A5105976815- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Hemoglobinopathies and Related Disorders
- Blood Coagulation and Thrombosis Mechanisms
- Cardiovascular Health and Risk Factors
- Acute Ischemic Stroke Management
- Blood Pressure and Hypertension Studies
- Iron Metabolism and Disorders
- Acute Myocardial Infarction Research
- Blood groups and transfusion
- Central Venous Catheters and Hemodialysis
- Acute Myeloid Leukemia Research
- Adipokines, Inflammation, and Metabolic Diseases
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Nutritional Studies and Diet
- Lipoproteins and Cardiovascular Health
- Atherosclerosis and Cardiovascular Diseases
- Folate and B Vitamins Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Genetic Associations and Epidemiology
- Renal Diseases and Glomerulopathies
- Health, Environment, Cognitive Aging
- Erythropoietin and Anemia Treatment
- Cardiovascular Disease and Adiposity
- Diabetes, Cardiovascular Risks, and Lipoproteins
University of Vermont
2016-2025
University of Vermont Medical Center
2016-2025
Harvard University
2024
Massachusetts General Hospital
2024
Wake Forest University
2010-2024
University of Alabama at Birmingham
2010-2023
Palmetto Hematology Oncology
2020-2021
University of Colorado Anschutz Medical Campus
2021
Drexel University
2019
University of Cincinnati Medical Center
2019
Venous thromboembolism (VTE) is the third most common vascular disease. Medical inpatients, long-term care residents, persons with minor injuries, and long-distance travelers are at increased risk.
Background— Poor lifestyle behaviors, including suboptimal diet, physical inactivity, and tobacco use, are leading causes of preventable diseases globally. Although even modest population shifts in risk substantially alter health outcomes, the optimal population-level approaches to improve not well established. Methods Results— For this American Heart Association scientific statement, writing group systematically reviewed graded current evidence for effective dietary habits, increase...
Anemia is viewed as a negative prognostic factor in the elderly population; its independent impact on survival unclear.Baseline hemoglobin quintiles and anemia, defined by World Health Organization criteria, were assessed relation to mortality Cardiovascular Study, prospective cohort study with 11.2 years of follow-up 5888 community-dwelling men women 65 or older, enrolled 1989-1990 1992-1993 4 US communities.A total 1205 participants lowest quintile (<13.7 g/dL for men; <12.6 women), 498...
Myocardial infarction (MI) is an established risk factor for atrial fibrillation (AF). However, the extent to which AF a MI has not been investigated.To examine of incident associated with AF.A prospective cohort 23,928 participants residing in continental United States and without coronary heart disease at baseline were enrolled from Reasons Geographic Racial Differences Stroke (REGARDS) between 2003 2007, follow-up through December 2009.Expert-adjudicated total events (fatal nonfatal).Over...
Background and Purpose— Warfarin reduces stroke risk by approximately 60% in patients with atrial fibrillation (AF). Differences awareness treatment of AF may contribute to racial geographic disparities mortality. The objective was examine predictors the diagnosis warfarin. Methods— RE asons for G eographic a nd R acial D ifferences S troke (REGARDS) is national, population-based, longitudinal study 30 239 blacks whites ≥45 years old oversampling from southeastern belt states. Participants...
Background— Blacks are thought to have a higher risk of venous thromboembolism (VTE) than whites. However, prior studies limited administrative databases that lack specific information on VTE factors or geographic scope. Methods and Results— We ascertained from 3 prospective studies: the Atherosclerosis Risk in Communities Study (ARIC), Cardiovascular Health (CHS), Reasons for Geographic Racial Differences Stroke study (REGARDS). tested association race with using Cox proportional hazard...
Abstract Background: Although venous thromboembolism (VTE) is a significant complication for patients with multiple myeloma (MM) receiving immunomodulatory drugs (IMiDs), no validated clinical model predicts VTE in this population. This study aimed to derive and validate new risk assessment (RAM) IMiD-associated VTE. Methods: Patients newly diagnosed MM IMiDs were selected from the SEER-Medicare database (n=2,397) RAM then data Veterans Health Administration (n=1,251) used externally model....
Background and Purpose— Improved identification of those at risk stroke might improve prevention. We evaluated the association cardiac function biomarker N-terminal pro–B-type natriuretic peptide (NT-proBNP) with in 30 239 black white participants Reasons for Geographic Racial Differences Stroke (REGARDS) cohort. Methods— During 5.4 years follow-up after enrollment 2003 to 2007, NT-proBNP was measured baseline blood samples 546 subjects incident ischemic 956 without stroke. Results— higher...
Testosterone therapy is increasingly prescribed in patients without a diagnosis of hypogonadism. This may be associated with increased risk venous thromboembolism (VTE) through several mechanisms, including elevated hematocrit levels, which increase blood viscosity.
<h3>Objective</h3> We studied circulating interleukin (IL)–6, IL-8, and IL-10 concentrations incident ischemic stroke risk in a biracial cohort, determined if these cytokines mediated the racial disparity incidence affecting black population. <h3>Methods</h3> The Reasons for Geographic Racial Differences Stroke study enrolled 30,237 white men women age ≥45 2003-2007. measured baseline IL-6, case–cohort of 557 participants with over 5.4 years 951 cohort sample. <h3>Results</h3> but not IL-8...
Venous thromboembolism (VTE), especially pulmonary embolism (PE) and lower extremity deep vein thrombosis (LE-DVT), is a serious potentially preventable complication for patients with cancer undergoing systemic therapy.