A5014403719- Thyroid and Parathyroid Surgery
- Thyroid Cancer Diagnosis and Treatment
- Head and Neck Anomalies
- Nitric Oxide and Endothelin Effects
- Mitochondrial Function and Pathology
- Salivary Gland Tumors Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Electron Spin Resonance Studies
- Meningioma and schwannoma management
- Genetic Syndromes and Imprinting
- Neurological Disease Mechanisms and Treatments
- Artificial Intelligence in Healthcare and Education
- Radiomics and Machine Learning in Medical Imaging
- Appendicitis Diagnosis and Management
- S100 Proteins and Annexins
- Innovations in Medical Education
- Thyroid Disorders and Treatments
- Nerve Injury and Rehabilitation
- Renin-Angiotensin System Studies
- Peroxisome Proliferator-Activated Receptors
- Metabolomics and Mass Spectrometry Studies
- Surgical Simulation and Training
- Health and Medical Research Impacts
- Neurological Disorders and Treatments
- Hernia repair and management
Tulane University
2019-2025
Louisiana State University Health Sciences Center New Orleans
2024
Background/Objectives: Research is widely recognized as an essential element of medical education across all levels. This study explores the association between publishing before, during, and after general surgery residency, shedding light on research productivity trends in education. By examining a diverse cohort residents, aims to uncover factors influencing output at various training Methods: analyzed graduates’ Curriculum Vitae from single institution’s residency program 2017–2024....
Nitric oxide (NO) is known to exert inhibitory control on mitochondrial respiration in the heart and brain. Evidence supports presence of NO synthase (NOS) mitochondria (mtNOS) cells; however, functional role mtNOS regulation unclear. Our objective was examine effect NOS inhibitors protein S-nitrosylation. Freshly isolated cardiac brain nonsynaptosomal were incubated with selective neuronal (nNOS; ARL-17477, 1 µmol/L) or endothelial [eNOS; N5-(1-iminoethyl)-l-ornithine, NIO, µmol/L]...
Radiofrequency ablation is a minimally invasive treatment for thyroid nodules; however, concerns exist regarding its impact on subsequent surgery. We compared surgical outcomes and complications between patients undergoing thyroidectomy after radiofrequency (post-radiofrequency group) those without prior (non-radiofrequency group).
Peroxynitrite (PN), generated from the reaction of nitric oxide (NO) and superoxide, is implicated in pathogenesis ischemic neurodegenerative brain injuries. Mitochondria produce NO mitochondrial synthases superoxide by electron transport chain. Our objective was to detect generation PN origin characterize its effects on respiratory function. Freshly isolated nonsynaptosomal mitochondria C57Bl/6 (wild type, WT) endothelial synthase knockout (eNOS-KO) mice were treated with exogenous (0.1, 1,...
The risk of complication in patients undergoing completion thyroidectomy (cT) is mixed. Several studies report increased comparison to total (TT) and still others reporting a comparatively decreased risk. We compared the rates at our institution thyroid lobectomy (TL), (TT), cT by single high-volume surgeon.
Fine-needle aspiration (FNA) is the standard form of preoperative evaluation thyroid nodule cytological status. A significant number FNAs are classified as inadequate for interpretation, requiring a repeat FNA which potentially avoidable, costly, and delays treatment. To address these concerns maximize first-time adequacy, rapid onsite (ROSE) specimens was introduced. Our study aims to determine impact ROSE on adequacy.
Patients with complicated appendicitis have an increased risk for postoperative infections. Potential factors infections through a meta-analysis and retrospective chart review are discussed. A consisting of 35 studies analyzing treated appendectomy noting at least 1 infection was performed. then conducted in patients diagnosed after appendectomy. Of 5326 total, 15.4% developed Laparoscopic surgery perioperative hyperoxygenation were found to be protective the development infection....
While the route, location, and pathology of lingual nerve has been detailed extensively in reports literature, its terminal branch to sublingual gland is often overlooked. It known, via both gross histological observation, that glandular terminates at posterior aspect gland. Upon routine cadaveric dissection a male cadaver, one branches was found terminate anteroinferior portion herniated This specific course not previously discussed or reported observation. Therefore, timely review nerve's...
Background: Inhibition nitric oxide synthase (NOS) has been shown to paradoxically protect against ischemic brain injury by an unknown mechanism. Recently, we found that NOS inhibitor, N (gamma)-nitro-L-arginine methyl ester (L-NAME), protects primary cultures of endothelial cells and neurons oxygen-glucose deprivation-reoxygenation preventing uncoupling. Thus, the objective present study was demonstrate effectiveness locally administered L-NAME ischemia-reperfusion (I-R) injury. Methods:...
Objective Peroxynitrite, generated from nitric oxide and superoxide, plays a pathological role in both ischemic neurodegenerative brain injury. Mitochondrial dysfunction is key initiator of cerebrovascular neurological pathologies. Thus, understanding the acute effects peroxynitrite on mitochondrial physiology will help identify potential therapeutic targets. The objective study was to investigate impact respiratory function membrane isolated murine mitochondria. Methods Mitochondria were...
Objective Peroxynitrite, generated from nitric oxide and superoxide, plays a pathological role in both ischemic neurodegenerative brain injury. Free radical mediated microvascular dysfunction is key initiator of cerebrovascular neurological pathologies. Thus, understanding the acute effects peroxynitrite on microvessels will help identify potential therapeutic targets. The objective study was to investigate impact scavenger nitrotyrosination S‐nitrosylation microvessels. Methods Brain were...
Objective Aging is associated with an increased risk of neurodegenerative diseases and stroke. Impaired microvascular function was proposed to be the connecting link, but underlying mechanisms are unclear. Microvasculature critical for cerebrovascular blood flow, neurovascular coupling, nutrient transport, blood‐brain‐barrier. Maintaining these energy‐demanding functions by cerebral microvasculature needs optimal functioning energy pathways like glycolysis mitochondrial respiration....