A5100603155- Blood Pressure and Hypertension Studies
- Neuroblastoma Research and Treatments
- Animal Genetics and Reproduction
- RNA and protein synthesis mechanisms
- Diabetes, Cardiovascular Risks, and Lipoproteins
- DNA and Nucleic Acid Chemistry
- Advanced biosensing and bioanalysis techniques
- Cancer, Hypoxia, and Metabolism
- Renal and related cancers
- Viral Infectious Diseases and Gene Expression in Insects
- Virus-based gene therapy research
- RNA modifications and cancer
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Liver Disease Diagnosis and Treatment
- Photosynthetic Processes and Mechanisms
- RNA Interference and Gene Delivery
- Ideological and Political Education
- Per- and polyfluoroalkyl substances research
- Adsorption and biosorption for pollutant removal
- Aquaculture Nutrition and Growth
- Reproductive biology and impacts on aquatic species
- Plant tissue culture and regeneration
- Nanopore and Nanochannel Transport Studies
- Selenium in Biological Systems
TEDA International Cardiovascular Hospital
2020-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2024-2025
Henan University of Science and Technology
2008-2024
Tianjin University of Science and Technology
2021-2024
Capital Medical University
2009-2023
Beijing Tongren Hospital
2009-2023
Xinjiang Normal University
2016-2023
Shandong University
2023
Jiaxing University
2011-2022
Shandong Agricultural University
2013-2022
Methylated arsenic (As) species are a common constituent of rice grains accounting for 10-90% the total As. Recent studies have shown that higher plants unlikely to methylate As in vivo suggesting methylation is microbial mediated process occurs soils prior plant uptake. In this study, we designed primers according conserved essential amino acids and structural motifs arsenite S-adenosylmethionine methyltransferase (ArsM). We report first time successful amplification prokaryotic arsM gene...
To bridge the gap between sequences and 3-dimensional (3D) structures of RNAs, some computational models have been proposed for predicting RNA 3D structures. However, existed seldom consider conditions departing from room/body temperature high salt (1M NaCl), thus generally hardly predict thermodynamics effect. In this study, we propose a coarse-grained model with implicit RNAs to structures, stability, Combined Monte Carlo simulated annealing algorithm force field, folds 46 tested (≤45 nt)...
TP53, a tumor suppressor gene, plays critical role in cell cycle control, apoptosis, and DNA damage repair.Previous studies have indicated that the TP53 gene Arg72Pro (rs1042522 C>G) polymorphism is associated with susceptibility to various types of cancer.We evaluated association rs1042522 C>G neuroblastoma hospital-based study among Chinese Han population.Enrolled were 256 patients 531 controls.Odds ratios (ORs) 95% confidence intervals (CIs) generated using logistic regression models used...
<b><i>Aims:</i></b> Age-related lipofuscin N-retinylidene-N-retinylethanolamine (A2E) accumulated in human retinal pigment epithelium (RPE) cells confers susceptibility to blue light-mediated damage, which represents one pathogenesis of age-related macular degeneration. This study investigated the expression 2 best-characterized endoplasmic reticulum (ER) stress markers, glucose-related protein 78 (GRP78) and C/EBP homologous (CHOP), as well their regulation by...
Porous anodic aluminum oxide (AAO) Bragg stacks were fabricated by a modified two-step anodization, and the optical transmittance spectra of AAO soaking in varied analytes (air, series alcohols alkanes) collected. The results show that both wavelength intensity reflected light are sensitive to analyte's refractive index infiltration; e.g., for any two adjacent or alkanes, difference dip is greater than 3%. This phenomenon enables us fabricate chemical biological sensors situ monitor organic...
This study aimed to characterize the clinical features, genetic findings, and genotype-phenotype correlations of patients with Leber congenital amaurosis (LCA) or early-onset severe retinal dystrophy (EOSRD) harboring biallelic AIPL1 pathogenic variants.
Nucleic acids are negatively charged macromolecules and their structure properties strongly coupled to metal ions in solutions. In this article, the salt effects on flexibility of single‐stranded (ss) nucleic acid chain ranging from 12 120 nucleotides investigated systematically by coarse‐grained Monte Carlo simulations where considered explicitly ss is modeled with virtual‐bond structural model. Our calculations show that, increase ion concentration causes collapse multivalent much more...
Previous genome-wide association studies (GWASs) have reported that three single nucleotide polymorphisms (SNPs) (rs6939340 A>G, rs4712653 T>C, and rs9295536 C>A) located at 6p22 locus were associated with neuroblastoma susceptibility for Caucasian descent. We conducted this hospital-based case-control study 201 patients 531 controls to investigate the between these SNPs in FLJ22536 gene Chinese Han population. The odds ratio (OR) 95 % confidence interval (CI) calculated estimate strength of...
Objectives We estimated the prevalence of metabolic syndrome (MetS) and compared associations different MetS definitions with coronary heart disease (CHD), stroke, peripheral arterial (PAD) in a rural Chinese population. Methods Among 4,748 residents (2,145 men 2,603 women) aged 30+ years China from 2006 to 2007, was by using five definitions: modified World Health Organization (WHO), Diabetes Society (CDS), updated National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP...
// Jing He 1, 2, * , Wei Zhong Jixiao Zeng Jinhong Zhu 3 Ruizhong Zhang 1 Fenghua Wang Tianyou Yang Yan Zou Huimin Xia Department of Pediatric Surgery, Guangzhou Institute Pediatrics, Women and Children's Medical Center, University, 510623, Guangdong, China 2 Sun Yat-Sen University Cancer State Key Laboratory Oncology in South China, Experimental Research, Collaborative Innovation Center for Medicine, 510060, Molecular Epidemiology Harbin Hospital, 150040, Heilongjiang, These authors...
To study the differences in ophthalmology resident training between China and Hong Kong Special Administrative Region (HKSAR).Training programs were selected from among largest best-known teaching hospitals. Ophthalmology residents sent an anonymous 48-item questionnaire by mail. Work satisfaction, time allocation activities volume of surgery performed determined.50/75 (66.7 %) 20/26 (76.9 HKSAR completed survey. Age (28.9 ± 2.5 vs. 30.2 2.9 years, p = 0.15) number years (3.4 1.6 2.8 1.5,...