A5048563205- Electrolyte and hormonal disorders
- Potassium and Related Disorders
- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Ion Transport and Channel Regulation
- Renal function and acid-base balance
- Chronic Kidney Disease and Diabetes
- Parathyroid Disorders and Treatments
- Blood Pressure and Hypertension Studies
- Neurological and metabolic disorders
- Neurological Disease Mechanisms and Treatments
- Biomedical Research and Pathophysiology
- Pharmacological Effects and Toxicity Studies
- Acute Kidney Injury Research
- Nephrotoxicity and Medicinal Plants
- Renal and Vascular Pathologies
- Central Venous Catheters and Hemodialysis
- Nutritional Studies and Diet
- Retinal Diseases and Treatments
- Gastrointestinal disorders and treatments
- Peripheral Artery Disease Management
- Congenital Heart Disease Studies
- Apelin-related biomedical research
- Liver Disease Diagnosis and Treatment
- Financial Distress and Bankruptcy Prediction
University of Suwon
2025
Hanyang University Guri Hospital
2015-2024
Birkbeck, University of London
2024
Seoul National University
2013-2024
Government of the Republic of Korea
2023
Hanyang University
2008-2022
Beijing Sanbo Brain Hospital
2020
Capital Medical University
2020
Soongsil University
2019
University of Michigan
2015
Diabetic nephropathy is the most frequent cause of end-stage renal disease worldwide. Dialysis patients with diabetes mellitus (DM) have more complications and shorter survival duration than non-DM dialysis patients, requiring clinical attention difficult management. The registry committee Korean Society Nephrology has collected data about therapy in Korea through an on-line program analyzed characteristics patients. A survey 2016 showed that 50.2% new had DM as disease. proportion receiving...
Heavy proteinuria with or without features of nephrotic syndrome is associated many primary and systemic diseases. For diabetic patients, distinguishing nondiabetic renal disease (NDRD) from nephropathy (DN) important in choosing treatment modalities determining prognosis. However, clinical relevance heavy inconsistent DN assessments. This study investigated the clinicopathological outcomes NDRD type 2 patients nephrotic-range proteinuria. We enrolled 220 cases who underwent biopsy. They...
Abstract The purpose of this study is to evaluate the effect haemodialysis on perfused vessel density, choroidal thickness (CT), and retinal in end-stage renal disease (ESRD) using swept-source optical coherence tomography angiography (SS-OCTA). We studied twenty-nine eyes 29 ESRD patients by ophthalmologic examination SS-OCTA before after haemodialysis. colour-coded perfusion density maps were generated was calculated. Changes systemic other ocular parameters such as measured analysed....
There have been controversies in prognostic impact of mucinous histology on colorectal cancer, and its implication patients treated with adjuvant 5-fluorouracil, leucovorin, oxaliplatin (FOLFOX) is unclear. Stage II III cancer who underwent curative resection followed by FOLFOX were included. Patients grouped according to the content: >50%, adenocarcinoma (MAC); <50%, intermediated component (AIM); without any component, non-MAC (NMA). Clinicopathological features disease-free survival (DFS)...
Background. Renin–angiotensin system (RAS) blockades, angiotensin converting enzyme inhibitors (ACEIs) and II receptor blockers (ARBs) are well accepted for the cardiorenal-protective benefits added to antihypertensive effects in chronic kidney diseases (CKD), but associated with an increased risk of hyperkalaemia. However, few studies have investigated effect RAS blockades on serum potassium dialysis patients. Methods. Hyperkalaemia by ACEI and/or ARB was evaluated 69 patients maintenance...
In many countries, nephrologists follow clinical practice guidelines for mineral bone disorders to control secondary hyperparathyroidism (SHPT) associated with abnormal serum calcium (Ca) and phosphorus (P) levels in patients undergoing maintenance hemodialysis (MHD). The Kidney Disease Outcomes Quality Initiative (KDOQI) Guidelines have long been used Korea, this study was undertaken investigate the current status of Ca P MHD patients. Data were collected from a total 1,018 without...
Abstract To evaluate the effect of hemodialysis on choroidal thickness and vascularity index (CVI) in patients with end-stage renal disease (ESRD) by using swept-source optical coherence tomography. Thirty-two eyes 32 ESRD undergoing were recruited prospectively. Detailed ophthalmologic examinations tomography performed immediately before after hemodialysis. Choroidal maps generated automatically built-in software. The CVI was calculated binarized images. Systemic parameters such as body...
Interstitial fibrosis and tubular atrophy (IFTA) is a well-recognized risk factor for poor renal outcome in patients with diabetic kidney disease (DKD). However, noninvasive biomarker IFTA currently lacking. The purpose of this study was to identify urinary markers determine their clinical relevance as predictors prognosis.Seventy biopsy-proven isolated DKD were enrolled study. We measured multiple inflammatory cytokines chemokines by multiplex enzyme-linked immunosorbent assay these...
Coronavirus disease 2019 (COVID-19) is one of the most widespread viral infections in human history. As a breakthrough against infection, vaccines have been developed to achieve herd immunity. Here, we report first case microscopic polyangiitis (MPA) following BNT162b2 vaccination Korea. A 42-year-old man presented emergency room with general weakness, dyspnea, and edema after second vaccination. He had no medical history other than being treated for tuberculosis last year. Although his...
Polycystic kidney disease (PKD) typically manifests as genetic disease, which is commonly attributed to mutations in <i>PKD</i> genes. In this particular case, however, analysis revealed that the patient’s PKD linked a novel, likely pathogenic variant (c.2184del; p.Thr729Leufs*88) oral-facial-digital syndrome type I (<i>OFD1</i>) gene. This first confirmed diagnosis of <i>OFD1</i> gene Korea. investigation emphasizes critical utility panel sequencing...
Abstract The Basel Accord emphasizes the necessity of employing internal data models to manage key credit risk components, including Probability Default (PD), Loss Given (LGD), and Exposure At (EAD). Among these, datasets are critical for estimating PD, a fundamental measure borrower creditworthiness. Nevertheless, practical application often faces challenges due incomplete datasets, which can skew analyses undermine accuracy scoring models. Traditional approaches addressing missing data,...
<b><i>Background: </i></b>Chronic kidney disease (CKD) patients are prone to both hypo- and hypernatremia. Little has been published on the epidemiology of hypernatremia in ambulatory with non-dialysis CKD. <b><i>Methods:</i></b> Data collected two contemporaneous CKD cohort studies, Renal Research Institute (RRI)-CKD study (n = 834) Study Treatment Insufficiency: Evaluation (STRIDE) 1,348) were combined analyzed association between serum...
Kruppel-like factor 2 (KLF2) regulates endothelial cell metabolism; dysfunction is associated with hypertension and a predictor of atherosclerosis development cardiovascular events. Here, we investigated the role KLF2 in hypertensive nephropathy by regulating expression human primary glomerular cells (hPGECs) evaluating this kidney tissues 5/6 nephrectomy mouse model as well patients hypertension. Hypertension-mimicking devices siRNA were used to downregulate expression, while was...
This is a case of sudden cardio-pulmonary arrest in 29 year-old female, which occurred immediately after large bolus infusion propofol (100 mg) intravenously during dilatation and curettage. The suddenly occurred, the patient was eventually transferred to our emergency room (ER) on cardiopulmonary resuscitation. At that time, severe hyperkalemia up 9.1 mEq/L ventricular fibrillation were noted. Resuscitation ER worked successfully with conversion electrocardiograph sinus rhythm, but this...
Prolonged hypokalemia from chronic laxative abuse is recognized as the cause of tubulointerstitial disease, known "hypokalemic nephropathy," but it not clear whether contributes to acute kidney injury (AKI). A 42-year-old woman with a history disease result purging type anorexia nervosa (AN-P), developed an anuric AKI requiring hemodialysis and mild 2 months later. Both episodes involved severe moderate (1.2 2.7 mmol/L, respectively), volume depletion, rhabdomyolysis. The histologic findings...
We report a rare case of the concurrent manifestation central diabetes insipidus (CDI) and type 2 mellitus (DM). A 56 year-old man was diagnosed as DM on basis hyperglycemia with polyuria polydipsia at local clinic two months ago started an oral hypoglycemic medication, but resulted in no symptomatic improvement all. Upon admission to university hospital, patient's initial fasting blood sugar level 140 mg/dL, he showed polydipsic polyuric conditions more than 8 L urine/day. Despite...
Ultrasound-guided cannulation of a large-bore catheter into the internal jugular vein was performed to provide temporary hemodialysis vascular access for uremia in 65-yr-old woman with acute renal failure and sepsis superimposed on chronic failure.Despite absence any clinical evidence such as bleeding or hematoma during procedure, chest x-ray computed tomographic angiogram neck showed that had inadvertently been inserted subclavian artery.Without immediately removing applying manual external...
The patency of arteriovenous access is important for stable and effective hemodialysis, long-term technical survival best achieved with a native fistula (AVF). However, maintaining AVF remains challenge. This study was designed to determine the independent prognostic factors according hemodialysis duration. primary end point unassisted AVF, which defined as time from first surgery failure. failure an event that required percutaneous intervention or revise replace fistula, occurred at least 2...