A5101811397- Fungal Biology and Applications
- Acute Lymphoblastic Leukemia research
- Conducting polymers and applications
- Plant biochemistry and biosynthesis
- Acute Myeloid Leukemia Research
- Mycorrhizal Fungi and Plant Interactions
- Perovskite Materials and Applications
- Horticultural and Viticultural Research
- Vibration Control and Rheological Fluids
- RNA modifications and cancer
- Immune cells in cancer
- Chalcogenide Semiconductor Thin Films
- Phagocytosis and Immune Regulation
- Immunotherapy and Immune Responses
- Yeasts and Rust Fungi Studies
- Photosynthetic Processes and Mechanisms
- Plant Pathogens and Fungal Diseases
- Histone Deacetylase Inhibitors Research
- Plant Stress Responses and Tolerance
- Hematopoietic Stem Cell Transplantation
- Lung Cancer Treatments and Mutations
- Transition Metal Oxide Nanomaterials
- Phytochemical compounds biological activities
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Traditional Chinese Medicine Analysis
Xinxiang Medical University
2023-2024
National Institute of Measurement and Testing Technology
2023-2024
Central South University
2023
Ningbo Product Quality Supervision and Inspection Institute
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2010-2020
Soochow University
2005-2020
Soochow University
2020
Tongji University
2015-2016
Guangdong Polytechnic of Science and Technology
2014
Academy of Medical Sciences
2012
Abstract Cancer phototheranostics utilizing plasmonic materials is attracting considerable interest due to its high spatiotemporal precision and specificity, remote controllability, superior therapeutic efficacy, low systemic side effects. Exploring new with excellent photothermal properties at the frontier of cancer phototheranostics. Herein, this work systematically investigates spiky Au nanoparticles (NPs) different shaped central cores – nanosphere , nanocube nanorod (AuNR). It shown...
Dozens of Traditional Chinese Medicine (TCM) formulas have been used for promotion "blood production" centuries, and we are interested in developing novel thrombopoietic medicines from these TCMs. Our previous studies demonstrated the hematopoietic effects DangGui BuXue Tong (DBT), a formula composed Radix Angelicae Sinensis Astragali animal cellular models. As step further to identify characterize active chemical components DBT, tested particularly, polysaccharide-enriched fractions root...
Ganoderma lucidum is one of the well-known medicinal basidiomycetes worldwide. The mitochondrion, referred to as second genome, an organelle found in most eukaryotic cells and participates critical cellular functions. Elucidating structure function this genome important understand completely genetic contents G. lucidum. In study, we assembled mitochondrial analyzed differential expressions its encoded genes across three developmental stages. a typical circular DNA molecule 60,630 bp with GC...
CD47 and its receptor signal regulatory protein α (SIRPα) act as a dominant antiphagocytic, "don't eat me" signal. Recent studies reveal CD24 novel target for cancer immunotherapy by macrophages in ovarian breast cancer. However, whether simultaneous blockade of bispecific antibody may result potential synergy is still unclear. In the present study, we first time designed developed fusion protein, PPAB001 cotargeting CD24. Data demonstrate that CD47/SIRPα CD24/Siglec-10 signaling potently...
Ganoderma lucidum is a white-rot fungus best-known for its medicinal activities. We have previously sequenced genome and annotated the protein coding genes. However, long non-coding RNAs in G. not been analyzed. In this study, we identified characterized intergenic (lincRNA) systematically. developed computational pipeline, which was used to analyze RNA-Seq data derived from samples collected three developmental stages. A total of 402 lincRNA candidates were identified, with an average...
Tanshinone IIA (Tan IIA) is a diterpene quinone extracted from the root of Salvia miltiorrhiza, Chinese traditional herb. Although previous studies have reported anti-tumor effects Tan on various human cancer cells, underlying mechanisms are not clear. The current study was undertaken to investigate molecular IIA's apoptotic leukemia cells in vitro.The cytotoxicity different types cell lines evaluated by 3-[4,5-dimethylthiazol-2,5]-diphenyl tetrazolium bromide (MTT) assay treated without or...
Abstract Ganoderma lucidum is a white-rot fungus best-known for its medicinal and ligninolytic activities. To discover the underlying genes responsible these activities, we identified characterized natural antisense transcripts (NATs) using strand-specific (ss) RNA-seq data obtained from mycelia, primordia fruiting bodies. NATs were custom pipeline then subjected to functional enrichment differential expression analyses. A total of 1613 cis- 244 trans- sense identified. Mapping GO terms KEGG...
Wolfiporia cocos (F. A. Wolf) has been praised as a food delicacy and medicine for centuries in China. Here, we present the genome transcriptome of Chinese strain CGMCC5.78 W. cocos. High-confidence functional prediction was made 9277 genes among 10,908 total predicted gene models genome. Up to 2838 differentially expressed (DEGs) were identified be related sclerotial development by comparing transcriptomes mycelial tissues. These DEGs are involved mating processes, differentiation fruiting...
Electromagnetic actuated active suspension benefits control and energy harvesting from vibration at the same time. However, rotary type electromagnetic introduces a significant extra mass on unsprung due to inertia of rotating components actuator. The magnitude introduced is studied based gearbox actuator ball screw geometry also influence equivalent significantly. performance simulation or logic derived should take this into account. Besides, an force be compensated nonlinear features...
With the increasing population worldwide, consumption of fossil energy is grows to be enormous [...]
The low-temperature preparation requirement of perovskite solar cells (PSCs) enables the fabrication flexible (f-PSCs). This technique has great potential for commercialization but is still accompanied by challenges in preparing dense and low-defect films on polymer substrates. In this work, propylammonium chloride (PACl) was introduced during process a two-step sequentially deposited film. ammonium halide salt long alkyl chain that can be incorporated into A sites lacking volatile cations...
To investigate whether miRNA-30a is involved in the pathogenesis of ITP by affecting differentiation Th17 cells, and to explore its possible mechanism through verification target gene SOCS3 for prediction miRNA-30a.Firstly, a chronic mouse model was established. The expression RORγt spleen mononuclear cells were detected their correlation analyzed. Secondly, luciferase vector containing 3'UTR green fluorescent miRNA constructed. Luciferase fluorescence detection, real-time quantitative PCR...
This project has developed a 633nm iodine steady frequency laser evaluation system. The overall structure is mainly composed of the national length laser, new shooting monitoring and technical unit, frequent Through design experiments, respectively In three major measurement technology indicators peak difference, stability frequency, duplication experimental result was not certainty wavelength system 2.9 × 10<sup>-11</sup> to meet relevant indicators.