Diego Garcia Miranda

ORCID: 0000-0003-3804-7632
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About
Contact & Profiles
Research Areas
  • Proteoglycans and glycosaminoglycans research
  • Temporomandibular Joint Disorders
  • Laser Applications in Dentistry and Medicine
  • Oral microbiology and periodontitis research
  • Essential Oils and Antimicrobial Activity
  • Antifungal resistance and susceptibility
  • Phytochemicals and Medicinal Plants
  • Youth, Drugs, and Violence
  • Osteoarthritis Treatment and Mechanisms
  • Hydrogels: synthesis, properties, applications
  • Injury Epidemiology and Prevention
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Electrospun Nanofibers in Biomedical Applications
  • Airway Management and Intubation Techniques
  • Periodontal Regeneration and Treatments
  • Bacterial Identification and Susceptibility Testing
  • Bacterial biofilms and quorum sensing
  • Bee Products Chemical Analysis
  • Antimicrobial Peptides and Activities
  • Toxin Mechanisms and Immunotoxins
  • Insect and Pesticide Research
  • Nosocomial Infections in ICU
  • Natural Antidiabetic Agents Studies

Université Claude Bernard Lyon 1
2015-2025

Universidade Estadual Paulista (Unesp)
2023-2025

Hospices Civils de Lyon
2024-2025

Laboratoire des Multimatériaux et Interfaces
2015-2024

Centre National de la Recherche Scientifique
2015-2024

Abstract The current challenge in treating periodontitis is regenerating the periodontium. This motivates tissue‐engineering researchers to develop scaffolds as artificial matrices that give mechanical support for osteoblasts, cementoblasts, gingival and periodontal ligament fibroblast cells. In this study, modified hyaluronic acid (HA) chitosan (CS) were employed create a hybrid CS‐HA hydrogel scaffold regeneration. CS, HA, obtained by freeze‐drying technique, resulting porous structures...

10.1002/jbm.b.33516 article EN Journal of Biomedical Materials Research Part B Applied Biomaterials 2015-09-07

This study evaluates the antimicrobial activity of glycolic extract G. sylvestre against anaerobic pathogens, along with its cytotoxicity, genotoxicity, anti-inflammatory activity, antioxidant effects, and phytochemical composition. Phytochemical analysis was conducted using high-performance liquid chromatography chromatography-mass spectrometry, while effect assessed through a DPPH assay. Antimicrobial action tested on planktonic cultures biofilms Porphyromonas gingivalis, endodontalis,...

10.3390/plants14040497 article EN cc-by Plants 2025-02-07

(1) Background: In hospitals, medical and dental clinics, antiseptics or disinfectants play an essential role in the control of nosocomial infections. This study aimed to evaluate R. officinalis P. paniculata glycolic extracts regarding: (I) their antimicrobial action on planktonic biofilm (monotypic cutaneous model—S. aureus, S. epidermidis C. acnes); (II) cytotoxicity human keratinocytes (HaCaT). (2) Methods: Minimum inhibitory concentration (MIC) minimum bactericidal (MBC) were performed...

10.3390/antibiotics13030226 article EN cc-by Antibiotics 2024-02-28

The World Health Organization (WHO) has prioritized developing new drugs against specific bacteria and fungi, such as Enterobacteriaceae Candida spp. While Pfaffia paniculata is commonly called the “cure-everything”, its scientifically proven benefits are limited to anti-inflammatory antioxidant actions. Therefore, this study aims determine spectrum of antimicrobial activity assess cytotoxicity. Thus, broth microdilution test was conducted according CLSI M7-A9 M27-A3 reference methods. After...

10.3390/microorganisms12061165 article EN cc-by Microorganisms 2024-06-08

Temporomandibular disorders (TMD) are a public health problem that affects around 12% of the global population. The treatment is based on analgesics, non-steroidal anti-inflammatory, corticosteroids, anticonvulsants, or arthrocentesis associated with hyaluronic acid-based viscosupplementation. However, use acid alone in viscosupplementation does not seem to be enough regulate intra-articular inflammatory process. So, we propose develop and evaluate physicochemical biological properties vitro...

10.3390/gels10120811 article EN cc-by Gels 2024-12-10

Abstract Antimicrobial resistance is a worldwide health problem and patients in intensive care are more vulnerable, requiring strict control measures early identification. Currently, clinical culture materials used to identify the bacterial agent, but saliva not validated, which has great relevance because it participates several pathophysiological processes. The aim of this study was validate an unit environment, determining its diagnostic value for infection. For purpose, results 39-month...

10.1038/s41598-023-47143-3 article EN cc-by Scientific Reports 2023-11-20

10.29327/155319.2-2 article PT Anais do Congresso Acadêmico de Especialidades Médicas da Universidade Anhembi Morumbi Campus São José dos Campos. 2022-01-01

Anais do Congresso Acadêmico de Especialidades Médicas da Universidade Anhembi Morumbi campus São José dos Campos (2764-3565) - Intubação Submentoniana Para Manejo De Via Aérea Em Paciente Politraumatizado Face

10.29327/155319.2-3 article PT Anais do Congresso Acadêmico de Especialidades Médicas da Universidade Anhembi Morumbi Campus São José dos Campos. 2022-01-01
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