- Renal Diseases and Glomerulopathies
- Liquid Crystal Research Advancements
- Pediatric Urology and Nephrology Studies
- Molecular spectroscopy and chirality
- Surfactants and Colloidal Systems
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Genetic and Kidney Cyst Diseases
- Urinary Tract Infections Management
- Biofuel production and bioconversion
- Spectroscopy Techniques in Biomedical and Chemical Research
- Poisoning and overdose treatments
- Biomedical Research and Pathophysiology
- Vasculitis and related conditions
- Genetic Syndromes and Imprinting
- Urinary Bladder and Prostate Research
- Spectroscopy and Chemometric Analyses
- Cardiovascular Health and Disease Prevention
- Photochemistry and Electron Transfer Studies
- Hormonal Regulation and Hypertension
- Ion Transport and Channel Regulation
- Enzyme Production and Characterization
- Electrolyte and hormonal disorders
- Potassium and Related Disorders
- Vaccine Coverage and Hesitancy
Chang Gung Memorial Hospital
2011-2025
Chang Gung University
2013-2025
Ming Chi University of Technology
2025
First Affiliated Hospital of Henan University
2023
Zhengzhou People's Hospital
2023
Memorial
2022
Memorial Hospital of South Bend
2022
Linkou Chang Gung Memorial Hospital
2016-2022
Imperial College London
2018
Tunghai University
2017
Abstract More reliable biomarkers using near-patient technologies are needed to improve early diagnosis and intervention for patients with renal disease. Infrared (IR) vibrational spectroscopy/microspectroscopy is an established analytical method that was first used in biomedical research over 20 years ago. With the advances instrumentation, computational mathematical techniques, this technology has now been applied a variety of diseases; however, applications nephrology just beginning...
Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine and counterregulator of glucocorticoids, is potential therapeutic target. MIF markedly different from other cytokines because it constitutively expressed, stored in the cytoplasm, present circulation healthy subjects. Thus, concept targeting for intervention challenging need to neutralize ubiquitous protein. In this article, we report that occurs two redox-dependent conformational isoforms. We show one isoforms MIF, is,...
Patterns of disease and therapeutic responses vary widely among patients with autoimmune glomerulonephritis. This study introduces groundbreaking personalized infrared (IR)-based diagnostics for real-time monitoring status treatment in lupus nephritis (LN). We have established a relative absorption difference (RAD) equation to assess characteristic spectral indices based on the temporal peak heights (PHs) two serum bands: ν1 as target signal ν2 PH reference band, measured at each dehydration...
The purpose of this study was to investigate influenza vaccination coverage and the factors influencing acceptance among patients with diabetes in Taiwan using Health Belief Model (HBM). From January 1 February 28, 2012, 700 who visited National Cheng Kung University Hospital were invited participate study. A total 691 (99%) enrolled mean age subjects 64.7 years (SD = 10.7). percentages received seasonal 31%, 33%, 35% 2009-2010, 2010-2011, 2011-2012, respectively. Multiple regression...
Systemic lupus erythematosus (SLE) is associated with atherosclerosis, but the relationship between SLE and peripheral arterial occlusive disease (PAOD) remains unclear. We sought to investigate this by comparing cardiovascular complications in patients without SLE. Data on from 2000 2011 were collected National Health Insurance Research Database of Taiwan. The cohort was frequency-matched according age, sex, history diabetes mellitus (DM) (control cohort). evaluated risk complications,...
Rheumatoid arthritis (RA) is associated with atherosclerosis. However, the relationship between RA and peripheral arterial occlusive disease (PAOD) remains unclear. We used a national health insurance database to identify cohort of 30,812 patients diagnosed 2000 2011. Each patient was frequency-matched according age sex without from control cohort. A multivariate Cox proportional hazards model analyse adjusted risk PAOD. The incidence PAOD 1.73-fold higher (95% confidence interval [CI] =...
Aim: This was a nationwide study by National Health Insurance Research Database to investigate the risk of urinary tract cancers (UTCs) for renin–angiotensin–aldosterone system inhibitors including spironolactone. Methods: A total 32 167 UTC patients with hypertension were enrolled in program between 2005 and 2011. Results: Among different subclasses inhibitors, adjusted odds ratio (OR) 1.00 [95% confidence interval (CI) = 0.96–1.04] angiotensin-converting enzyme 1.22 (95% CI 1.18–1.26) who...
Percutaneous renal biopsy (PRB) is essential for the diagnosis, prognosis, and management of children with unknown kidney disease. In this study, safety efficacy PRB investigated, also common etiologies childhood disease, based on histological findings. addition, we explored role PRBs in diagnosis who presented persistent asymptomatic hematuria.By chart review, from July 2005 to 2009, a total 99 were performed 91 (43 girls 48 boys; mean age, 10.9 ± 4.4 years) under ultrasound (US) guidance,...
Abstract Purpose Acute kidney injury (AKI) is commonly seen in neonatal intensive care units (NICUs) and potentially associated with adverse prognoses later stages of life. Our study evaluated the impact sustained AKI (SAKI) on both neurodevelopmental impairment (NDI) early growth restriction (EGR) neonates. Methods This case-control retrospectively analyzed medical records neonates diagnosed SAKI NICU a tertiary center during period from January 2007 to December 2020. Cases without...
Cardiovascular complications remain the major problems contributing to morbidity and mortality in patients with polycystic kidney disease (PKD). Therefore, authors hypothesized that atrial fibrillation (AF) is closely associated PKD. The conducted a nationwide population-based cohort study investigate risk of AF Using data from inpatient claims, enrolled 7203 aged over 20 years who were diagnosed PKD 1998 2010 no history as cohort. They randomly selected 28,739 people without controls...
Four simple rodlike Schiff base mesogens with tolane moiety were synthesized and applied to stabilize cubic blue phases (BPs) in binary mixture systems for the first time. When chiral additive or was added into a salicylaldimine-based compound, temperature range of BP could be extended by more than 20 °C. However, when mesogen blended dopant possessing opposite handedness, , BPs not observed. Interestingly, widest (∼35 °C) induced adding racemic hydroxyl group. On basis our experimental...
Data on the risk of neurodegenerative diseases, including Alzheimer disease (AD) and Parkinson (PD), in patients with polycystic kidney (PKD) are lacking.A total 4,229 who were aged ≥20 years had received a diagnosis PKD included cohort. For each case identified, 1 participant without history PKD, dementia, or PD was selected from comparison patient corresponding controls 1:1 basis nearest propensity score calculated using logistic regression.The incidence density rates dementia 4.31 2.50...
BackgroundThis study evaluated the prevalence and frequency of serum electrolyte abnormalities (SEAs) in children presenting to a pediatric emergency department (PED) with various diseases.MethodsPediatric patients (≤18 years) blood panels obtained PED Lin-Kou Chang Gung Memorial Hospital, Taiwan, 5 years from January 1, 2016, August 31, 2021, were enrolled this retrospective observational study. Patients divided into three age groups: Group A, < 4 years; B, 4–11 C, 12–18 years. The...