A5087124459- Plant Disease Resistance and Genetics
- Chromosomal and Genetic Variations
- Plant pathogens and resistance mechanisms
- Microbial Community Ecology and Physiology
- Pharmacological Effects of Natural Compounds
- Cardiomyopathy and Myosin Studies
- Bacteriophages and microbial interactions
- Identification and Quantification in Food
- Agronomic Practices and Intercropping Systems
- Muscle Physiology and Disorders
- Animal Disease Management and Epidemiology
- Microbial Metabolic Engineering and Bioproduction
- Signaling Pathways in Disease
- Biochemical effects in animals
- Brucella: diagnosis, epidemiology, treatment
- Plant Virus Research Studies
- Agricultural pest management studies
- Medicinal Plants and Bioactive Compounds
- Genomics and Phylogenetic Studies
National Center for Biotechnology
2018
Abstract The sarcomeric troponin-tropomyosin complex is a critical mediator of excitation-contraction coupling, stability and force generation. We previously reported that induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) from patients with dilated cardiomyopathy (DCM) mutation, troponin T (TnT)-R173W, display sarcomere protein misalignment impaired contractility. Yet it not known how TnT mutation causes dysfunction microdomains these events contribute to proteins in presence...
Molecular markers have become crucial part of genetics due to their use in various branches it, such as positional cloning, which includes identification genes responsible for desired traits and management backcrossing programs, well modern plant breeding, human forensics. Retrotransposons are a major component all eukaryotic genomes, makes them suited molecular markers. The retrotransposons comprise most large genomes among plants; differences prevalence explain the variation genome size....