A5043682073- Mechanical Circulatory Support Devices
- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Fuel Cells and Related Materials
- Renal Transplantation Outcomes and Treatments
- Cardiac pacing and defibrillation studies
- Prosthetics and Rehabilitation Robotics
- Heart Failure Treatment and Management
- Hydrogen's biological and therapeutic effects
- Peripheral Nerve Disorders
- Congenital Heart Disease Studies
- Forensic Toxicology and Drug Analysis
- Organ Donation and Transplantation
- Acute Kidney Injury Research
- Organ and Tissue Transplantation Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Musculoskeletal synovial abnormalities and treatments
- Hemodynamic Monitoring and Therapy
- Orthopedic Surgery and Rehabilitation
- Treatment of Major Depression
- Cardiac electrophysiology and arrhythmias
Harefield Hospital
2016-2025
Guy's and St Thomas' NHS Foundation Trust
2021-2025
Royal Brompton & Harefield NHS Foundation Trust
2016-2024
National Health Service
2024
University Health Network
2021
University of Toronto
2021
Royal Stoke University Hospital
2014
Abstract Left ventricular assist device (LVAD) is now a routine therapy for advanced heart failure. Minimally invasive approach via thoracotomy LVAD implantation getting popular due to its potential advantage over the conventional sternotomy in terms of reduced risk at re‐operation sternal sparing. We compared approaches (thoracotomy and sternotomy) determine superiority. involved fitting inflow cannula into left ventricle apex anterior anastomosis outflow graft ascending aorta right...
Background We evaluated the potential benefits of renin‐angiotensin‐aldosterone system inhibitors (RAASi) in patients with left ventricular assist device support. Methods and Results A total 165 consecutive undergoing implant alive at 6‐month on support were studied. RAASi status after visit along clinical reasons for nonprescription/uptitration retrospectively assessed. The primary outcome was a composite heart failure hospitalization or cardiovascular death between 6 24 months implant....
Ketamine abuse is being increasingly reported worldwide. The drug can produce a dissociative state and hallucinations, making ketamine favorite recreational agent among addicts. Chronic damage many organs, including the brain, heart, liver, gastrointestinal tract, genitourinary system. We report patient with chronic who presented severe cachexia, upper involvement, hepatobiliary dysfunction, acute kidney injury.
Venovenous extracorporeal membrane oxygenation (VV-ECMO) is increasingly being used in acutely deteriorating patients with end-stage lung disease as a bridge to transplantation (BTT). It can allow critically ill recipients remain eligible for transplants (LTx) while reducing pretransplant deconditioning. We analyzed early- and midterm postoperative outcomes of on VV-ECMO BTT the impact preoperative posttransplant survival outcomes.All consecutive LTx performed at our institution between...
Post-cardiotomy cardiogenic shock (PCCS) results in substantial morbidity and mortality, whereas refractory cases require mechanical circulatory support (MCS). The aim of the study was to compare extracorporeal membrane oxygenation (ECMO) ventricular assist devices (VADs) utilized management PCCS.In total, 56 consecutive patients who developed PCCS from 2005 2014 required MCS as a bridge decision-24 were supported with VAD 32 an ECMO. Groups compared respect pre- intraoperative...
Published guidance concerning emergency management of left ventricular assist device (LVAD) recipients is both limited and lacking in consensus which increases the risk delayed and/or inappropriate actions.In our specialist tertiary referral centre we developed, by iteration, a novel in-hospital resuscitation algorithm for LVAD emergencies validated through simulation assessment multi-disciplinary team. A Mechanical Life Support course was established to provide theoretical practical...
Acute kidney injury (AKI) after lung transplantation (LTx) is a common complication. We aimed to assess whether donation circulatory death (DCD) associated with an increased risk of AKI and renal replacement therapy (RRT) in the early postoperative period compared brain (DBD). Retrospective data on cohort (N = 95) LTx patients (DCD n 17, DBD 78) characterized by no use ex-vivo perfusion were analyzed for incidence within 30 days RRT 7 days. After optimal full matching, imbalance remained...
Objectives: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is increasingly being used in acutely deteriorating patients with end-stage lung disease as a bridge to transplantation (BTT). It can allow critically ill recipients remain eligible for transplant (LTx) while reducing pretransplant deconditioning. We analyzed early and mid-term postoperative outcomes of on VV-ECMO BTT the impact preoperative posttransplant survival outcomes. Methods: All consecutive LTx performed at our...
Abstract Although the activated partial thromboplastin time (aPTT) has historically been method of choice for anticoagulation monitoring in patients undergoing mechanical circulatory support with intravenous unfractionated heparin, it is being progressively superseded by anti-factor Xa (anti-Xa) method. A retrospective single-arm, single-centre analysis 20 who underwent total artificial heart implantation entailed simultaneous determinations aPTT and anti-Xa. Agreement between these...