A5100762775- Cancer-related molecular mechanisms research
- DNA Repair Mechanisms
- Signaling Pathways in Disease
- TGF-β signaling in diseases
- RNA modifications and cancer
- DNA and Nucleic Acid Chemistry
- RNA and protein synthesis mechanisms
- Connective Tissue Growth Factor Research
- Endoplasmic Reticulum Stress and Disease
- Cytokine Signaling Pathways and Interactions
- Toxin Mechanisms and Immunotoxins
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
- Medicinal Plant Pharmacodynamics Research
- Immune Response and Inflammation
- Bone and Dental Protein Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Porphyrin Metabolism and Disorders
- Glycosylation and Glycoproteins Research
- Liver Disease Diagnosis and Treatment
- Sirtuins and Resveratrol in Medicine
Gansu Provincial Hospital
2014-2025
Jiangsu University
2020
Yixing People's Hospital
2020
Air Force Medical University
2013
University of Chicago Medical Center
2013
Molecular Oncology (United States)
2013
Xiangya Hospital Central South University
2006
Small RNAs derived from tRNAs are attracting considerable attention; however, the effects of tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs) as biomarkers have not been investigated in early-stage breast cancer (EBC). The study aimed to explore whether tRFs tiRNAs could be detected plasma they serve diagnostic biomarkers. was conducted four phases. Thirty were selected by high-throughput sequencing screening phase then assessed training, testing, external validation phases qRT-PCR....
We aimed to explore the relationship between MBOAT7 rs641738 gene polymorphism and liver fibrosis inflammation. A total of 214 patients with metabolic dysfunction-associated steatotic disease (MASLD) were allocated into mild-to-moderate severe groups based on degree. The genotypes at locus evaluated. Differences in clinical biochemical indicators, as well genotype allele frequency distributions polymorphism, analyzed across varying degrees fibrosis. Additionally, differences among different...
Mesenchymal stem cells (MSCs) are multipotent progenitors that can undergo osteogenic differentiation under proper stimuli. We demonstrated BMP9 is one of the most BMPs. However, molecular mechanism underlying BMP9-initiated signaling in MSCs remains unclear. Through gene expression profiling analysis we identified several candidate mediators signaling. Here, focus on such mediator and investigate functional role cysteine-rich with EGF-like domains 2 (Creld2) Creld2 was originally as an ER...
This study aims to explore the role of ERCC5 genetic polymorphisms in gastric cancer and their relationship with metastasis recurrence cancer.A total 200 patients 133 healthy subjects were enrolled. MassARRAY iPLEX® technology was used genotype rs2016073, rs751402, rs2094258, rs2296147, rs2296148 between control group group. The explored. differences sociodemographic characteristics compared using chi-square test. loci analyzed by test.There no significant difference males females (p=0.628),...