A5052319319- Food Allergy and Anaphylaxis Research
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Congenital Heart Disease Studies
- Allergic Rhinitis and Sensitization
- Mechanical Circulatory Support Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Economic and Financial Impacts of Cancer
- Central Venous Catheters and Hemodialysis
- Liver Disease and Transplantation
- Diabetes and associated disorders
- Sepsis Diagnosis and Treatment
- Trauma and Emergency Care Studies
- Eosinophilic Esophagitis
- Hemoglobinopathies and Related Disorders
- Clinical Reasoning and Diagnostic Skills
- Lymphoma Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Infective Endocarditis Diagnosis and Management
- Renal Transplantation Outcomes and Treatments
- Disaster Response and Management
- Pulmonary Hypertension Research and Treatments
- Contact Dermatitis and Allergies
- Liver Disease Diagnosis and Treatment
- Diabetes Management and Research
Houston Institute for Clinical Research
2016-2025
Baylor College of Medicine
2016-2025
Texas Children's Hospital
2016-2022
LIM College
2018
Children's National
2017
The University of Texas MD Anderson Cancer Center
2016
Bristol-Myers Squibb (Germany)
2016
University of Washington
2014-2015
Université Grenoble Alpes
2014
Centre Hospitalier Universitaire de Grenoble
2014
Guidelines for cardiopulmonary resuscitation recommend a chest compression rate of at least 100 compressions per minute. Animal and human studies have reported that blood flow is greatest with rates near 120/min, but few used during out-of-hospital (OOH) or the relationship between outcome. The purpose this study was to describe by emergency medical services providers resuscitate patients OOH cardiac arrest determine
Guidelines for cardiopulmonary resuscitation recommend a chest compression rate of at least 100 compressions/min. A recent clinical study reported optimal return spontaneous circulation with rates between and 120/min during out-of-hospital cardiac arrest. However, the relationship survival is still undetermined.Prospective, observational study.Data from Resuscitation Outcomes Consortium Prehospital IMpedance threshold device Early versus Delayed analysis trial.Adults arrest treated by...
Compared with photon radiation (XRT), proton beam therapy (PBRT) reduces dose to normal tissues, which may lead better neurocognitive outcomes. We compared change in intelligence quotient (IQ) over time pediatric patients brain tumors treated PBRT versus XRT.IQ scores were available for 150 (60 had received XRT, 90 PBRT). Linear mixed models examined IQ since (RT) by RT group, controlling demographic/clinical characteristics. Craniospinal and focal subgroups also examined.In the no was...
Up to 10% of cystic fibrosis (CF) children develop cirrhosis by the first decade. We evaluated utility two simple biomarkers, aspartate aminotransferase platelet ratio index (APRI) and FIB-4, in predicting degree pediatric CF liver disease (CFLD) validated biopsy. In this retrospective, cross-sectional study, 67 with CFLD had dual-pass biopsies 104 age- sex-matched without (CFnoLD) serum calculate APRI FIB-4 collected at enrollment. was defined as having following: (1)...
<h3>Objective</h3> To investigate the association of neonatal hypoglycaemia and hyperglycaemia with outcomes in infants hypoxic ischaemic encephalopathy (HIE). <h3>Design</h3> Post hoc analysis CoolCap Study. <h3>Setting</h3> 25 perinatal centres UK, USA New Zealand during 1999–2002. <h3>Patients</h3> 234 at ≥36 weeks’ gestation moderate-to-severe HIE enrolled 214 (91%) had documented plasma glucose follow-up outcome data. <h3>Intervention</h3> Infants were randomised to head cooling for 72...
Venous thromboembolism (VTE), especially pulmonary embolism (PE) and lower extremity deep vein thrombosis (LE-DVT), is a serious potentially preventable complication for patients with cancer undergoing systemic therapy.
Anaphylaxis is a rapid-onset, multisystem, and potentially fatal hypersensitivity reaction with varied reports of prevalence, incidence, mortality. There are limited cases reported severe and/or pediatric anaphylaxis.
The purpose of this study was to prospectively investigate the agreement between epileptogenic zone(s) (EZ) localization by resting-state functional magnetic resonance imaging (rs-fMRI) and seizure onset (SOZ) identified intracranial electroencephalogram (ic-EEG) using novel differentiating ranking criteria rs-fMRI abnormal independent components (ICs) in a large consecutive heterogeneous pediatric intractable epilepsy population without an priori alternate modality informing EZ or prior...
BACKGROUND: There is ongoing controversy about the relative effectiveness of air medical versus ground transportation for severely injured patients. In some systems, crews may provide a higher level care but require longer transport times. We sought to evaluate impact mode on outcome based analysis data from two randomized trials prehospital hypertonic resuscitation. METHODS: Injured patients were enrolled evidence hypovolemic shock (systolic blood pressure ≤70 mm Hg or systolic = 71–90 with...
To investigate the relationship between trauma center volume and outcome.
Although previous single-center studies report the rate of anaphylaxis for oral food challenges (OFCs) as 9% to 11%, little is known regarding epidemiology clinical OFCs across multiple centers in United States.To examine epidemiology, symptoms, and treatment low-risk nonresearch setting.Data were obtained from 2008 2013 through a physician survey 5 allergy geographically distributed States. Allergic reaction rates association with year, hospital, demographics determined using linear mixed...
Rheumatic heart disease (RHD) is the largest cardiac cause of morbidity and mortality in world's youth. Early detection RHD through echocardiographic screening asymptomatic children may identify an early stage disease, when secondary prophylaxis has greatest chance stopping progression. Latent signifies evidence with no known history acute rheumatic fever clinical symptoms.Determine prevalence latent among ages 5-16 Lilongwe, Malawi.This a cross-sectional study which 5 16 were screened for...
To evaluate changes in population characteristics and outcomes a large single-center pediatric patient cohort treated with continuous renal replacement therapy (CRRT) over 10 year course, coincident multiple institutional practice CRRT delivery.A retrospective study comparative analysis of all patients from 2004 to 2013 the neonatal, pediatric, cardiovascular intensive care units within free-standing tertiary hospital.Three hundred eleven total were identified, 38 whom received concurrent...
The number of children receiving extracorporeal membrane oxygenation (ECMO) has increased substantially, and includes a growing population with complex underlying conditions who previously may not have been considered ECMO candidates. However, it remains unclear to what extent the disease impacts risk death in these patients, particularly related malignancy, bone marrow transplantation, congenital heart (CHD), or chromosomal abnormalities. A retrospective study was performed using Pediatric...
Almost 6 million children suffer from food allergies with roughly 2 affected per classroom. Deficiencies in knowledge and discrepancies attitudes within school staff when addressing are associated barriers to care. In this study, teacher knowledge, beliefs, were measured before after a allergy educational session.Three hundred seventy-five personnel of similar age, socioeconomic status, ethnicity, level completed the Chicago Food Allergy Research survey 1-hour session private schools Houston...
Research on venous thromboembolism (VTE) that relies only the International Classification of Diseases (ICD) can misclassify outcomes. Our study aims to discover and validate an improved VTE computable phenotype for people with cancer.We used a cancer registry electronic health record (EHR)-linked longitudinal database. We derived three algorithms were ICD/medication based, natural language processing (NLP) or all combined. then randomly sampled 400 patients from codes (n = 1111) those...
Abstract The epidemiology of cancer‐associated thrombosis (CAT) among uninsured and vulnerable populations in the US is not well‐characterized. We performed a retrospective cohort study for patients with newly diagnosed cancer from 2011 to 2020 at Harris Health System, which cares residents Houston metropolitan area. Patient demographics, NCI comorbidity index, area deprivation index (ADI), histology, staging, systemic therapy data were extracted. CAT included overall venous thromboembolism...