary Diseases
- Tracheal and airway disorders
- Lung Cancer Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Airway Management and Intubation Techniques
- Medical Imaging and Pathology Studies
- Autoimmune and Inflammatory Disorders
- Pneumonia and Respiratory Infections
- Nosocomial Infections in ICU
- Respiratory viral infections research
- Esophageal and GI Pathology
- Pneumocystis jirovecii pneumonia detection and treatment
- Tuberculosis Research and Epidemiology
- Foreign Body Medical Cases
- Vascular Anomalies and Treatments
- Fungal Infections and Studies
- Trauma Management and Diagnosis
- Inflammatory mediators and NSAID effects
- Metastasis and carcinoma case studies
- Pneumothorax, Barotrauma, Emphysema
- Diverticular Disease and Complications
- Cystic Fibrosis Research Advances
- Cardiac tumors and thrombi
Mayo Clinic in Arizona
2015-2025
Mayo Clinic Hospital
2016-2023
Pulmonary Associates
2016-2022
Mayo Clinic
2014-2019
Mayo Clinic in Florida
2014-2019
WinnMed
2014-2018
Griffin Hospital
1970
Memorial Hospital
1970
University of Oklahoma Medical Center
1970
ABSTRACT The health care-associated pneumonia (HCAP) criteria have a limited ability to predict caused by drug-resistant bacteria and favor the overutilization of broad-spectrum antibiotics. We aimed derive validate clinical prediction score with an improved risk due pathogens compared that HCAP criteria. A derivation cohort 200 microbiologically confirmed cases in 2011 2012 was identified retrospectively. Risk factors for were evaluated logistic regression, novel (the drug resistance [DRIP]...
ABSTRACT The FilmArray respiratory panel (FARP) reliably and rapidly identifies 17 viruses 3 bacterial pathogens. A nasopharyngeal swab FARP (NP FARP) is performed for many patients with symptoms. For who are acutely ill or immunocompromised fail to improve, a bronchoalveolar lavage sample (BAL in addition the NP FARP. To date, no studies have compared yield of BAL that an We retrospectively studied all had within 7 days after between June 2013 May 2014. Demographic information,...
Molindone, a new indole derivative, was evaluated as an antipsychotic agent with the use of double‐blind placebo‐controlled technique. Antipsychotic activity relative to placebo apparent, although it did not appear impressive that standard drug, chlorpromazine. A possible alerting effect associated molindone apparent Side effects were no more frequent than those seen usual psychotropic drugs.
Transbronchial cryobiopsies (CB) are increasingly replacing surgical biopsies (video-assisted thoracoscopic/VATS biopsies) for diagnosing diffuse parenchymal lung disease (interstitial disease, ILD), but there is very little guidance pathologists on CB interpretation. Here we propose a fairly simple approach. First, if the diagnosis can be made traditional forceps biopsy, it cryobiopsy. Many diseases with specific features will fall into this category (eg, sarcoidosis or Langerhans cell...
Background . The FilmArray Respiratory Panel (FARP) (BioFire Diagnostics, Inc.) is a multiplex, polymerase chain reaction (PCR) technique that can detect 17 respiratory viruses and 3 bacterial targets in single reaction. Immunocompromised hosts (ICH) with illnesses often undergo bronchoscopy bronchoalveolar lavage (BAL). This prospective study aimed to evaluate the yield concordance of NP BAL FARP testing when performed on same patient concurrently. Methods From February December 2016, 125...
To assess the contribution and safety of bronchoscopic cryobiopsy vs traditional forceps biopsy used in clinical practice for diagnosing diffuse parenchymal lung disease (DPLD).We identified 271 patients who underwent DPLD at Mayo Clinic, MN (June 1, 2013, through September 30, 2017). Medical records were reviewed including prebiopsy radiographic impressions. Diagnostic yield was assessed terms a specific histologic pattern resulting diagnosis when combined with clinical-radiologic context....
The modifying effects of a cyclooxygenase (cox)-2 selective inhibitor nimesulide on tongue carcinogenesis were investigated in male F344 rats initiated with 4-nitroquinoline-1-oxide (4-NQO). cell proliferation activity measured by proliferating nuclear antigen (PCNA)-positive index and apoptotic index, the immunohistochemical expression COX-2, inducible nitric oxide synthase (iNOS) mucosa or neoplasms also examined for mechanistic analysis carcinogenesis. All animals except those treated...
Background: Patients with advanced emphysema experience breathlessness due to impaired respiratory mechanics and diaphragm dysfunction. Bronchoscopic lung volume reduction (BLVR) is a minimally invasive bronchoscopic procedure done reduce hyperinflation air trapping, promoting atelectasis in the targeted lobe allowing improved mechanics. Real-world data on safety complications outside of clinical trials BLVR are limited. Methods: We queried US Food Drug Administrations (FDA) Manufacturers...
Objective . To determine whether results of the nasopharyngeal FilmArray respiratory panel (NP-FARP) influenced antibiotic decisions. Methods We reviewed medical records nonintensive care unit (ICU) inpatients that had an NP-FARP performed at our institution between June 2013 and 2014. The inpatient were 48 hours after for following data: demographic information; NP-FARP, serum procalcitonin, methicillin-resistant Staphylococcus aureus nasal swab (MRSA NS) results; antibiotics prior post-48...
Nitrofurantoin-induced lung toxicity is relatively common, but rare histologic patterns sometimes occur that may make diagnosis difficult. We present the case of a 69-year-old woman taking prophylactic nitrofurantoin for urinary tract infections, who developed granulomatous interstitial pneumonia. She improved with cessation nitrofurantoin, without other therapy. To our knowledge, this fourth reported pneumonia associated and first to show complete resolution drug alone, steroids. It...
Abstract Purpose Stem cell transplant ( SCT ) recipients commonly undergo bronchoalveolar lavage BAL collection as an infectious pulmonary work‐up. Previous studies report the utility and overall diagnostic yield of fiberoptic bronchoscopy with in this vulnerable population, though none focused purely on microbiologic or made comparisons less invasive means pathogen detection. We sought to determine elaborate recipients, assess a correlation between detection, repeating within 30 days....
The serum procalcitonin assay has emerged as a promising biomarker to distinguish between bacterial and viral respiratory tract infections but not been used differentiate coccidioidomycosis from infection. A correlation levels never reported.To determine any association primary pulmonary coccidioidomycosis.We identified enrolled 20 immunocompetent patients with symptomatic of < 8 weeks' duration performed one-time assay, cutoff 0.25 μg/L indicating nonbacterial infection.Nineteen (95%) had...
Pyoderma gangrenosum is a chronic sterile skin disorder that frequently seen in association with systemic disorders such as inflammatory bowel disease. Extracutaneous pyoderma rare and most commonly occurs the lungs. It particularly unusual for extracutaneous to manifest prior findings without an associated disorder. A 19-year-old white man presented shortness of breath productive cough. His exam was normal. Unenhanced chest computed tomography showed peripheral consolidations, areas...
A bronchopleural fistula (BPF) is a communication between the pleural space and bronchial tree. BPFs are challenging to diagnose associated with high morbidity mortality. Sequential balloon occlusion commonly used for localization of BPF. We describe our experience 4 cases successful BPF by instillation methylene blue into through pigtail catheter, simultaneous bronchoscopic visualization dye in tracheobronchial Two patients were treated endobronchial valves 3 had surgical thoracic muscle...
Bronchopleural fistula (BPF) is a feared complication of pulmonary resection. Fistula plugs (FP) have been described as an adequate treatment in anorectal disease. We describe our early experience placing FP the BPF. retrospectively reviewed 5 patients for whom was placed BPF at institution. Demographic data, initial perioperative information, method and technique placement, success reported. Five (4 male, 1 female) with median age 63 years (range, 57–76 years) underwent 6 placements Two...
Central airway obstruction (CAO) often requires repeated interventional procedures which offer variable efficacy, a time-limited effect, and have inherent limitations. Paclitaxel has been used to prevent restenosis in blood vessels. The literature describing the use of paclitaxel recurrent stenosis is limited. We sought describe our experience using paclitaxel-coated balloon (PCB) for CAO. performed retrospective review all patients who underwent PCB dilation. collected: basic demographics,...