A5100757660- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Mental Health Research Topics
- Advanced MRI Techniques and Applications
- Migraine and Headache Studies
- COVID-19 Clinical Research Studies
- Epigenetics and DNA Methylation
- Neurological Disease Mechanisms and Treatments
- Diet and metabolism studies
- Long-Term Effects of COVID-19
- Radiomics and Machine Learning in Medical Imaging
- Neurological disorders and treatments
- Stuttering Research and Treatment
- Optical Imaging and Spectroscopy Techniques
- Neurotransmitter Receptor Influence on Behavior
- Neuroinflammation and Neurodegeneration Mechanisms
- Heart Rate Variability and Autonomic Control
- Pancreatic and Hepatic Oncology Research
- Advanced Glycation End Products research
- Circadian rhythm and melatonin
- Bipolar Disorder and Treatment
- Uterine Myomas and Treatments
- Trigeminal Neuralgia and Treatments
- Voice and Speech Disorders
- Autophagy in Disease and Therapy
The Affiliated Yongchuan Hospital of Chongqing Medical University
2013-2025
Chongqing Medical University
2013-2025
Capital Medical University
2023-2025
Beijing Anding Hospital
2023-2025
Hebei Institute of Physical Education
2025
Shanxi University
2024
Yanbian University
2024
Wenzhou Medical University
2024
Affiliated Eye Hospital of Wenzhou Medical College
2024
Chengdu University of Information Technology
2024
Adolescent major depressive disorder (MDD) is associated with serious adverse implications for brain development and higher rates of self-injury suicide, raising concerns about its neurobiological mechanisms in clinical neuroscience. However, most previous studies regarding the alterations adolescent MDD focused on single-modal images or analyzed different modalities separately, ignoring potential role aberrant interactions between structure function psychopathology.
To investigate the clinical and chest CT characteristics of COVID-19 pneumonia explore radiological differences between influenza.A total 122 patients (61 men 61 women, 48 ± 15 years) confirmed with (23 25 47 19 influenza were enrolled in study. Thin-section was performed. The data findings recorded.The most common symptoms fever (74%) cough (63%), 102 (83%) had Wuhan contact. Pneumonia 50 (45%) distributed peripheral regions lung, while it showed mixed distribution 26 (p = 0.022). features...
Background: It has remained a concern whether any long-term pulmonary sequelae exist for COVID-19 survivors. Methods: Forty-one patients (22 men and 19 women, 50 ± 14 years) confirmed with performed follow-up chest CT cardiopulmonary exercise testing at 7 months after discharge. Patients were divided into fibrosis group non-fibrosis according to the evidence of on CT. The clinical data findings recorded analyzed. Results: predominant patterns abnormalities observed discharge parenchymal band...
Major depressive disorder (MDD) in adolescents poses a significant threat to physical health. Previous studies have indicated that with MDD exhibit immune activation. This study aimed compare cytokine levels healthy controls and assess their diagnostic value. cross-sectional included 58 adolescent patients depression from Beijing Anding Hospital (outpatients inpatients) 40 recruited the community. Multiplex analysis (Luminex xMAP) was used measure serum of several cytokines. Data performed...
The clinical benefits of targeting the ventral intermediate nucleus (VIM) for treatment tremors in essential tremor (ET) patients suggest that VIM is a key hub network generation and propagation can be considered as seed region to study network.However, little known about central ET patients.Twentysix 26 matched healthy controls (HCs) were included this study.After considering structural head-motion factors establishing accuracy our region, seedbased functional connectivity (FC) analysis...
We present clinical and chest computed tomography (CT) features of 5 cases pediatric patients with 2019 novel coronavirus. Two had fever dry cough, whereas the rest 3 were asymptomatic. Three unilateral ground glass opacities or without consolidation in subpleural region on high-resolution CT, 1 patient bilateral opacities, was negative for CT. note that up to 66.7% asymptomatic pulmonary lesions, so children Wuhan contact are recommended do a coronavirus real-time fluorescence polymerase...
Background: COVID-19 is a global pandemic. The prevention of SARS-CoV-2 infection and the rehabilitation survivors are currently most urgent tasks. However, after patients with discharged from hospital, how long antibodies persist, whether lung lesions can be completely absorbed, cardiopulmonary abnormalities exist remain unclear. Methods: A total 56 were followed up for 12 months, examinations including serum virus-specific antibodies, chest CT, exercise testing. Results: IgG titer...
ABSTRACT Introduction The heterogeneous clinical features of essential tremor indicate that the dysfunctions this syndrome are not confined to motor networks, but extend nonmotor networks. Currently, these neural network in remain unclear. In study, independent component analysis resting‐state functional MRI was used study mechanisms. Methods Thirty‐five patients and 35 matched healthy controls with neuropsychological tests were included, eight networks identified. After considering...
Childhood trauma is a leading risk factor for adolescents developing major depressive disorder (MDD); however, the underlying neuroimaging mechanisms remain unclear. This study aimed to investigate association among childhood trauma, MDD and brain dysfunctions by combining static dynamic network models. We recruited 46 first-episode drug-naïve adolescent patients with (MDD-CT), 53 without (MDD-nCT), 90 healthy controls (HCs) resting-state functional magnetic resonance imaging (fMRI) scans;...
Abstract Lipid homeostasis is crucial for growth and development of organisms. Several cytochrome P450 monooxygenases (CYPs) are involved in lipid metabolism. The function Cyp311a1 the anterior midgut as a regulator phosphatidylethanolamine (PE) metabolism Drosophila melanogaster has been demonstrated, depletion caused larval arrest that was partially rescued by supplying PE. In this study, we investigated role CYP311A1 wing morphogenesis . Using GAL4‐UAS system, selectively knocked down...
Abstract Background Compared to other healthcare workers, nurses are more vulnerable the potentially devastating effects of pandemic-related stressors. Studies have not yet investigated deeper characteristics relationship between team resilience and performance among during COVID-19 pandemic. This study aimed elucidate networks Methods A cross-sectional involving 118 nursing teams comprising 1627 practice from four tertiary-A secondary-A hospitals in Shandong Province, China, was conducted....
Abstract Background The age-related heterogeneity in major depressive disorder (MDD) has received significant attention. However, the neural mechanisms underlying such still need further investigation. This study aimed to explore common and distinct functional brain abnormalities across different age groups of MDD patients from a large-sample, multicenter analysis. Methods analyzed sample consisted total 1238 individuals including 617 (108 adolescents, 12–17 years old; 411 early-middle...
Near work is generally considered as a risk factor for myopia onset and progression. This study aimed to investigate the choroidal responses brief-period of near in children young adults. Thirty myopic medical students (aged 18-28 years) 30 8-12 participated this study. The submacular total area (TCA), luminal (LA), stromal (SA), vascularity index (CVI) choriocapillaris flow deficit (CcFD), well subfoveal thickness (SFCT) were measured with swept-source optical coherence tomography/optical...
Abstract Background Nowadays, moderate gaming behaviors can be a pleasant and relaxing experiences among adolescents. However, excessive behavior may lead to disorder (GD) that disruption of normal daily life. Understanding the possible risk factors this emerging problem would help suggest effective at preventing intervening. This study aimed investigate prevalence GD analyze its adolescents with GD. Methods Data were collected between October 2020 January 2021. In total, sample 7901...
<title>Abstract</title> Childhood trauma (CT) is a major risk factor for adolescent depressive disorder (MDD), yet its neurobiological underpinnings and longitudinal treatment effects remain poorly characterized. Leveraging graph theory resting-state fMRI in 343 adolescents with MDD (211 CT history [MDD-CT], 106 without [MDD-NCT]) 149 healthy controls, we identified CT-associated functional connectome disruptions marked by increased network randomness topological deficits default mode (DMN)...
Functional connectivity density (FCD) could identify the abnormal intrinsic and spontaneous activity over whole brain, a seed-based resting-state functional (RSFC) further reveal altered network with identified brain regions. This may be an effective assessment strategy for headache research. study is to investigate RSFC architecture changes of in patients medication overuse (MOH) using FCD methods.3D structure images MRI data were obtained from 37 MOH patients, 18 episodic migraine (EM) 32...
Abstract Objective Major depressive disorder (MDD) and bipolar (BD) are serious chronic disabling mental emotional disorders, with symptoms that often manifest atypically in children adolescents, making diagnosis difficult without objective physiological indicators. Therefore, we aimed to objectively identify MDD BD adolescents by exploring their voiceprint features. Methods This study included a total of 150 participants, 50 patients, healthy controls aged between 6 16 years. After...
Major depressive disorder (MDD) and bipolar (BD) share clinical features, which complicates their differentiation in settings. This study proposes an innovative approach that integrates structural connectome analysis with machine learning models to discern individuals MDD from BD. High-resolution MRI images were obtained diagnosed or BD HCs. Structural connectomes constructed represent the complex interplay of brain regions using advanced graph theory techniques. Machine employed unique...