Many studies have reported the effect of hypertension on microcirculation retina. Advance optical coherence tomography angiography (OCTA) allows us more detailed observations Therefore, we compared OCTA parameters between chronic (disease duration at least 10 yrs; Group A, 45 eyes), relieved hypertensive retinopathy (grade IV HTNR < 1 yr prior; B, 40 and normal controls [Group C (50 eyes) ≥ 50 yrs old D old]. A 3 × mm macular scan was performed in each group by OCTA. In vessel density full,...

The quality of the scan image is important in microvascular circulation analysis using optical coherence tomography (OCTA). We aimed to investigate effect signal strength (SS) on OCTA metrics and minimum SS level that could be considered optimal. Macular 6 × mm angiography images were acquired, all subjects divided into four groups according (SS 7, 8, 9, 10) image. Vessel density (VD), perfusion (PD), foveal avascular zone (FAZ) superficial capillary plexus compared. In total, 446 eyes from...

To investigate the difference in occurrence of postoperative epiretinal membranes (ERMs) vitrectomy for rhegmatogenous retinal detachment with and without peeling internal limiting membrane (ILM).The medical records 135 patients, who underwent primary from November 2007 to August 2011, were analyzed retrospectively. Of subjects, 70 patients ILM during surgery 65 did not. The best-corrected visual acuity, fundus photograph, optical coherence tomography collected 3, 6, 12 months...

Type 2 diabetes is expected to accelerate age-related peripapillary retinal nerve fiber layer (pRNFL) loss, but limited information on the rate of reduction in pRNFL thicknesses patients with type available.To investigate longitudinal changes thickness diabetes, or without diabetic retinopathy (DR).A total 164 eyes 63 healthy individuals and 101 (49 DR [non-DR group] 52 mild moderate nonproliferative [NPDR group]) were enrolled this prospective, longitudinal, observational study from January...

Aim To determine the longitudinal changes in axial length (AL) patients with high myopia without any other ophthalmic disease Methods Participants were divided into two groups: a group (60 eyes) myopic degeneration, such as chorioretinal atrophy or posterior staphyloma, and control eyes). Both groups further subgroups according to AL: subgroup 1 (≥27.5 mm), 2 (26.0–27.5 3 (24.5–26.0 mm) 4 (&lt;24.5 mm). The ALs measured five times at 1-year interval using an IOL master, AL was fitted linear...

Abstract To evaluate changes in peripapillary microvascular parameters diabetes mellitus (DM) patients using optical coherence tomography angiography (OCTA). Seventy-one diabetic (40 the no retinopathy [DR] group and 31 non-proliferative DR [NPDR] group) 50 control subjects. OCTA (Zeiss HD-OCT 5000 with AngioPlex) 6 × mm scans centered on optic disc were analyzed. Peripapillary vessel density (VD), perfusion (PD) superficial capillary plexus (SCP) automatically calculated. The average...

Substitution of white with orange fleshed varieties sweet potatoes (OFSP) was recently shown to alleviate vitamin A deficiency in children Africa. However, the relationship between β-carotene (BC) content different cultivars OFSP and its bioavailability is unknown. Here, we used three phase (oral, gastric small intestinal) vitro digestion procedure examine bioaccessibility BC from eight boiled OFSP. All-trans (all-E-BC) only isomer detected raw roots for amounts ranging 112 281 μg/g. Boiling...

Purpose: To evaluate changes in peripapillary microvascular parameters the fellow eyes of patients with unilateral retinal vein occlusion (RVO) using optical coherence tomography angiography (OCTA) and to determine relationships between microvasculature nerve fiber layer (RNFL) ganglion cell-inner plexiform (GC-IPL) thickness. Methods: Eighty-three RVO (50 branch 33 central RVO) 83 normal controls were enrolled. OCTA (Cirrus HD-OCT 5000 AngioPlex) 6 × 6-mm scans centered on optic disc...

Abstract Diabetes is expected to accelerate age-related ganglion cell–inner plexiform layer (GC-IPL) loss, but there limited information on the rate of reduction in GC-IPL thicknesses. We aimed evaluate thickness diabetic patients, and compare rates between patients without with retinopathy (DR). included 112 eyes diabetes [49 DR (no-DR group) 63 mild moderate non-proliferative (NPDR group)] normal controls (control this study. Macular all participants was measured for 3 years at 1-year...

To analyze longitudinal changes in the retinal nerve fiber layer (RNFL) thickness branch vein occlusion (BRVO) using optical coherence tomography.The authors prospectively analyzed 20 eyes patients diagnosed with and followed for more than 1 year. The RNFL of normal occluded was measured at time diagnosis 1, 3, 6, 12 months. compared eye over follow-up differences between two each time. They also area opposite area.The BRVO significantly reduced months (P = 0.005 month P 0.001 months)...

Nam, Ki Y. MD; Kim, Woo J. Jo, Young Jung MDEditor(s): Williams, George A. Author Information

To investigate the relationship between spectral-domain optical coherence tomography (SD-OCT) measurements and retinal nonperfusion in patients with branch vein occlusion (BRVO).Forty-one BRVO who had recovered from macular edema been followed for ≥2 years were included via retrospective, medical record review. Patients divided into two groups that 20 nonischemic eyes 21 ischemic eyes, 41 fellow control also included. Using SD-OCT, we measured thickness of layer, ganglion cell-inner...

To compare retinal thickness between patients with chronic hypertension without retinopathy, hypertensive Keith-Wagener-Barker Grade IV status, and normal controls using spectral domain optical coherence tomography.In this retrospective study, we analyzed who visited our clinic from January 2013 to February 2016. Of those included, 58 eyes of were in the healthy control group (Group A), 37 retinopathy (disease duration at least 10 years; Group B), 31 relieved (Grade a year or more ago but no...

Aim To analyse the repeatability of vessel density (VD) measurements using optical coherence tomography angiography (OCTA) in patients with retinal diseases. Methods Two consecutive VD OCTA were analysed prospectively diseases (diabetic macular oedema (DME), vein occlusion (RVO) oedema, epiretinal membrane (ERM), wet age-related degeneration (AMD)). The intraclass correlation coefficient (ICC), variation (CV) and test-retest SD assessed, linear regression analyses conducted to identify...

To identify the effects of prolonged type 2 diabetes (T2DM) on macular microcirculation and inner retinal layer in diabetic eyes without clinical retinopathy (DR).97, 92, 57 control, patients with T2DM < 10 years (DM group one), ≥ two) were enrolled. The ganglion cell-inner plexiform (GC-IPL) thickness superficial vessel density (VD) compared. Linear regression analyses performed to factors associated VD patients.GC-IPL thicknesses DM one, two 84.58 ± 0.89, 83.49 0.70, 79.04 0.96 μm,...

In Brief Purpose: To investigate longitudinal changes in retinal nerve fiber layer (RNFL) thickness after panretinal photocoagulation (PRP) diabetic retinopathy patients. Methods: This prospective study examined 31 eyes 25 patients undergoing PRP, who were diagnosed with severe nonproliferative or non–high-risk proliferative retinopathy. Optical coherence tomography was conducted before PRP and at 3, 6, 12, 24 months to peripapillary RNFL thickness. Results: Superior, nasal, inferior,...

In Brief Purpose: The purpose of this study was to investigate changes in macular thickness after panretinal photocoagulation (PRP) patients with severe diabetic retinopathy (DR) without edema and compare the visual acuity outcomes. Methods: This prospective cohort included 30 nonproliferative DR or non–high-risk proliferative whose ≥0.8 before PRP. Sixty eyes received biweekly PRP treatment 4 sessions. Macular were measured at 1, 3, 6, 12 months Results: acuities 0.02 ± 0.11 0.04 0.11,...

Purpose.: We investigated longitudinal changes in retinal nerve fiber layer (RNFL) thickness following vitrectomy for epiretinal membrane (ERM). Methods.: Thirty-one patients who underwent pars plana with internal limiting (ILM) peeling ERM were included. Average and four quadrants of RNFL thicknesses determined before at 1, 3, 6, 12 months after surgery by spectral-domain optical coherence tomography (SD-OCT). As macular lesions could affect thickness, we evaluated dividing the into o'clock...

To analyze the repeatability of measurements thicknesses macula, retinal nerve fiber layer (RNFL), and ganglion cell inner plexiform (GCIPL) using spectral-domain optical coherence tomography (SD-OCT) in epiretinal membrane (ERM).The prospective study analyzed patients who visited our clinic from June 2013 to January 2014. An experienced examiner measured twice macular cube 512 × 128 optic disc 200 scans. The RNFL, GCIPL were compared intraclass correlation coefficient (ICC) two groups based...

Abstract The quality of the scan image is important in peripapillary circulation analysis using optical coherence tomography angiography (OCTA). We aimed to investigate effects signal strength (SS) on microvascular density acquired from OCTA. A total 259 eyes young healthy subjects were included. Peripapillary OCTA images 3 × mm all participants. Subjects divided into four groups according SS: SS 7, 8, 9, and 10. Vessel (VD) perfusion (PD) superficial capillary plexus calculated. VD PD...

Purpose: To determine longitudinal changes in the peripapillary retinal nerve fiber layer (pRNFL) thickness patients with hypertension (HTN). Methods: Participants without any ophthalmic disease were divided into two groups: an HTN group (50 eyes) that included for ≥5 years and a control group. After initial visit, pRNFL thicknesses measured four more times at 1-year intervals using spectral-domain optical coherence tomography. The was fitted linear mixed models. Univariate multivariate...

Abstract Various factors can affect repeatability of optical coherence tomography angiography (OCTA) measurements, and they have not been studied sufficiently. We aimed to investigate the associated with automated superficial retinal vessel density (VD) foveal avascular zone (FAZ) metrics acquired from OCTA. A total 141 normal eyes healthy subjects were included, two consecutive macular 6 × 6-mm scans performed. VD, perfusion (PD), FAZ capillary plexus calculated automatically....