A5058485690- Vector-borne infectious diseases
- Viral Infections and Vectors
- Insect and Pesticide Research
- Virology and Viral Diseases
- Research on Leishmaniasis Studies
- Pneumonia and Respiratory Infections
- Herpesvirus Infections and Treatments
- Mosquito-borne diseases and control
- Dermatological diseases and infestations
- Parasites and Host Interactions
- Vector-Borne Animal Diseases
- Cytomegalovirus and herpesvirus research
- Bacterial Infections and Vaccines
- COVID-19 epidemiological studies
- Tuberculosis Research and Epidemiology
- Rabies epidemiology and control
- SARS-CoV-2 and COVID-19 Research
- Mycobacterium research and diagnosis
- Peripheral Neuropathies and Disorders
- SARS-CoV-2 detection and testing
- Infectious Diseases and Tuberculosis
- Vaccine Coverage and Hesitancy
- Zoonotic diseases and public health
- Otolaryngology and Infectious Diseases
- Venomous Animal Envenomation and Studies
Region Västra Götaland
2008-2025
Sahlgrenska University Hospital
1989-2018
University of Gothenburg
1989-2014
To provide evidence-based recommendations on the treatment of nervous system Lyme disease and post-Lyme syndrome. Three questions were addressed: 1) Which antimicrobial agents are effective? 2) Are different regimens preferred for manifestations disease? 3) What duration therapy is needed?The authors analyzed published studies (1983-2003) using a structured review process to classify evidence related posed.The panel reviewed 353 abstracts which yielded 112 potentially relevant articles that...
SARS-CoV-2 was discovered among humans in Wuhan, China late 2019, and then spread rapidly, causing a global pandemic. The virus found to be transmitted mainly by respiratory droplets from infected persons or direct contact. It also shown excreted feces, why we investigated whether the could detected wastewater if so, which extent its levels reflects society. Samples of city Gothenburg, surrounding municipalities Sweden were collected daily mid-February until June 2020 at Rya treatment plant....
Twenty-nine patients, aged 11–79 years (mean, 50 years), with Lyme neuroborreliosis, facial nerve palsy, and meningitis were treated oral doxycycline (daily dose, 200–400 mg) for 9–17 days in a prospective, nonrandomized study. Facial paresis was bilateral eight (28%) of the 29 patients. Twenty-six patients (90%) recovered without sequelae within 6 months, while three palsy at admission had remaining follow-up. In five contralateral developed 1–12 after initiation therapy, two retreated...
This prospective, open-label, non-randomized trial at the University Departments of Infectious Diseases in Ljubljana, Slovenia, and Göteborg, Sweden, was conducted to compare kinetics cerebrospinal fluid (CSF) mononuclear cell count after 10–14 d ceftriaxone or doxycycline for treatment Lyme neuroborreliosis. 29 patients were treated with intravenous 2 g daily Ljubljana 36 oral 400 mg Göteborg. The study protocol included lumbar puncture before 6–8 weeks initiation. There a marked decrease...
Twelve patients were treated orally with 100 mg of doxycycline twice a day (b.i.d.) and 10 200 b.i.d. for suspected tick-borne neuroborreliosis (Lyme borreliosis). At 5 to 8 days after the start therapy, mean concentrations in serum 4.7 micrograms/ml dose 7.5 b.i.d., 2 3 h last drug administration. The corresponding levels cerebrospinal fluid 0.6 1.1 micrograms/ml. Since concentration above estimated MIC Borrelia burgdorferi (0.6 0.7 microgram/ml) is wanted severe neuroborreliosis, higher preferable.
Background and purpose The treatment recommendation for L yme neuroborreliosis with central nervous system ( CNS ) symptoms is intravenous ceftriaxone, according to current A merican E uropean guidelines. For peripheral PNS symptoms, ceftriaxone oral doxycycline considered equally effective. of this study was evaluate the efficacy in symptoms. Methods Patients who had undergone cerebrospinal fluid CSF sampling before after at D epartment I nfectious iseases, S ahlgrenska U niversity H...
Ehrlichioses are emerging infections in the United States. Human granulocytic ehrlichiosis (HGE) and Lyme borreliosis (LB) acquired after Ixodes ricinus-complex tick bites. An ongoing seroepidemiologic study of 185 356 permanent residents Koster Islands Sweden was expanded to include ehrlichioses. Ehrlichial antibodies were measured by IFA using Ehrlichia equi chaffeensis. Borrelia burgdorferi IgG ELISA-seropositive subjects confirmed Western blot. E. chaffeensis (titer ⩾80) found 21 (11.4%)...
Cerebrospinal fluid (CSF) neopterin levelswere determined by RIA in individuals with central nervous system (CNS) or human immunodeficiency virus (HIV) infections and healthy controls. The mean CSF concentrations were 63.0 nmoljL 15 patients acute bacterial meningitis, 54.9 nmol/L Lyme neuroborreliosis, 32.5 10 viral 130.9 8 encephalitis, 13.9 asymptomatic HIV infection, 26.0 11 AIDS without dementia, 65.4 4 4.2 24 Although encephalitis had higher levels than any other patient category...
In the tsunami catastrophe in Thailand 2004, several thousand Swedish tourists were injured, with contaminated crush trauma of legs being main cause injury among survivors.Patient and laboratory data for those who received hospital care Stockholm Gothenburg contracted late-onset infections due to rapid-growing mycobacteria reviewed retrospectively. Also, concomitant recorded.Fifteen patients skin soft-tissue are described here. Mycobacterium abscessus was isolated 7 cases, fortuitum 6...
In an outbreak of measles in Gothenburg, Sweden, breakthrough infections (i.e. individuals with a history vaccination) were common. The objective this study was to compare RNA levels between naïve primary) and infections. We also propose fast provisional classification Medical records reviewed real-time PCR-positive samples genotyped. Cases classified as naïve, or vaccine compared clinical symptoms cycle threshold (Ct) values Sixteen 28 confirmed cases A classification, based on previous...
Abstract A nested polymerase chain reaction was used for the detection of Epstein‐Barr virus DNA in 1 patient with encephalitis, and myelitis. detected cerebrospinal fluid samples obtained at onset neurological symptoms both patients, serological findings indicated ongoing infection. In herpes simplex type transiently fluid, while still present on day 44 after admittance. Single‐photon emission computed tomography this a frontal bilateral hypoperfusion. The diagnostic value serum infections...
For public health purposes, it is essential to understand which population groups and their areas of residence are affected by a disease as COVID-19 what extent these reached preventive measures. We investigated how individual-level area-level characteristics associated with morbidity vaccine uptake. A population-based observational study including the total adult age 18 older in Sweden from 1 January 2020 April 2022, except individuals living nursing homes. Associations between both...
We describe an imported case of Lassa fever with both encephalopathy and bilateral sensorineural hearing deficit. Absence during hospitalization, initially nonspecific symptoms, onset deficit in a late stage disease probably contributed to delayed diagnosis (14 days after admittance hospital). The pathogenesis neurological manifestations is poorly understood no specific treatment was given. A total 118 personnel had close contact the patient, but secondary cases occurred. This highlights...
Study Type – Therapy (case series) Level of Evidence 4 What's known on the subject? and What does study add? Intravesical BCG treatment has been used worldwide for many decades but there are only a few published reports persisting infection urinary bladder. This is first report large tuberculosis‐like ulcers bladder after intravesical treatment. The finding results in recommendation to take urine cultures mycobacteriae patients with unclear inflammatory lesions instillation BCG. OBJECTIVE To...
Leishmaniasis is a neglected and poorly reported parasitic infection transmitted by sand flies in tropical subtropical regions. Knowledge about leishmaniasis has become important non-endemic countries due to increased migration travel. Few studies of the clinical management cutaneous, mucocutaneous visceral regions have been published date. In this study, we aimed evaluate patient characteristics, manifestations treatments Sweden, over 20-year period. A retrospective observational nationwide...
Is Lyme neuroborreliosis, even in its early phase, a parenchymatous disorder the central nervous system (CNS), and not merely meningitic process? We quantified cerebrospinal fluid (CSF) levels of four nerve glial cell marker proteins neuroborreliosis patients with pretreatment durations 7–240 days. AH 23 had meningo‐radiculitis, six objective signs encephalopathy. Glial fibrillary acidic protein (GFAp) CSF, light subunit neurofilament (NFL) were related to clinical outcome declined...
Sweden is investigating an outbreak of monophasic Salmonella Typhimurium. Eighty-two nationally-distributed cases have been confirmed, with date symptom onset between 28 August and 29 October. Cases were 51 years age on average (range: 0-89) the majority female (62%). A case-control study was conducted suggested small tomatoes as source (adjusted odds ratio (OR): 10.8, 95% confidence interval (CI): 4.15-112.68, p value < 0.001), a trace-back investigation led to single, non-Swedish producer...
In January-February 2008, one imported case of measles initiated a series exposures with around 380 nosocomial secondary contacts. Susceptible individuals were traced early and control measures that managed to limit the consequences considerably. Only four cases identified by end March. This minor outbreak illustrates importance efficiency as well fact risk outbreaks still exists in country has high measles, mumps, rubella vaccination coverage among children.
Binary file ES_Abstracts_Final_ECDC.txt matches