A5101891828- Migraine and Headache Studies
- Psychosomatic Disorders and Their Treatments
- Angiogenesis and VEGF in Cancer
- SARS-CoV-2 and COVID-19 Research
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- 3D Printing in Biomedical Research
- Atherosclerosis and Cardiovascular Diseases
- Gene Regulatory Network Analysis
- Protease and Inhibitor Mechanisms
- Posttraumatic Stress Disorder Research
- Cardiac Imaging and Diagnostics
- Abdominal Surgery and Complications
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cerebral Venous Sinus Thrombosis
- Maternal Mental Health During Pregnancy and Postpartum
- Case Reports on Hematomas
- Pneumothorax, Barotrauma, Emphysema
- Cardiovascular Disease and Adiposity
- COVID-19 and healthcare impacts
- Cancer Cells and Metastasis
- Tissue Engineering and Regenerative Medicine
- Mathematical Biology Tumor Growth
University of Virginia
2021-2024
The University of Texas at Austin
2022-2024
Christiana Care Health System
2013-2021
Drexel University
2008-2009
University of Toledo
2008-2009
NorthShore University HealthSystem
2009
Maimonides Medical Center
2009
Stratford University
2009
Nashville Oncology Associates
2009
University of California, Berkeley
2009
To assess and contrast the relative frequency of self-reported post-traumatic stress disorder (PTSD) in patients with episodic migraine chronic/ transformed migraine.Several risk factors have been identified as for chronification headache disorders. Childhood abuse has suggested a factor chronic pain adulthood. In addition depression, well several other psychiatric disorders, are co-morbid migraine. Recent data suggest that PTSD may be more common sufferers than general population.This was...
Objective.— To evaluate the relative frequency of posttraumatic stress disorder (PTSD) in episodic migraine (EM) and chronic daily headache (CDH) sufferers impact on headache‐related disability. Background.— Approximately 8% population is estimated to have PTSD. Recent studies suggest a higher PTSD disorders. The association disability has not been examined. Methods.— A prospective study was conducted at 6 centers. assessed using life events checklist checklist, civilian version (PCL‐C). We...
Significance We report a vaccine platform to express antigens on the surface of genome-reduced bacteria enhance immunogenicity. demonstrate utility this by expressing highly conserved fusion peptide (FP) SARS-CoV-2 and porcine epidemic diarrhea virus Escherichia coli produce killed whole-cell bacterial vaccines. The primes potent anamnestic response, potentiates interferon-γ responses, provides significant protection in pigs against disease following challenge. FP could be target for broadly...
Abstract Human induced pluripotent stem cell differentiated cardiomyocytes (hiPSC-CMs) hold great potential to resolve cardiovascular disease but are stymied by their functional immaturity. The complex electric potentials measured during cardiogenesis point the of exogenous electrical stimulation in improving cardiac differentiation and functionality. Herein, we create, validate, implement a low-cost device stimulate hiPSCs differentiation. Notably, our open-source enables generation regimes...
Background: Coronary artery disease (CAD) is one of the leading causes death worldwide. The buildup atherosclerotic plaque, including lipids and cellular waste, characterizes this disease. Smooth muscle cells (SMCs) can migrate proliferate to form a fibrous cap that stabilizes plaque in response buildup. However, some severe cases, unable prevent rupture, which lead thrombotic event causing stroke or myocardial infarction. Studies have been conducted identify genes associated with influence...
Purpose: With multiple groups generating methods for differentiating induced pluripotent stem cells (hiPSCs) into endothelial cells/endothelial progenitors (ECs/EPs), there is a need to better understand the specific subtypes that different differentiation protocols produce. This especially important accurate tissue modeling as researchers continue incorporate endothelium engineered tissues. Methods: We illustrated heterogeneity of produced from by focusing on two selected protocols, one...
Abstract As the coronavirus disease 2019 (COVID-19) pandemic rages on, it is important to explore new evolution-resistant vaccine antigens and platforms that can produce readily scalable, inexpensive vaccines with easier storage transport. We report here a synthetic biology-based platform employs an expression vector inducible Gram-negative autotransporter express on surface of genome-reduced bacteria enhance interaction antigen immune system. proof principle, we utilized E. coli SARS-CoV-2...
Purpose: In a previous study, we found higher detection rate of 2nd and 3rd order vascular thrombosis when CT Perfusion (CTP) was performed as compared to non-contrast (NCCT) angiography (CTA) alone. Additionally, significant number patients with acute infarct were reported negative without CTP. this sought determine whether missed imaging diagnosis CTP might affect clinical decision making. Methods: A total 758 cases included in our deficits all 71 final volume 2.8 ml or above. Conversely,...
Purpose: The role of CT Perfusion (CTP) in evaluation acute stroke remains controversial, especially determining ischemic penumbra and core infarct. Thus, our institution suspended CTP as part the imaging protocol, now includes a non-contrast head (NCCT) angiography (CTA) neck. We performed retrospective review cases using NCCT, CTA (CT-CTP) NCCT (CT-CTA protocol) at from 2009 to 2011, assess what, if any, substantial benefit provides management stroke. Methods: A total 758 were reviewed,...
Image A: Axial contrast enhanced abdominal CT of a 64 year old man demonstrated wedge shaped region hypoenhancement at the medial midpole left kidney, compatible with segmental renal infarction (arrow).Image B: noncontrast head multiple areas acute to subacute in superior parietal lobe (arrows).