A5036828977- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Tissue Engineering and Regenerative Medicine
- Orthopaedic implants and arthroplasty
- Titanium Alloys Microstructure and Properties
- Parkinson's Disease Mechanisms and Treatments
- biodegradable polymer synthesis and properties
- Cardiac Valve Diseases and Treatments
- Biosensors and Analytical Detection
- Advanced Sensor and Energy Harvesting Materials
- Diet and metabolism studies
- Silk-based biomaterials and applications
- Polymer Surface Interaction Studies
- Advanced Polymer Synthesis and Characterization
- Conducting polymers and applications
- Tuberculosis Research and Epidemiology
- Nanoparticle-Based Drug Delivery
- Dental Implant Techniques and Outcomes
- Infective Endocarditis Diagnosis and Management
- Advanced materials and composites
- Graphene and Nanomaterials Applications
- Mycobacterium research and diagnosis
- Hemoglobinopathies and Related Disorders
Science Oxford
2023-2024
Seattle University
2023-2024
Iowa Policy Project
2023-2024
Queensland University of Technology
2019-2022
St Vincent's Hospital
2021-2022
Deakin University
2012-2021
Rice University
2016-2019
St Joseph's Hospital Health Center
2019
Geelong Hospital
2016
National University of Singapore
2011
It is commonly accepted that titanium and the alloying elements of tantalum, niobium, zirconium, molybdenum, tin, silicon are biocompatible. However, our research in development new alloys for biomedical applications indicated some containing produced by powder metallurgy show a certain degree cytotoxicity. We hypothesized cytotoxicity linked to ion release from metals. To prove this hypothesis, we assessed both forms bulk, using osteoblast-like SaOS 2 cells. Results metal powders titanium,...
Abstract Elemental metals have been widely used to alloy metallic orthopedic implants. However, there is still insufficient research data elucidating the cell responses of osteoblastic cells alloying elemental metals, which impedes development new implant materials. In this study, cellular osteoblast‐like (SaOS2) 17 pure that is, titanium (Ti), zirconium (Zr), hafnium (Hf), vanadium (V), niobium (Nb), tantalum (Ta), chromium (Cr), molybdenum (Mo), manganese (Mn), iron (Fe), ruthenium (Ru),...
ABSTRACT Pathogenic bacteria often need to survive in the host and environment, it is not well understood how cells transition between these equally challenging situations. For human animal pathogen Salmonella enterica serovar Typhimurium, biofilm formation correlated with persistence outside a host, but connection virulence unknown. In this study, we analyzed multicellular-aggregate planktonic-cell subpopulations that coexist when S . Typhimurium grown under biofilm-inducing conditions....
Porous titanium (Ti) and alloys are promising scaffold biomaterials for bone tissue engineering, because they have the potential to provide new ingrowth abilities low elastic modulus match that of natural bone. In present study, a highly porous Ti6Ta4Sn alloy with addition biocompatible alloying elements (tantalum (Ta) tin (Sn)) was prepared using space-holder sintering method. The strength porosity 75% found be significantly higher than pure Ti same porosity. can customized human by...
To address the increasing demand for safe and effective treatment options pelvic organ prolapse (POP) due to worldwide ban of traditional polypropylene meshes, this study introduced degradable polycaprolactone (PCL)/polyethylene glycol (PEG) composite meshes fabricated with melt-electrowriting (MEW). Two PCL/PEG mesh groups: 90:10 75:25 (PCL:PEG, wt%) were characterized their degradation rate mechanical properties, PCL used as a control. The composites showed controllable rates by adjusting...
The fabrication of patient-specific scaffolds for bone substitutes is possible through extrusion-based 3D printing calcium phosphate cements (CPC) which allows the generation structures with a high degree customization and interconnected porosity. Given brittleness this clinically approved material, stability open-porous cannot always be secured. Herein, multi-technological approach allowed simultaneous combination CPC melt electrowriting (MEW) polycaprolactone (PCL) microfibers in an...
Electrically conductive scaffolds are of significant interest in tissue regeneration. However, the chemistry existing usually lacks bioactive features for effective interaction with cells. In this study, poly(ε-caprolactone) was electrospun into aligned nanofibers 0.58 µm average diameter. Electrospinning followed by polypyrrole coating on surface fibers, which resulted 48 kΩ/sq resistivity. An oxygen plasma treatment conducted to change hydrophobic fiber mats a hydrophilic substrate. The...
The in-vitro susceptibility of Mycobacterium tuberculosis, M. bovis, and kansasii to amoxycillin alone in combination with 2 mg/l clavulanic acid was evaluated by broth dilution. MIC90 plus 4 compared > 32 for when tested against tuberculosis (n = 27). bovis 8) the most susceptible species an 8 mg/l, 0.5 combination. 6), 16 more resistant than either or bovis. Ticarcillin less active 28) acid. addition greatly improves its activity
In this study a largely available lignocellulose feedstock hemp (Cannabis sativa), obtained as an industrial waste, was used for cellulose extraction. The extraction of microfibres from biomass conducted by alkaline treatment and acidification process. extracted were characterised using Fourier-transformed infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), thermogravimetric analysis (TGA) X-ray diffraction (XRD). viability the determined growing human fibroblasts on...
Although luminal delivery of butyrate is one putative mechanism by which biology the colonic epithelium might be influenced changes in contents, there a paucity supportive cause-effect evidence. This study aimed to directly establish whether distal able alter response carcinogen.Groups male Sprague-Dawley rats with chronically intubated colons received infusions 80 mM or 0.9 percent saline into colon two five times daily. Three weeks after exposure azoxymethane (15 mg/kg subcutaneously),...
Native heart valve leaflets are subjected to continuous pulsatile and homodynamic forces can be as thin 300 μm. For a proper function of the materials selected for need biocompatible, robust, flexible, have comparable mechanical properties natural ones. In this paper, biocompatibility cell retention ability gelatin–chitosan polyurethane (PU), polyglycolide (PGA)/PLA collagen-coated bovine pericardium were examined their tested. Endothelial cells, isolated from ovine carotid arteries seeded...