- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Nutritional Studies and Diet
- Adipokines, Inflammation, and Metabolic Diseases
- Eating Disorders and Behaviors
- Consumer Attitudes and Food Labeling
- Mitochondrial Function and Pathology
- Diet, Metabolism, and Disease
- Nutrition and Health in Aging
- Obesity and Health Practices
- Body Contouring and Surgery
- Health and Lifestyle Studies
- Regulation of Appetite and Obesity
- Vascular Procedures and Complications
- Biochemical effects in animals
- Pregnancy and preeclampsia studies
- Liver Disease Diagnosis and Treatment
- Genetics, Aging, and Longevity in Model Organisms
- Appendicitis Diagnosis and Management
- COVID-19 and Mental Health
- Sirtuins and Resveratrol in Medicine
- Cerebrovascular and Carotid Artery Diseases
- Educational and Social Studies
- Obesity, Physical Activity, Diet
- Human Health and Disease
University of Molise
2014-2024
Ceinge Biotecnologie Avanzate (Italy)
2009
University of Naples Federico II
2008
University of Milan
2003-2006
IRCCS Eugenio Medea
2005
University of Urbino
2005
IRCCS Ospedale San Raffaele
2005
Luigi Sacco Hospital
2003-2005
IRCCS Istituto Auxologico Italiano
2005
Federico II University Hospital
2000
Nitric oxide was found to trigger mitochondrial biogenesis in cells as diverse brown adipocytes and 3T3-L1, U937, HeLa cells. This effect of nitric dependent on guanosine 3′,5′-monophosphate (cGMP) mediated by the induction peroxisome proliferator–activated receptor γ coactivator 1α, a master regulator biogenesis. Moreover, induced exposure cold markedly reduced adipose tissue endothelial synthase null-mutant (eNOS –/– ) mice, which had metabolic rate accelerated weight gain compared...
Calorie restriction extends life span in organisms ranging from yeast to mammals. Here, we report that calorie for either 3 or 12 months induced endothelial nitric oxide synthase (eNOS) expression and 3′,5′-cyclic guanosine monophosphate formation various tissues of male mice. This was accompanied by mitochondrial biogenesis, with increased oxygen consumption adenosine triphosphate production, an enhanced sirtuin 1. These effects were strongly attenuated eNOS null-mutant Thus, plays a...
Background and aimsFollowing the Covid-19 proliferation beyond borders of China at beginning 2020, containment measures have been taken by different countries around globe. Citizens were forced to stay home. The aim this study is twofold. First, we will provide an analysis food consumption in Italy during emergency from a social stance. Secondly, consider risks relation health these product choices.Methods resultThis based on IRi's data trends (percentage increase sales value) first period...
There have been only a few reports illustrating the moderate effectiveness of suicide-preventive interventions in reducing suicidal behavior, and, most those studies, target populations were primarily adults, whereas focused on adolescents. Essentially, there no randomized controlled studies comparing efficacy, cost-effectiveness and cultural adaptability suicide-prevention strategies schools. is also lack information whether can, addition to preventing suicide, reduce risk behaviors promote...
To evaluate the accuracy of ultrasonography in diagnosis acute calculous cholecystitis comparison with other imaging modalities. The authors performed a search Medline/ PubMed (National Library Medicine, Bethesda, Maryland) for original research and review publications examining cholecystitis. design utilized single or combination following terms : (1) cholecystitis, (2) ultrasonography, (3) computed tomography, (4) magnetic resonance cholangiopancreatography (5) cholescintigraphy. This was...
Ultrasound is a widely used technique in the diagnosis of acute appendicitis; nevertheless, its utilization still remains controversial.The accuracy appendicitis adult patient, as shown literature, was searched for.The gold standard for pathologic confirmation after appendectomy. In published graded-compression has an extremely variable diagnostic (sensitivity range from 44% to 100%; specificity 47% 99% ). This due many reasons, including lack operator skill, increased bowel gas content,...
The benefits of multi-target action are well established in a variety pathological models. Many dietary supplements and nutraceuticals may be useful to slow age-related cognitive declines the risk developing neurodegenerative disease. L-Carnosine EGCG natural compounds that have received particular attention because their potential role modulating oxidative stress associated with aging chronic conditions. biological activities these naturally occurring substances frequently been used prevent...
The study aims to assess the prevalence of obesity, overweight and underweight in children enrolled government primary schools (6–11 years age) city Milan, Italy. One hundred nine were randomly selected for study. A cross-sectional was conducted between March June 2008. survey using 16,588 questionnaires completed by parents. Anthropometric data (reported) both parents information on levels physical activity time spent watching television (TV) obtained. In total sample, are predominantly...
Abstract Purpose Adopting a Mediterranean-like dietary pattern may help in preventing several chronic diseases. We assessed the eating behaviour and compliance with Mediterranean diet pyramid recommendations Italy. Methods This is cross-sectional study conducted subjects aged ≥ 20 years. A 14-question survey based on updated was launched online from April 2015 to November 2016. At test completion, personalized displaying possible deficiencies and/or excesses generated, that could be basis...
Non-alcoholic fatty liver disease (NAFLD) is a health emergency worldwide due to its high prevalence and the lack of specific therapies. Noninvasive biomarkers supporting NAFLD diagnosis are urgently needed. Liver mitochondrial dysfunction central pathomechanism that changes throughout progression. Blood-cell bioenergetics reflecting organ emerging for potential applications in diagnostics. We measured real-time respirometry peripheral blood mononuclear cells (PBMCs), anthropometric...
Isolated abdominal aortic dissection is a rare clinical disease representing only 1.3% of all dissections. There are few case series reported in the literature. The causes this pathology can be spontaneous, iatrogenic, or traumatic. Most patients asymptomatic and symptoms usually back pain, while claudication lower limb ischemia rare. Surgical endovascular treatment two valid options with acceptable results. We herein describe nine cases symptomatic spontaneous isolated dissection, out which...
Severe obesity is a major worldwide public health concern affecting 0.5-5% of the adult population. Adiponectin (Acpr30), an adipokine secreted from adipocytes, shows pleiotropic beneficial effects on and related disorders. In this study, sequence analysis Acpr30 gene (ACDC) was performed in highly selected population severely obese young patients Southern Italy to investigate associations between polymorphisms ACDC development severe concomitantly with other features metabolic syndrome.The...
Ephedrine/caffeine combination (EC) has been shown to induce a small-to-moderate weight loss in obese patients. Several mechanisms have proposed, among which an increased thermogenic capacity of skeletal muscle consequent the EC-induced up-regulation uncoupling protein 3 (UCP3) gene expression. We did parallel group double-blind, placebo-controlled, 4-week trial investigate this hypothesis. Thirteen morbidly women (25-52 years age, body-mass index 48.0±4.0 kg/m2, range 41.1-57.6) were...
Abstract Objective The purpose of this study is to assess the increase both in use Internet and social media Google searches regarding eating disorders (ED) Italy during Covid-19 pandemic. Our aim also verify possible impact such an on ED, since patients treated for ED by National Health Service (NHS) have increased first 6 months 2020 as well. Method We used data from Wearesocial surveys users related query “food disorders” “body shaming.” results a project Italian Ministry been considered...
Abstract Purpose The growing importance placed on health and physical well-being by consumers continues to influence food industry choices. market therefore, pandering the desires for a lean athletic body, offers new products deemed more healthy able impact body image. It is evidenced, thus, change in choices habits, with attention quality nutrient content of consumed, which protein assuming increasing importance. purpose study highlight important changes eating habits particular increase...
Vascular occlusion of hemodialysis arteriovenous access (AVA) using an Amplatzer vascular plug (AVP; St. Jude Medical, Paul, MN, USA) is arising and alternative practice in selected patients; however, few reported cases can be found the literature. Herein, we report on our experience with endovascular treatment complicated AVA.From September 2015 to December 2016, 3 patients at clinic underwent AVA 2 different plugs: type II 1 patient IV. Of these, was treated for autologous radiocephalic...
Abstract The growing importance placed on health and physical well-being by consumers continues to drive the choices of food industry in favor offering new products that pander proclivities toward foods deemed more healthy able impact most coveted body image, lean athletic body. It is evidenced, thus, a change habits, with attention quality nutrient content consumed, which protein assuming increasing importance. Purpose: purpose study highlight important changes eating habits particular...