A5071762492- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Lipoproteins and Cardiovascular Health
- Cardiovascular and exercise physiology
- Infective Endocarditis Diagnosis and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Effects of Exercise
- Blood Pressure and Hypertension Studies
- ECG Monitoring and Analysis
- Heart Rate Variability and Autonomic Control
- X-ray Diffraction in Crystallography
- Cardiac Fibrosis and Remodeling
- Health disparities and outcomes
- Air Quality and Health Impacts
- Liver Disease Diagnosis and Treatment
- Healthcare Systems and Reforms
- Crystallization and Solubility Studies
- Health Systems, Economic Evaluations, Quality of Life
- Acute Myocardial Infarction Research
- Heart rate and cardiovascular health
- Coronary Interventions and Diagnostics
Nanjing Drum Tower Hospital
2016-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
National Clinical Research
2021-2025
Shandong Provincial Hospital
2024
Shandong First Medical University
2024
Shandong University
2024
Peking Union Medical College Hospital
2016-2023
Fujian University of Traditional Chinese Medicine
2022
The First People's Hospital of Changzhou
2021
Soochow University
2021
Importance Limited evidence supports the association between low-density lipoprotein cholesterol (LDL-C) and mortality across different atherosclerotic cardiovascular disease (ASCVD) risk stratifications. Objective To explore associations LDL-C levels to identify optimal ranges of with lowest in populations diverse ASCVD profiles. Design, Setting, Participants The ChinaHEART project is a prospective cohort study that recruited residents aged 35 75 years from 31 provinces mainland China...
<h3>Importance</h3> Body mass index (BMI) is positively associated with blood pressure (BP); this association has critical implications for countries like China, where hypertension highly prevalent and obesity increasing. A greater understanding of the between BMI BP required to determine its effect develop strategies mitigate it. <h3>Objective</h3> To assess heterogeneity in across a wide variety subgroups Chinese population. <h3>Design, Setting, Participants</h3> In cross-sectional study,...
Background Heart failure with preserved ejection fraction (HFpEF) remains an increasing public health problem substantial morbidity and mortality but few effective treatments. A novel inflammatory mechanism has been proposed, the signals promoting development of HFpEF remain greatly unknown. Methods Results Serum patients was collected for measurement circulating neutrophils markers neutrophil extracellular traps (NETs). To induce phenotype, male C57BL/6 mice underwent uninephrectomy,...
To assess the different educational inequalities in mortality among generations born between 1940 and 1979 China, to investigate role of socioeconomic, behavioural, metabolic factors as potential contributors reduction inequalities.Nationwide, population based, prospective cohort study.The ChinaHEART (China Health Evaluation And risk Reduction through nationwide Teamwork) project all 31 provinces mainland China.1 283 774 residents aged 35-75 years, divided into four separate cohorts 1940s,...
The triglyceride-glucose (TyG) index has been recognized as a crucial risk factor for cardiovascular diseases. However, the association between TyG and mortality in general population remains elusive.
Journal Article Cohort Profile: ChinaHEART (Health Evaluation And risk Reduction through nationwide Teamwork) Get access Runsi Wang, Wang National Clinical Research Center for Cardiovascular Diseases, NHC Key Laboratory of Medications, Fuwai Hospital, Chinese Academy Medical Sciences and Peking Union College, Beijing, People's Republic China Search other works by this author on: Oxford Academic PubMed Google Scholar Yang Yang, Jiapeng Lu, Lu Jianlan Cui, Cui Wei Xu, Xu Lijuan Song, Song...
Abstract Aims Pulsed field ablation (PFA) is an emerging non-thermal ablative modality demonstrating considerable promise for catheter of atrial fibrillation (AF). However, these PFA trials have almost universally included only Caucasian populations, with little data on its effect other races/ethnicities. The PLEASE-AF trial sought to study the 12-month efficacy and safety a multi-electrode hexaspline in treating predominantly Asian/Chinese population patients drug-refractory paroxysmal AF....
The chronic effects of fine particulate matter (PM2.5) at high concentrations remains uncertain. We aimed to examine the relationship long-term PM2.5 exposure with all-cause and top three causes death (cardiovascular disease [CVD], cancer, respiratory disease), analyze their concentration-response functions over a wide range concentrations.We enrolled community residents aged 35-75 years from 2014 2017 all 31 provinces Chinese Mainland, followed them up until 2021. used estimation dataset...
Background Intracavitary electrocardiogram (IC ECG) guidance emerges as a new technique for peripherally inserted central catheters (PICCs) placement and demonstrates many potential advantages in recent observational studies. Aims To determine whether IC ECG-guided PICCs provide more accurate positioning of catheter tips compared to conventional anatomical landmarks patients with cancer undergoing chemotherapy. Methods In this multicenter, open-label, randomized controlled study...
Trends in prevalence and treatments of atherosclerotic cardiovascular disease (ASCVD) remains to be documented, with frequent update relevant guidelines. We aimed characterize trends ASCVD, risk factor control medications among ASCVD adults.
Statins are extensively used for lowering LDL-cholesterol and reducing cardiovascular events. Recent studies have shown that statins beneficial anti-inflammatory effects. We aimed to determine whether how adipokines regulated during statin treatment in type 2 diabetic patients.In this study,we investigated the changes of CRP inflammation-related (SAA,IL-6,TNFalpha adiponectin) 23 patients with atherosclerosis who received therapy, 20 14 without did not receive therapy a period three...
China has been undergoing a rapid urbanisation. There are substantial disparities between old and new urban citizens in access to health care. We aimed compare cardiovascular disease prevention death risks among four distinct groups.Urban residents aged 35-75 years living 96 prefecture-level cities from 31 provinces mainland were enrolled the national population-based cohort Patient-centered Evaluative Assessment of Cardiac Events Million Persons Project. They categorised into groups by...
Abstract OBJECTIVE To investigate the relationship between body mass index (BMI) and risk of hypertension in elderly patients with dyslipidemia. METHODS Dyslipidemia aged 60 years above were selected from Tianjin surveillance points China Chronic Disease Surveillance (2019–2023). The data gender, age, height, blood pressure, BMI, disease history, other indicators collected through a cross-sectional survey. chi-square test multivariate logistic regression used to analyze influencing factors...
The aim of the current study was to identify biomarkers that correlate with Barcelona Clinic Liver Cancer (BCLC) staging system and prognosis patients hepatocellular carcinoma (HCC). We downloaded 4 gene expression datasets from Gene Expression Omnibus database (http://www.ncbi.nlm.nih.gov/geo), screened for genes were differentially expressed between HCC normal liver tissues, using significance analysis microarray algorithm. used a weighted co-expression network (WGCNA) hub BCLC staging,...
Abstract Dilated cardiomyopathy (DCM) is one of the leading causes heart failure. A large proportion genetic cause remains unexplained, especially in idiopathic DCM. We performed target next-generation sequencing 102 genes which were known or candidate for cardiomyopathies and channelpathies 118 prospectively recruited Han Chinese patients with 41 carried 40 pathogenic likely variants, providing a molecular diagnosis 34.7% patients. 32 these variants novel. TTN truncating predominant,...
Phyllodes tumors (PTs) has an increased risk of local relapse and distant metastases. Molecular features correlating to histologic grade aggressive behavior PTs are poorly characterized. Here, whole exome sequencing (WES) was performed explore genetic mutations in 61 samples fibroepithelial breast tumors, including 16 fibroadenomas (FAs), 18 benign PTs, 19 borderline 8 malignant PTs. Our work clearly shows that FA, PT, PT independent entities at the genomic level. They may exist as hidden...
Abstract Objectives The study aims to assess the effect of baseline glycated hemoglobin (HbA1c) levels on atrial fibrillation (AF) recurrence following cryoballoon ablation in patients with and without diabetes. Methods Consecutive AF receiving first between April 2018 2021 were included. other clinical outcomes recorded for a minimum 12 months post-ablation, regular assessments at 3, 6, months, followed by annual check-ups. primary outcome was after longest follow-up. Multivariate Cox...
Patient activity (PA) has been demonstrated to predict all-cause mortality. However, the association between PA and cardiac death is unclear. The aims of this study were determine whether can what cut-off discriminate death, as well mechanism underlying relationship survival in patients with home monitoring. This retrospectively analysed clinical implantable cardioverter-defibrillator/cardiac resynchronization therapy defibrillator device data 845 patients. Data regarding PP variability...
To investigate whether the use of continuous Pringle maneuver (PM) adversely impacts outcome patients with hepatocellular carcinoma (HCC).From January 1989 to 2011, 586 HCC who underwent curative resection in Peking Union Medical College Hospital were identified from database. Continuous PM was performed 290 (PM group), including 163 a hepatic inflow occlusion time <15 min (PM-1 group) and 127 15-30 (PM-2 group). An additional 296 partial hepatectomy without (occlusion-free, OF group).The...