A5048971163- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Long-Term Effects of COVID-19
- Tuberculosis Research and Epidemiology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- SARS-CoV-2 and COVID-19 Research
- Cardiovascular Function and Risk Factors
- Adipokines, Inflammation, and Metabolic Diseases
- Infective Endocarditis Diagnosis and Management
- Pneumonia and Respiratory Infections
- Inhalation and Respiratory Drug Delivery
- Medical Imaging and Pathology Studies
- Diagnosis and treatment of tuberculosis
- Venous Thromboembolism Diagnosis and Management
- Respiratory and Cough-Related Research
- Medical and Biological Ozone Research
- Pharmacological Effects and Toxicity Studies
- Vascular Malformations and Hemangiomas
- Social Media in Health Education
- Coronary Interventions and Diagnostics
- COVID-19 and healthcare impacts
- Inflammatory Biomarkers in Disease Prognosis
- Cardiac Valve Diseases and Treatments
- Pediatric health and respiratory diseases
- Drug-Induced Hepatotoxicity and Protection
Grigore T. Popa University of Medicine and Pharmacy
2016-2025
Clinica de Pneumologie Iaşi
2012-2025
Spitalul Clinic C.F. Iasi
2023
Institut des Sciences et Technologies Moléculaires d'Angers
2020
Université d'Angers
2020
Universitatea Națională de Știință și Tehnologie Politehnica București
2020
Romanian Academy
2020
Donghua University
2020
Laboratoire de Chimie
2020
National Institute of Research and Development for Biological Sciences
1998
Long COVID is a recently described entity that responsible for significant morbidity and has consequences ranging from mild to life-threatening. The underlying mechanisms are not completely understood, treatment options currently limited, as existing data focus more on risk factors predictors. Smoking been reported factor poor outcomes of acute SARS-CoV-2 infection seems also play role in mediating post-COVID-19 symptoms. We aimed review relevant work addressing the interaction between...
Since epidemiological arguments favouring self-isolation during the COVID-19 pandemic are widely recommended, consequences of social isolation/loneliness older people considered to be at higher risk for severe illness neglected. We identified and described medical, social, psychological, religious issues, indirectly generated by lockdown. Mortality induced SARS-CoV-2 death from other “neglected” issues were put in balance. Arguments strict lockdown most European countries compared with a...
Abstract Background The threat of contagious infectious diseases is constantly evolving, as demographic explosion, travel globalization and changes in human lifestyle increase the risk spreading pathogens, leading to accelerated disease landscape. Of particular interest aftermath superimposing viral epidemics (especially SARS-CoV-2) over long-standing diseases, such tuberculosis (TB), which remains a significant for public health worldwide especially emerging economies. Methods Results...
Pulmonary hamartomas (PHs) are the most common benign lung tumors. Usually, they asymptomatic and incidentally discovered during assessment for other diseases or autopsy exam. In this context, we have performed a retrospective analysis of surgical resections in 5-year series patients diagnosed with PHs Clinic Diseases, Iaşi, Romania, aiming to evaluate their clinicopathological features. A total 27 PH (40.74% males 59.26% females) were evaluated. 33.33% asymptomatic, while others exhibited...
Background: Obstructive sleep apnea (OSA) is increasingly recognized as a chronic condition associated with systemic low-grade inflammation. Elevated levels of inflammatory markers such C-reactive protein (CRP), fibrinogen, TNF-α, and IL-6 have been observed in OSA patients, independent obesity. Tobacco use, known pro-inflammatory factor, may further exacerbate this burden. This study aimed to evaluate whether smoking influences severity newly diagnosed patients. Methods: We conducted...
The SARS-COV-2 pandemic is a worldwide public health problem due to the large medical burden and limited number of therapies available. Corticosteroids have rather unclear efficacy in viral non-SARS-COV-2 pneumonias therefore their use not universally recommended. In pneumonia however, it expected that they can reduce deleterious consequences virus-related systemic inflammation.
Background and Objectives: Atherosclerosis is a multifactorial process in which inflammatory markers have both therapeutic prognostic roles. Recent studies bring into question the importance of assessing new relation to severity peripheral artery disease (PAD), such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR) lymphocyte-to-C-reactive protein (LCR). Materials Methods: We conducted retrospective descriptive study including 652 patients with PAD, who were divided two...
Abstract In the current context of COVID-19 pandemic, a rapid and accessible screening tool based on image processing chest X-rays (CXRs) using machine learning (ML) approaches would be much needed. Initially, we intended to create validate an ML software solution able discriminate basis CXR between SARS-CoV-2-induced bronchopneumonia other etiologies. A systematic search PubMed, Scopus arXiv databases following terms [“artificial intelligence” OR “deep learning” “neural networks”], AND...
Background and Objectives: In the early period after liver transplantation, patients are exposed to a high rate of complications several scores currently available predict adverse postoperative outcomes. However, an ideal, universally accepted validated score events in transplant recipients with hepatitis C is lacking. Therefore, we aimed establish validate machine learning (ML) model short-term outcomes who underwent transplantation. Materials Methods: We conducted retrospective...
Background: The purpuse was to investigate the influence induced by magnesium chloride (MgCl2) and zinc gluconate (ZnG) supplementation on liver kidney injuries experimentally-induced with acetaminophen (AAPh) potentiated ciprofloxacin addition in rats. Material methods: experiment performed 5 animals groups: group 1 – control, treated for 6 weeks normal saline, 1mL/kg; 2 AAPh, 100 mg/ kg/day; 3 AAPh+C, AAPh mg/kg/ day ciprofloxacin, 50mg /kg/day, only last 14 days of experiment; 4...