A5088450356- Parasitic Infections and Diagnostics
- Amoebic Infections and Treatments
- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Insect and Pesticide Research
- SARS-CoV-2 and COVID-19 Research
- Mosquito-borne diseases and control
- Insects and Parasite Interactions
- Coccidia and coccidiosis research
- Animal Virus Infections Studies
- Parasitic infections in humans and animals
- Diagnosis and treatment of tuberculosis
- Aquaculture disease management and microbiota
- Bird parasitology and diseases
- Mycobacterium research and diagnosis
- Appendicitis Diagnosis and Management
- Pancreatitis Pathology and Treatment
- Malaria Research and Control
- Virus-based gene therapy research
- HIV Research and Treatment
- SARS-CoV-2 detection and testing
- Viral gastroenteritis research and epidemiology
- Genomics and Phylogenetic Studies
- Bacterial biofilms and quorum sensing
- Legionella and Acanthamoeba research
Kanazawa University
2015-2025
Kenya Medical Research Institute
2015-2016
Jaramogi Oginga Odinga University of Science and Technology
2015
A cross-sectional molecular epidemiological study of Giardia intestinalis infection was conducted among asymptomatic Kenyan children with (n = 123) and without 111) HIV infection. G. assemblage B positively correlated [HIV (+), 18.7% vs. (−), 11.7%; P 0.013], whereas not 4.1% 6.3%; 0.510]. Thus, is a risk factor for but
Viral vectors are a potent vaccine platform for inducing humoral and T-cell immune responses. Among the various viral vectors, replication-competent ones less commonly used coronavirus disease 2019 (COVID-19) development compared with replication-deficient ones. Here, we show availability of smallpox LC16m8Δ (m8Δ) as vector COVID-19 vaccine. M8Δ is genetically stable variant licensed highly effective Japanese LC16m8. generated two m8Δ recombinants: one harbouring gene cassette encoding...
A cross-sectional molecular epidemiological study of Entamoeba species was conducted among asymptomatic Kenyan children with (n = 123) and without 111) HIV infection. The prevalence E. histolytica low (0.4%). infection inversely related [HIV(+): 29.3% vs.55.0%, P < 0.001]: multiple-species to higher CD4 T-cell counts. Thus, is not a risk factor for amebic infection, can be an indicator better immune status.
Although parasites are still endemic in developing areas, residents those regions seem not to be affected by the presence of intestinal protozoans. This study aimed investigate whether pathogenic and commensal protozoans causal agents diarrhea via a school-based cross-sectional survey conducted Indonesia, September 2016. Molecular screening for collected 144 stool samples from healthy students (age range 7–15 years) was carried out. The prevalence protozoan as follows: Giardia intestinalis...
An 82-year-old man, who was healthy and had worked as a farmer, experienced worsening neurological symptoms over seven-month period, which eventually caused his death. Multiple fluctuating brain lesions were detected radiographically. Clinically, sarcoidosis ranked high among the differential diagnoses because of presence skin showing granulomatous inflammation, confirmed by biopsy. The patient's cerebrospinal fluid also examined, but no definitive diagnosis made while he alive. autopsy...
It has been reported that HIV infection is not a risk factor for Entamoeba species but Giardia intestinalis assemblage B in children living Western Kenya. This study aimed to investigate the prevalence of and factors spp. G. Nairobi, cross-sectional included 87 with [HIV(+)] 85 without [HIV(-)]. Stool blood samples were collected detection parasites by PCR immunological analyses using flow cytometry. Sociobehavioral hygienic data questionnaires analyzed statistically. The was significantly...
The Malaria Vaccine Technology Roadmap 2013 (World Health Organization) aims to develop safe and effective vaccines by 2030 that will offer at least 75% protective efficacy against clinical malaria reduce parasite transmission. Here, we demonstrate a highly multistage vaccine both the pre-erythrocytic sexual stages of Plasmodium falciparum protects reduces transmission in murine model. is based on viral-vectored platform, comprising highly-attenuated vaccinia virus strain, LC16m8Δ (m8Δ),...
Diseases caused by beetle larvae infestation are known as intestinal canthariasis. Canthariasis from the cigarette beetle, Lasioderma serricorne, is quite rare; however, with accumulation of genetic references, such cases accidental pseudo-parasitism have been increasingly recognized. Here, we describe a case asymptomatic gastrointestinal passage L. serricorne in 4-year-old male. Larval identification was conducted PCR-sequencing targeting cytochrome c oxidase subunit 1 using DNA extracted...
: We developed a multistage
Abstract A 75‐year‐old man presented with a 1‐cm large elastic soft subcutaneous nodule on the left side of umbilicus, which when excised showed presence helminthic form within granulomatous lesions. Morphologically, helminth was considered to be genus Dirofilaria , and patient increased serum antibody titer against canine filaria. The partial DNA sequence mitochondrial 12S rRNA gene locus this clinical isolate highest nucleotide identity (89.6%) repens ; however, phylogenetic analysis...
Entamoeba histolytica infections, which can be asymptomatic, are endemic to developing countries; traveling such countries is a risk factor for contracting these infections. A 65-year-old Japanese man was hospitalized coronavirus disease 2019 (COVID-19)-associated respiratory distress, and treated with remdesivir, dexamethasone, oxygen supplementation. Although his condition improved the support discontinued, he developed fever, severe abdominal pain, diarrhea on day 13 of hospitalization....
In developing tropical areas, a wide range of intestinal protozoan parasites inhabit the human gut. However, molecular epidemiologic studies on have generally focused pathogenic species, and meta-genomic approaches in research, including non-pathogenic commensals, are rarely applied. To establish more comprehensive analysis protozoans, we designed polymerase chain reaction (PCR)-sequencing screening methods for Entamoeba spp., commensal Giardia intestinalis, performed such using 174 stool...
Previously we reported that HIV infection is not a risk factor for Entamoeba species but Giardia intestinalis assemblage B in children living Western Kenya. This study aimed to investigate the prevalence of and factors spp. G. Nairobi, cross-sectional included 87 with [HIV(+)] 85 without [HIV(–)]. Stool blood samples were collected detection parasites by PCR immunological analyses using flow cytometry. Socio-behavioral hygienic data questionnaires analyzed statistically. was significantly...