- Cardiac Health and Mental Health
- Cardiovascular and exercise physiology
- Cardiovascular Health and Disease Prevention
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Lipoproteins and Cardiovascular Health
- Liver Disease Diagnosis and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Disease and Adiposity
- Cardiac Imaging and Diagnostics
- Heart Rate Variability and Autonomic Control
- Obstructive Sleep Apnea Research
- Peripheral Artery Disease Management
- Adipokines, Inflammation, and Metabolic Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Hepatitis C virus research
- Cardiac Valve Diseases and Treatments
- Cardiovascular Effects of Exercise
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Neuroscience of respiration and sleep
- Alcohol Consumption and Health Effects
- Biomarkers in Disease Mechanisms
- Inflammatory Biomarkers in Disease Prognosis
Grigore T. Popa University of Medicine and Pharmacy
2016-2025
Clinical Emergency Hospital Bucharest
2001-2025
Academy of Romanian Scientists
2023-2025
Romanian Academy
2023-2025
Spitalul Clinic C.F. Iasi
2024
Clinica de Pneumologie Iaşi
2020-2023
Spitalul Clinic de Recuperare
1997-2019
Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi
2019
Faculty (United Kingdom)
2013
Objectives: To estimate the trend in arterial hypertension's prevalence, awareness, treatment, and control Romania, starting from latest national survey Study for Evaluation of Prevalence Hypertension Cardiovascular Risk Romania III that has a crucial importance development prevention strategies at level. Methods: A representative sample 1970 Romanian adults (mean age 48.38 years, range 18–80 52.5% women, 72.58% response rate), was enrolled. During two study visits, three blood pressure (BP)...
To present the current epidemiologic situation regarding hypertension's prevalence and control in Romania's adult population (revealed by SEPHAR II survey results) to evaluate their tendency during last 7 years (by comparing with I results).The two cross-sectional national surveys were conducted on a representative sample for Romanian (SEPHAR I: 2017 individuals aged 18-85 years, 45% response rate, II: 1975 18-80 69% rate), means of questionnaire interview, blood pressure (BP) anthropometric...
Left ventricular hypertrophy (LVH) is an important end point of dialysis-associated cardiovascular disease. The objective this study was to evaluate the effect different pediatric reference systems on estimated prevalence LVH in children chronic peritoneal dialysis (CPD).Echocardiographic studies 507 CPD patients from neonatal age 19 years were collected 55 units around globe. We compared basis traditional cutoff left mass (LVM) index (>38.5 g/m(2.7)) with three novel definitions that...
Atherosclerosis is the basis of cardiovascular continuum in peripheral artery disease (PAD) patients. Limiting functional decline and increasing quality life are main objectives for these We conducted a prospective cohort study on 101 patients with PAD admitted to single center Northeast Romania. used an index score evaluate 10-year mortality risk assessment based scores we divided into two groups: low low-intermediate group (49 cases, 48.5%) high-intermediate high-risk (52 51.5%). analyzed...
Background and Objectives: Functional capacity (FC) assessed via cardiopulmonary exercise testing (CPET) is a novel, independent prognostic marker for patients with coronary artery disease (CAD). Neutrophil to lymphocyte ratio (NLR) platelet (PLR) are two readily available predictors of systemic inflammation cardiovascular event risk, which could be used as cost-effective poor FC. The purpose this study was evaluate the utility NLR PLR in predicting FC CAD recent elective percutaneous...
Background: The subendocardial viability ratio (SEVR), also known as the Buckberg index, is a parameter of arterial stiffness with indirect prognostic value in assessing long-term cardiovascular risk. Materials and Methods: We conducted prospective cohort study on 70 patients uncomplicated hypertension admitted to county medical reference hospital. analyzed demographics, laboratory data, parameters risk scores (SCORE Framingham scores) aimed identify paraclinical associated increased...
Abstract Background Cardiac rehabilitation (CR) plays an important role in heart failure (HF) contributing to stopping functional decline, relieving symptoms and increasing quality of life combination with optimal therapeutic management. Purpose We aimed evaluate the impact participating a CR program after 6 months terms biological (N-terminal pro b-type natriuretic peptide [NT-proBNP], inflammatory biomarkers) echocardiographic parameters (left right ventricle global longitudinal [LV, RV...
Abstract Background Sudden cardiac death (SCD) is a rare but tragic event which can involve young and apparently healthy individuals. Several heart conditions, such as hypertrophic cardiomyopathy (HCM), the most frequent cause of SCD in adults, may not be diagnosed early needed. Therefore, proper screening methods protocols are required for athletes individuals who engage chronic intense physical activity. Purpose Current guidelines recommend high-intensity activities based on patient...
Abstract Background Cardiac rehabilitation (CR) in patients with heart failure (HF) and chronic coronary syndromes (CCS), contributes to the improvement of symptoms, biological parameters (lipids, blood glucose, inflammatory status, NT-proBNP) echocardiographic (systolic diastolic function, tissue Doppler parameters, myocardial strain analysis left right ventricle atrial function assessment by strain) prognostic value increasing exercise capacity improving quality life. Purpose We aimed...
The current cardiovascular disease (CVD) primary prevention guidelines prioritize risk stratification by using clinical scores. However, subclinical atherosclerosis may rest long term undetected. This study aimed to evaluate multiple parameters in relation several CV scores asymptomatic individuals. A cross-sectional, single-center included 120 CVD subjects. Four were computed: SCORE, Framingham, QRISK, and PROCAM. Subclinical has been determined carotid intima-media thickness (cIMT), pulse...
Background and Objectives: Atherosclerosis is a multifactorial process in which inflammatory markers have both therapeutic prognostic roles. Recent studies bring into question the importance of assessing new relation to severity peripheral artery disease (PAD), such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR) lymphocyte-to-C-reactive protein (LCR). Materials Methods: We conducted retrospective descriptive study including 652 patients with PAD, who were divided two...
Chronic inflammation plays an essential role in the pathophysiology of both arterial hypertension (HTN) and coronary artery disease (CAD), is more pronounced individuals with a non-dipper circadian blood pressure (BP) pattern. A non-dipping BP pattern turn associated increased cardiovascular morbi-mortality, higher risk atherosclerotic events. Neutrophil to lymphocyte ratio (NLR), monocyte (MLR) platelet (PLR) are readily available predictors systemic risk. The purpose our study evaluate...