A5065613315- Circular RNAs in diseases
- Inflammasome and immune disorders
- Advancements in PLL and VCO Technologies
- CCD and CMOS Imaging Sensors
- Reconstructive Surgery and Microvascular Techniques
- Analog and Mixed-Signal Circuit Design
- Cancer Mechanisms and Therapy
- Reconstructive Facial Surgery Techniques
- MicroRNA in disease regulation
- RNA and protein synthesis mechanisms
- Cardiovascular Function and Risk Factors
- Autophagy in Disease and Therapy
- Hepatocellular Carcinoma Treatment and Prognosis
- RNA Research and Splicing
- Biomarkers in Disease Mechanisms
- Multimodal Machine Learning Applications
- Pancreatic and Hepatic Oncology Research
- Liver physiology and pathology
- Galectins and Cancer Biology
- Fiscal Policy and Economic Growth
- Human Pose and Action Recognition
- Tracheal and airway disorders
- Embedded Systems Design Techniques
- Vehicle License Plate Recognition
- Handwritten Text Recognition Techniques
Harbin Medical University
2018-2024
Zhuhai People's Hospital
2023-2024
Jinan University
2023-2024
Heilongjiang Academy of Sciences
2021-2024
University of Chinese Academy of Sciences
2022-2023
Southeast University
2022-2023
Beijing Academy of Artificial Intelligence
2022
Shandong Institute of Automation
2022
Chinese Academy of Sciences
2022
Institute of Automation
2022
Metformin is a widely used antidiabetic drug for type 2 diabetes that can play cardioprotective role through multiple pathways.It recognized agonist of AMP-activated protein kinase (AMPK) blocks mitochondrial complex I.The NLRP3 inflammasome has been demonstrated to be activated in diabetic cardiomyopathy (DCM).However, the metformin regulating signaling pathway DCM remains unclear.It reported AMPK inhibit by activating autophagy.The aim this study was investigate whether AMPK/mTOR DCM.In...
Diabetic cardiomyopathy (DCM) is a vital cause of fatalities in diabetic patients. The programmed death cardiomyocytes and inflammation critically contribute to cardiac hypertrophy fibrosis DCM. Furthermore, circular RNA (circRNA) key regulator various diseases. However, the role circRNAs DCM remains be elucidated. Our previous study found that pyroptosis was markedly activated subjected high-glucose conditions, miR-214-3p regulated expression caspase-1. aim this elucidate whether circRNA...
Diabetic cardiomyopathy (DCM) is one of the major causes death in diabetic patients. Its pathogenesis involves inflammation and fibrosis that damages heart tissue impairs cardiac function. Interleukin (IL)-17, a pro-inflammatory cytokine plays an important role variety chronic inflammatory processes can serve as attractive therapeutic target. Anthocyanin, water-soluble natural pigment, possesses impressive anti-inflammatory activity. However, its DCM unclear. Hence, we investigated...
Pancreatic cancer-associated diabetes (PCDM) is a paraneoplastic phenomenon accounting for 1% of new-onset diabetes. We aimed to identify the mediators PCDM and evaluate their usefulness in distinguishing from type 2 diabetes.Secreted proteins MIA PaCa-2 cells were identified by proteomics, those with ≥10-fold overexpression transcriptome analysis assessed bioinformatics glucose uptake assay candidate factors. Expression factors was compared between tumors without immunohistochemistry. Serum...
The incidence of primary liver cancer (PLC) has experienced a significant global increase, primarily attributed to the rise in hepatocellular carcinoma (HCC). Unfortunately, HCC is often diagnosed advanced stages, leaving patients with limited treatment options. Therefore, transformation therapy crucial approach for long-term survival and radical resection HCC. Conversion demonstrated promise When integrated FOLFOX regimen, hepatic artery infusion chemotherapy (HAIC) can significantly...
Myocardial infarction (MI) is a myocardial injury caused by coronary thrombosis or persistent ischemia and hypoxia. Due to its high morbidity mortality, safer more effective treatment strategy urgently needed. Daming capsule (DMC), hypolipidemic drug, reportedly exerts cardioprotective effects in clinical basic research, although protective mechanism remains unknown. To investigate the underlying DMC-mediated improvement of cardiac function post-MI, C57/BL6 mice subjected artery ligation...
Stroke extraction of Chinese characters plays an important role in the field character recognition and generation. The most existing stroke methods focus on image morphological features. These usually lead to errors cross strokes matching due rarely using semantics prior information. In this paper, we propose a deep learning-based method that takes semantic features information into consideration. This consists three parts: registration-based registration establishes rough reference target...
Quality of life and functional improvement have emerged as important goals for patients with oncologic disease. For head neck cancer, free anterolateral thigh (ALT) flaps serve reliable reconstruction provide restoration. Nevertheless, factors affecting the resumption oral feeding are rarely described. This study aimed to evaluate compare outcomes different defect patterns reconstructive ALT flap designs.We retrospectively reviewed cancer undergoing ablation between January 2016 April 2018...
Text-video retrieval focuses on two aspects: cross-modality interaction and video-language encoding. Currently, the mainstream approach is to train a joint embedding space for multimodal interactions. However, there are structural semantic differences between text video, making this challenging fine-grained understanding. In order solve this, we propose an end-to-end graph-based hierarchical aggregation network text-video according hierarchy possessed by video. We design token-level weighted...
Abstract Background Tristetraprolin (TTP) family proteins contain conserved tandem CCCH zinc-finger binding to AU-rich elements and C-terminal NOT1-binding domain. TTP is phosphorylated extensively in cells, its mRNA destabilization activity regulated by protein phosphorylation. Methods We generated an antibody against phospho-Serine316 located at the site examined phosphorylation LPS-stimulated RAW264.7 cells. Knockout of was created cells using CRISPR/Cas9 gene editing explore functions....
Superficial inferior epigastric artery (SIEA) flaps represent a useful option in autologous breast reconstruction. However, the short-fixed pedicle can limit flap inset options. We present challenging successfully addressed by de-epithelialization, turnover, and counterintuitive rotation. A 47-year-old woman underwent left tertiary reconstruction with stacked free using right deep perforator SIEA vessels. Antegrade retrograde anastomoses to internal mammary (IM) vessels were preferred;...
The contemporary financial industry is a highly information-based industry. digital system can establish complete information around various attributes and behaviors of bank accounts. In the core business system, most this constantly changing recorded in real time. Therefore, we achieve goal monitoring money laundering risk account by analyzing relevant element data specific characteristics account. assessment customer classification indicator for accounts composed four basic elements:...
This research aims at studying the operating efficiency of senior citizen welfare institutions in Taiwan. We evaluate technical (TE), technology gap ratio (TGR), and meta-frontier (MTE) by bounded-variable data envelopment analysis. In empirical study, we examine 91 institutes for citizens also apply Tobit regression to study influences relevant factors on efficiency.
This article presents a 12-bit 625 MS/s time-interleaved ADC analog-to-digital converter (ADC) that achieves an SFDR/SNDR of 64.47/59.08 dB near Nyquist rate. An input buffer with replica capacitor is employed to effectively drive the sampling high linearity. A bootstrapped switch operating at adopted eliminate timing mismatch and achieve Also, pipelined utilized as sub-ADC owing its balance rate revolution. The implemented in 45 nm CMOS technology 376 mW power consumption total layout area...
Superficial inferior epigastric artery (SIEA) flaps represent a useful option in autologous breast reconstruction. However, the short-fixed pedicle can limit flap inset options. We present challenging successfully addressed by de-epithelialization, turnover, and counterintuitive rotation. A 47-year-old woman underwent left tertiary reconstruction with stacked free using right deep perforator SIEA vessels. Antegrade retrograde anastomoses to internal mammary (IM) vessels were preferred;...