A5051556037- Transcranial Magnetic Stimulation Studies
- Neural and Behavioral Psychology Studies
- Motor Control and Adaptation
- Muscle activation and electromyography studies
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Vestibular and auditory disorders
- Stroke Rehabilitation and Recovery
- Action Observation and Synchronization
- Functional Brain Connectivity Studies
- Neuroscience and Neural Engineering
- Electronic Health Records Systems
- Neurobiology of Language and Bilingualism
- Neural dynamics and brain function
- Neuroscience and Music Perception
- Biomedical Text Mining and Ontologies
- Attention Deficit Hyperactivity Disorder
- Clinical practice guidelines implementation
- Advanced Neuroimaging Techniques and Applications
- Visual perception and processing mechanisms
- Migraine and Headache Studies
- Bioinformatics and Genomic Networks
- Face Recognition and Perception
- Botulinum Toxin and Related Neurological Disorders
- Intraoperative Neuromonitoring and Anesthetic Effects
Northwestern University
2022-2025
Northwestern Medicine
2025
Lurie Children's Hospital
2023-2024
University of California, Los Angeles
2014-2023
Centre for Movement Disorders
2020
UCLA Health
2020
Brain Mapping Foundation
2007-2019
Rush University Medical Center
2017
Texas Neurology
2017
Baylor College of Medicine
2017
Background and Purpose— Functional brain imaging after stroke offers insight into motor network adaptations. This exploratory study examined whether cortical activation captured during arm-focused therapy can predict paretic hand functional gains. Methods— Eight hemiparetic patients had serial MRI (fMRI) while performing a pinch task before, midway, 2 weeks of constraint-induced therapy. The Wolf Motor Function Test (WMFT) was performed before intervention. Results— There linear reduction in...
To assess whether multifocal, high-frequency repetitive transcranial magnetic stimulation (rTMS) of motor and prefrontal cortex benefits mood symptoms in patients with Parkinson disease (PD).Patients PD depression were enrolled this multicenter, double-blind, sham-controlled, parallel-group study real or realistic (electric) sham rTMS. Patients randomized to 1 4 groups: bilateral M1 ( + dorsolateral [DLPFC]), DLPFC M1), DLPFC, double sham. The TMS course consisted 10 daily sessions 2,000...
We tested the feasibility of a computer based at-home testing device (AHTD) in early-stage, unmedicated Parkinson's disease (PD) patients over 6 months. measured compliance, technical reliability, and patient satisfaction to weekly assessments tremor, small large muscle bradykinesia, speech, reaction/movement times, complex motor control. relative UPDRS score. The AHTD is 6.5'' x 10'' computerized assessment battery. Data are stored on USB memory stick sent by internet central data...
People all over the world use their hands to communicate expressively. Autonomous gestures, also known as emblems, are highly social in nature, and convey conventionalized meaning without accompanying speech. To study neural bases of cross-cultural communication, we used single pulse transcranial magnetic stimulation (TMS) measure corticospinal excitability (CSE) during observation culture-specific emblems. Foreign Nicaraguan familiar American emblems well meaningless control gestures were...
Health literacy has come to play a critical role in health education and promotion, yet it is poorly understood adolescents few measurement tools exist. Standardized instruments measure adults assume be derivative of general literacy. This paper reports on the development early-stage validation tool for high school students that measured skills understand evaluate information. A systematic process was used develop, score validate items. Questionnaire data were collected from 275, primarily...
Article Abstract Background: Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive method that holds promise for treating several psychiatric disorders. Yet the most effective location and parameters treatment need more exploration. Also, whether rTMS an individuals with DSM-IV diagnosis of generalized anxiety disorder (GAD) has not been empirically tested. The goal this pilot study was to evaluate functional resonance imaging (fMRI)-guided in reducing symptoms GAD. Method:...
Abstract Transcranial magnetic stimulation (TMS) has become a common tool for the brain mapping of wide variety cognitive functions. Because TMS over cortical regions interest other than motor cortex often does not produce easily observable effects, ability to calibrate intensity nonmotor can be problematic. Previous studies reported no correlation between thresholds (MT) and phosphene (PT) visual cortex. However, different thresholding methods, lighting, eye‐closure conditions were used...
Abstract Practice of tasks in an interleaved order generally induces superior learning compared with practicing a repetitive order, phenomenon known as the contextual‐interference (CI) effect. Increased neural activity during over practice has been associated beneficial effects CI. Here, we used psychophysiological interaction (PPI) analysis to investigate whether connectivity dorsal premotor (PM) and dorsolateral prefrontal (DLPFC) cortices changes when motor sequences are acquired through...
Abstract Transcranial direct current stimulation (tDCS) is an emerging non-invasive neuromodulation technique that applies mA currents at the scalp to modulate cortical excitability. Here, we present a novel magnetic resonance imaging (MRI) technique, which detects fields induced by tDCS currents. This based on Ampere’s law and exploits linear relationship between fields. Following validation phantom with known path of electric field, proposed MRI was applied human limb (to demonstrate...
The elaborative-processing and forgetting-reconstruction hypotheses are the 2 principal explanations for contextual interference (CI) effect. present authors' purpose was to identify which of these better accounts CI They synchronized single transcranial magnetic stimulation (TMS) pulses each intertrial interval modulate information processing during Blocked Random Practice conditions. Participants practiced 3 arm tasks with either a or order. conditions (No TMS, Sham TMS) by 2-practice...
To determine whether the chronic rocking dizziness that occurs in Mal de Debarquement Syndrome (MdDS) can be suppressed with repetitive transcranial magnetic stimulation (rTMS) beyond treatment period.We performed a prospective randomized double-blind sham controlled crossover trial of 5-days rTMS utilizing high frequency (10 Hz) over left dorsolateral prefrontal cortex (DLPFC).Eight right-handed women (44.5 [SD 7.0] yr) classical motion-triggered MdDS (mean duration 42.1 13.2] mo)...
Cathodal transcranial direct current stimulation (C-tDCS) provides neuroprotection in preclinical models of acute ischemic stroke (AIS) by inhibiting peri-infarct excitotoxic effects and enhancing collateral perfusion due to its vasodilatory properties.To report the first-in-human pilot study using individualized high-definition (HD) C-tDCS as a treatment AIS.This randomized clinical trial was sham controlled with 3 + dose escalation design, conducted at single center from October 2018 July...
Random practice of motor tasks has been shown to enhance learning. The purpose this study was investigate the effects task order (random, blocked) on learning in adults with Parkinson disease (PD).Twenty mild PD and 20 age-matched (controls) participated study.Participants both groups (PD control) practiced 3 movement either a blocked or random order. This 2 participant group x design resulted 4 experimental groups. Trail Making Test administered all participants determine task-switching...