A5029941683- Air Quality and Health Impacts
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Infection Control and Ventilation
- Climate Change and Health Impacts
- COVID-19 and healthcare impacts
- Inflammasome and immune disorders
- Cancer-related molecular mechanisms research
- Fatty Acid Research and Health
- Heme Oxygenase-1 and Carbon Monoxide
- Effects and risks of endocrine disrupting chemicals
- Air Quality Monitoring and Forecasting
- interferon and immune responses
- Carcinogens and Genotoxicity Assessment
- Energy and Environment Impacts
- Eicosanoids and Hypertension Pharmacology
- Heavy Metal Exposure and Toxicity
- Chromatography in Natural Products
- Nanoparticles: synthesis and applications
- Toxic Organic Pollutants Impact
- Sesquiterpenes and Asteraceae Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Redox biology and oxidative stress
- Semiconductor materials and devices
- Chronic Obstructive Pulmonary Disease (COPD) Research
Jiangxi University of Traditional Chinese Medicine
2011-2025
Shanxi Academy of Medical Sciences
2025
Shanxi Medical University
2025
Chengdu University of Traditional Chinese Medicine
2025
Oak Ridge Associated Universities
2019-2024
Guangxi Medical University
2020-2024
Shandong Normal University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2024
Peking Union Medical College Hospital
2024
Union Hospital
2024
Hydrogen polysulfides (H2Sn, n > 1), derived from hydrogen sulfide (H2S), have attracted increasing attention in biochemical research, which may perform as the actual signaling molecules during cell processes. Because of closed biological and chemical relationship between H2S H2Sn, it is great value to develop sensitive specific techniques distinguish intracellular level H2Sn. To improve understanding physiological pathological roles played by we now a fluorescent probe Mito-ss for capturing...
Procuring respiratory protection for clinicians and other health care workers has become a major challenge of the coronavirus disease 2019 (COVID-19) pandemic resulted in nonstandard practices such as use expired respirators various decontamination processes to prolong useful life settings. In addition, imported, non-National Institute Occupational Safety Health (NIOSH)-approved have been donated or acquired by hospitals potential replacement limited NIOSH-approved N95 respirators.
Abstract Gasdermin D (GSDMD)-mediated pyroptosis has a significant pro-inflammation characteristic due to dramatic secretion of pro-inflammatory substances. However, its role remains unclear in psoriasis as one chronic inflammatory skin disorder with high prevalence. We found that N-terminal GSDMD (N-GSDMD) was aberrantly expressed epidermis lesion patients and imiquimod-induced psoriasis-like dermatitis (IIPLD) mice. In IIPLD mice M5 (simulating psoriatic challenge)-treated keratinocytes...
As one of the most important food and feed crops worldwide, maize suffers much more tremendous damages under heat stress compared to other plants, which seriously inhibits plant growth reduces productivity. To mitigate heat-induced adapt high temperature environment, plants have evolved a series molecular mechanisms sense, respond temperatures stress. In this review, we summarized recent advances in regulations underlying sensing, response memory maize, especially focusing on several...
Exposure to air pollution is associated with elevated cardiovascular risk. Evidence shows that omega-3 polyunsaturated fatty acids (omega-3 PUFA) may attenuate the adverse effects of exposure fine particulate matter (PM2.5). However, it unclear whether habitual dietary intake PUFA protects against short-term low-level ambient in healthy participants. In present study, sixty-two adults low or high were enrolled. Blood lipids, markers vascular inflammation, coagulation and fibrinolysis, heart...
Inflammatory caspases sensing lipopolysaccharide (LPS) to drive gasdermin (GSDM)–mediated pyroptosis is an important immune response mechanism for anti-infection defense in mammals. In this work, we resolved LPS-induced and GSDM-gated signaling cascade Cnidarians. Initially, identified a functional GSDM protein, HyGSDME, Hydra , executing cytosolic caspase-dependent manner. Further, proinflammatory caspase, HyCaspA capable of LPS by uncharacterized N-terminal domain relying on its unique...
This quality improvement study compares the fitted filtration efficiency of commonly available face masks worn singly, doubled, or in combinations.
Globally, a large percentage of men keep beard at least occasionally. Workplace regulations prohibit beards with N95 respirators, but there is little information on the effect face masks worn by public for protection against SARS-CoV-2.We examined fitted filtration efficiency (FFE) five commonly protective as function length following US Occupational Safety and Health Administration Quantitative Fit Test: (respirator), KF94 KN95, surgical/procedure, cloth masks. A comparison using...
Abstract Objective Microglial polarization plays a critical role in neuroinflammation and may be potential therapeutic target for ischemic stroke. This study was to explore the underlying molecular mechanism of Circular RNA PTP4A2 (circPTP4A2) microglial after Methods C57BL/6J mice underwent transient middle cerebral artery occlusion (tMCAO), while primary mouse microglia BV2 cells experienced oxygen glucose deprivation/reperfusion (OGD/R) mimic conditions. CircPTP4A2 shRNA lentivirus...
Resistant hypertension (RHTN), a clinically complex condition with profound health implications, necessitates considerable time and allocation of medical resources for effective management. Unraveling the environmental risk factors associated RHTN may shed light on future interventional targets aimed at reducing its incidence. Exposure to heavy metal has been linked an increased hypertension, while relationship remains poorly understood.Using 1999-2018 National Health Nutrition Examination...
Circular RNAs (circRNAs) are known to play an important role in the regulation of gene expression eukaryotes. Photo-thermosensitive genic male sterile (PTGMS) is a very germplasm resource two-line hybrid rice breeding. Although many circRNAs have been identified (Oryza sativa L.), little about biological roles fertility transition PTGMS line.In present study, RNA-sequencing libraries were constructed from young panicles Wuxiang S line (WXS (S)) and its fertile (F)) at three development...
Circular RNAs (circRNAs) contribute to multiple biological functions and are also involved in pathological conditions such as cancer. However, the role of circRNAs metabolic reprogramming, especially upon energy stress lung adenocarcinoma (LUAD), remains largely unknown. Energy stress-induced circRNA was screened by profiling glucose deprivation assays. RNA-seq, real-time cell analyzer system (RTCA) measurement oxygen consumption rate (OCR) were performed explore circZFR LUAD. The underlying...