A5018011674- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Mechanical Circulatory Support Devices
- Trauma Management and Diagnosis
- Lung Cancer Treatments and Mutations
- Organ and Tissue Transplantation Research
- Renal Transplantation Outcomes and Treatments
- Pleural and Pulmonary Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Medical Imaging and Pathology Studies
- Respiratory Support and Mechanisms
- Cancer Diagnosis and Treatment
- Myasthenia Gravis and Thymoma
- Spinal Fractures and Fixation Techniques
- Pectus Deformity Diagnosis and Treatment
- Cancer Cells and Metastasis
- Colorectal Cancer Treatments and Studies
- Shoulder and Clavicle Injuries
- Polyomavirus and related diseases
- Cancer Immunotherapy and Biomarkers
- Renal cell carcinoma treatment
Université de Strasbourg
2016-2025
Hôpitaux Universitaires de Strasbourg
2015-2025
Hôpital Jeanne de Flandre
2025
Inserm
2018-2024
Hôpital Civil, Strasbourg
2015-2024
Regenerative NanoMedicine
2016-2024
Unité de recherche sur les maladies cardiovasculaires et métaboliques
2020-2023
Society of Thoracic Surgeons
2017
Valve (United States)
2017
Emory and Henry College
2017
We evaluated KRAS (mKRAS (mutant KRAS)) and BRAF (mBRAF BRAF)) mutations to determine their prognostic potential in assessing patients with colorectal cancer (CRC) for lung metastasectomy.Data were reviewed from 180 a diagnosis of CRC who underwent metastasectomy between January 1998 December 2011.Molecular analysis revealed mKRAS 93 (51.7%), mBRAF 19 (10.6%). In univariate analyses, overall survival (OS) was influenced by thoracic nodal status (median OS: 98 months pN-, 27 pN+, P<0.0001),...
Identifying patients who will experience lung cancer recurrence after surgery remains a challenge. We aimed to evaluate whether mutant forms of epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene homolog (KRAS) (mEGFR mKRAS) are useful biomarkers in resected non-small cell (NSCLC).We retrospectively reviewed data from 841 underwent molecular testing for NSCLC between 2007 2012.mEGFR was observed 103 (12.2%), mKRAS 265 (31.5%). The median overall survival (OS) time...
ABSTRACT Background Pulmonary metastasectomy of renal cell carcinomas (RCC) remains controversial. Thoracic lymph node involvement (LNI) is a known prognostic factor. The aim our analysis to evaluate whether patients with LNI, and particularly N2 patients, should be excluded from surgical treatment. Methods We retrospectively reviewed data 122 who underwent operations at two French thoracic surgery departments between 1993 2011 for RCC lung metastases. Results population consisted 38 women...
Resection of thymic tumours including the removal both tumour and thymus gland (thymothymectomy; TT) is procedure choice recommended in most relevant articles literature. Nevertheless, recent years, some authors have suggested that resection (simple thymomectomy; ST) may suffice from an oncological standpoint patients with early-stage thymoma who do not myasthenia gravis (MG) (non-MG). The goal our study was to compare short- long-term outcomes ST versus TT non-MG thymomas using European...
The management of pIIIA-N2 non-small-cell lung cancer (NSCLC) is still controversial. In particular, there are wide variations in overall survival (OS), suggesting the existence subgroups among N2 patients. We aimed to evaluate prognostic value microscopic pN2 NSCLC.Between 1996 and 2015, data from all 982 pathologically stage IIIA-N2 patients who underwent surgery with curative intent for NSCLC were retrospectively reviewed. Microscopic disease was defined as a nodal metastasis ranging 0.2...
The high mortality rate observed on the regular waiting list (RWL) before lung transplantation (LTx) prompted French organ authorities to set up in 2007 a dedicated graft allocation strategy, so-called 'high-emergency list' (HEWL), for patients with an abrupt worsening of their respiratory function. This study reports early results this new system.Among 11 active LTx programmes, 7 were able provide full outcome data by 31 December 2011. medical records 101 who listed HEWL from July 2011...
This study evaluates the number of video-assisted thoracic surgery-lobectomies (VATS-lobectomies) required for an experienced consultant surgeon to obtain competence and perform standard quality surgery.We have analysed initial VATS-experience (January 2012 September 2014) a confirmed senior who has performed 145 consecutive anatomic resections by thoracoscopy. After excluding bilobectomies, segmentectomies, lobectomies infectious disease, we focused into 119 lobectomies, classified 4...
The diagnosis of ovarian torsion is made with delay among pre-pubertal girls and the management after surgical detorsion poorly codified. We interested in French experience during last two decades. Retrospective study pediatric surgery centers from January 2000 to December 2022 concerning who presented at least 1 episode prepubertal period. Data collected included patient history, symptomatology, biological imaging assessment first episode, emergency surgery, follow-up including recurrence....
Since video-assisted thoracic surgery (VATS) was first performed in the early 1990s, there have been many developments, and conversion rate has decreased over years. This article highlights specific outcomes of patients undergoing to thoracotomy despite initially scheduled VATS lung resection.We retrospectively reviewed 501 who underwent thoracoscopic anatomic resection (i.e. lobectomy, segmentectomy or bilobectomy) between 1 January 2012 August 2017 at our institution. We explored risk...