A5046355938- Vestibular and auditory disorders
- Transcranial Magnetic Stimulation Studies
- Migraine and Headache Studies
- Functional Brain Connectivity Studies
- Ophthalmology and Eye Disorders
- Neural dynamics and brain function
- Glaucoma and retinal disorders
- Hearing, Cochlea, Tinnitus, Genetics
- EEG and Brain-Computer Interfaces
- Advanced Neuroimaging Techniques and Applications
- Cerebral Venous Sinus Thrombosis
- Computational Physics and Python Applications
- Hemispheric Asymmetry in Neuroscience
- Visual perception and processing mechanisms
- Methane Hydrates and Related Phenomena
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Peripheral Nerve Disorders
- Psychosomatic Disorders and Their Treatments
- Environmental Monitoring and Data Management
- Traumatic Brain Injury Research
- Mental Health Research Topics
- Spectroscopy and Laser Applications
- Neural and Behavioral Psychology Studies
- Suicide and Self-Harm Studies
- Molecular Spectroscopy and Structure
Laureate Institute for Brain Research
2014-2025
University of Minnesota
2020-2025
University of Tulsa
2016-2025
University of Oklahoma
2025
Oklahoma State University Center for Health Sciences
2025
Mercy Research
2025
University of Minnesota System
2023-2024
Minnesota Gastroenterology
2023
National Hospital for Neurology and Neurosurgery
2022
University College London
2022
We present diagnostic criteria for motion sickness, visually induced sickness (VIMS), disorder (MSD), and VIMS (VIMSD) to be included in the International Classification of Vestibular Disorders. Motion are normal physiological responses that can elicited almost all people, but susceptibility severity high enough response considered a some cases. This report provides guidelines evaluating signs symptoms caused by physical or visual diagnosing an individual as having is severe constitute...
We present diagnostic criteria for mal de débarquement syndrome (MdDS) inclusion into the International Classification of Vestibular Disorders. The include following: 1] Non-spinning vertigo characterized by an oscillatory perception (‘rocking,’ ‘bobbing,’ or ‘swaying’) continuously most day; 2] Onset occurs within 48 hours after end exposure to passive motion, 3] Symptoms temporarily reduce with motion (e.g. driving), and 4] persist >48 hours. MdDS may be designated as “in evolution,” if...
Objective: To evaluate the association between migraine, episodic vertigo, and Ménière's disease in families. Study Design: Clinical report. Setting: University Neurotology Clinic. Patients: Index patients identified with migraine their family members. Intervention: Structured interview to assess a diagnosis of 6 Genotyping was performed on 3 sets twins analyze monozygosity or dizygosity. Main Outcome Measures: history disease. Results: Six index 57 members were interviewed either by senior...
Episodic ataxia type 1 is considered a rare neuronal ion channel disorder characterized by brief attacks of unsteadiness and dizziness with persistent myokymia. To characterize the natural history, develop outcome measures for future clinical trials, correlate genotype phenotype, we undertook an international, prospective, cross-sectional study. Thirty-nine individuals (51% male) were enrolled: median age 37 years (range 15-65 years). We identified 10 different pathogenic point mutations in...
The long-lasting neuromodulatory effects of repetitive transcranial magnetic stimulation (rTMS) are great interest for therapeutic applications in various neurological and psychiatric disorders, due to which functional connectivity among brain regions is profoundly disturbed. Classic TMS studies selectively alter neural activity specific observe changes on nonperturbed areas infer underlying its changes. Less has been indicated direct measures and/or network how connectivity/network...
Mal de Debarquement Syndrome (MdDS) is an enigmatic neurotological disorder with high morbidity, psychosocial burden, and few treatment options. Fortunately, there has been recent growth in scientific interest understanding the biological basis of treating MdDS. Recent studies using functional neuroimaging have shown increased glucose metabolism left entorhinal cortex (EC) amygdala setting decreased prefrontal temporal subjects persistent The EC a key player processing gating spatial...
Psychological theories of suicide suggest that certain traits may reduce aversion to physical threat and increase the probability transitioning from suicidal ideation action. Here, we investigated whether blunted sensitivity bodily signals is associated with action by comparing individuals a history attempted matched psychiatric reference sample without attempts. We examined interoceptive processing across panel tasks: breath-hold challenge, cold-pressor heartbeat perception during outside...
Objective Mal de debarquement syndrome (MdDS) is a chronic disorder of imbalance characterized by feeling rocking and swaying. The starts after prolonged exposure to passive motion such as from boat or plane. All medical treatment palliative symptoms that persist beyond 6 months show low likelihood remission. This pilot study explored the feasibility tolerability repetitive transcranial magnetic stimulation (rTMS) potential for MdDS. Patients/Intervention Ten subjects (8 women) with...
Background: There has there been increasing awareness that post-motion triggered of rocking self-vertigo can last for months or years, a disorder known as Mal de Debarquement Syndrome (MdDS). A similar feeling oscillating self-motion occur without motion trigger in some individuals, leading to controversy about whether motion-triggered (MT) and non (non-MT) symptoms ultimately represent the same disorder. Recognizing similarities differences between MT non-MT MdDS prevent unnecessary...
To determine whether the chronic rocking dizziness that occurs in Mal de Debarquement Syndrome (MdDS) can be suppressed with repetitive transcranial magnetic stimulation (rTMS) beyond treatment period.We performed a prospective randomized double-blind sham controlled crossover trial of 5-days rTMS utilizing high frequency (10 Hz) over left dorsolateral prefrontal cortex (DLPFC).Eight right-handed women (44.5 [SD 7.0] yr) classical motion-triggered MdDS (mean duration 42.1 13.2] mo)...
Objectives.— To describe a large multigenerational family with migraine‐associated vertigo (MAV) combining detailed phenotypic and genetic analysis. Background.— Migraine‐associated is said to be highly prevalent in the general population and, like other migraine syndromes, its etiology felt have strong component. However, so far, there been no reports of families MAV. Methods.— Detailed clinical study was conducted on Genetic using identical‐by‐descent analysis dense single nucleotide...
Background Chronic rocking dizziness, often described as the feeling of being on a boat, is classically triggered by prolonged exposure to passive motion. Patients with this motion-triggered sensation rocking, which also known mal de debarquement syndrome, develop new onset headaches along dizziness. dizziness has been noted in vestibular migraine, occurring without motion trigger. We sought clarify association between both (MT) and non-motion-triggered (non-MT) chronic headache history....
Diffusion tensor imaging (DTI) has often been used to examine white matter (WM) tract abnormalities in depressed subjects, but these studies have yielded inconsistent results, probably, due gender composition or small sample size. In this study, we applied different analysis pipelines a relatively large of individuals with depression determine whether previous findings can be replicated pipelines. We "standard" DTI algorithm and maps computed through free-water (FW) corrected DTI. This...
Abstract Transcranial direct current stimulation (tDCS) has been studied as a therapeutic option to alter maladaptive brain functions associated with chronic substance use. We present randomized, triple‐blind, sham‐controlled, clinical trial determine the neural substrates of tDCS effects on drug craving. Sixty participants methamphetamine use disorder were assigned two groups: active (5 x 7 cm 2 , mA, 20 min, anode/cathode over F4/Fp1) and sham stimulation. Neuroimaging data cue reactivity...
The authors sought to determine whether an inflammatory challenge with lipopolysaccharide (LPS) differentially impacts symptoms of anhedonia in participants major depressive disorder high (≥3 mg/L) and low (≤1.5 serum C-reactive protein (CRP) concentrations. Sixty-eight were randomly assigned, a 1:1 ratio, receive LPS (0.8 ng/kg body weight) or placebo (saline) parallel-group double-blind design. Participants stratified according baseline CRP concentrations, yielding four groups: high-CRP...
Mal de Debarquement Syndrome is a neurological disorder of motion perception, triggered by external motion. This study aimed to determine the importance psychosocial factors in relation depression and quality life Syndrome. A total 66 participants with self-reported completed quality-of-life, symptom severity, stigma, depression, illness intrusiveness measurements this naturalistic correlational study. was associated high levels intrusiveness. Illness mediated between stigma life; also level...
Individuals with Mal de Debarquement syndrome (MdDS) experience persistent oscillating vertigo lasting for months or years. Transcranial magnetic stimulation (TMS) can modulate the motion perception of MdDS.Twenty-six TMS naive individuals received single administrations continuous theta burst (cTBS) over occipital cortex, cerebellar vermis, and lateral hemisphere, in randomized order. A 0-100 point Visual Analogue Scale was used to assess acute changes severity after each session. Repeated...