- Substance Abuse Treatment and Outcomes
- Opioid Use Disorder Treatment
- Prenatal Substance Exposure Effects
- Attention Deficit Hyperactivity Disorder
- Child and Adolescent Psychosocial and Emotional Development
- Cannabis and Cannabinoid Research
- Mental Health Treatment and Access
- Pharmaceutical Practices and Patient Outcomes
- Digital Mental Health Interventions
- Neuroethics, Human Enhancement, Biomedical Innovations
- Health Policy Implementation Science
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Behavioral and Psychological Studies
- Smoking Behavior and Cessation
- Alcohol Consumption and Health Effects
- Pharmaceutical studies and practices
- Transcranial Magnetic Stimulation Studies
- Poisoning and overdose treatments
- Mobile Health and mHealth Applications
- HIV, Drug Use, Sexual Risk
- Breastfeeding Practices and Influences
- Neural and Behavioral Psychology Studies
- Health Systems, Economic Evaluations, Quality of Life
- Adolescent and Pediatric Healthcare
National Institute on Drug Abuse
2016-2025
National Institutes of Health
2010-2025
SEGi University
2024
M. Kumarasamy College of Engineering
2024
INTI International University
2024
Centre for Nursing Innovation
2024
Johns Hopkins University
2001-2017
Johns Hopkins Medicine
2010-2017
University of Maryland, College Park
2016
Friends Research Institute
2016
<h3>Context</h3>The usual treatment for opioid-addicted youth is detoxification and counseling. Extended medication-assisted therapy may be more helpful.<h3>Objective</h3>To evaluate the efficacy of continuing buprenorphine-naloxone 12 weeks vs youth.<h3>Design, Setting, Patients</h3>Clinical trial at 6 community programs from July 2003 to December 2006 including 152 patients aged 15 21 years who were randomized or a 14-day taper (detox).<h3>Interventions</h3>Patients in 12-week group...
Background: Substance use, a leading cause of illness and death, is underidentified in medical practice. Objective: The Tobacco, Alcohol, Prescription medication, other use (TAPS) tool was developed to address the need for brief screening assessment instrument that includes all commonly used substances fits into clinical workflows. goal this study assess performance TAPS primary care patients. Design: Multisite study, conducted within National Drug Abuse Treatment Clinical Trials Network,...
The application of digital technologies to better assess, understand, and treat substance use disorders (SUDs) is a particularly promising vibrant area scientific research. National Drug Abuse Treatment Clinical Trials Network (CTN), launched in 1999 by the U.S. Institute on Abuse, has supported growing line research that leverages glean new insights into SUDs provide science-based therapeutic tools diverse array persons with SUDs.This manuscript provides an overview breadth impact conducted...
Opioid dependence is an increasing problem among adolescents and young adults, but in contrast to the standard adult population, adoption of pharmacotherapies has been slow. Extended-release naltrexone (XR-NTX) a promising treatment that receiving interest for opioid dependence. Clinical chart abstractions were performed on convenience sample 16 serial adolescent cases (mean age 18.5 years) treated with XR-NTX who attended at least one out-patient clinical follow-up visit.Of these cases, 10...
The objective is to estimate cost, net social cost and cost-effectiveness in a clinical trial of extended buprenorphine-naloxone (BUP) treatment versus brief detoxification opioid-dependent youth.Economic evaluation conducted at six community out-patient programs from July 2003 December 2006, who were randomized 12 weeks BUP or 14-day taper (DETOX). patients prescribed up 24 mg per day for 9 then tapered zero the end week 12. DETOX 14 on 14. All offered twice-weekly drug counseling.152 aged...
Importance Efficient screening tools that effectively identify substance use disorders (SUDs) among youths are needed. Objective To evaluate the psychometric properties of 3 brief (Screening to Brief Intervention [S2BI]; Screener for Tobacco, Alcohol, and Drugs [BSTAD]; Prescription Medication, Other Substances [TAPS]) with adolescents aged 12 17 years. Design, Setting, Participants This cross-sectional validation study was conducted from July 1, 2020, February 28, 2022. years were recruited...
ABSTRACT Aims Electronic health records (EHRs) are essential in improving quality and enhancing efficiency of health‐care delivery. By 2015, medical care receiving service reimbursement from US Centers for Medicare Medicaid Services (CMS) must show ‘meaningful use’ EHRs. Substance use disorders (SUD) grossly under‐detected under‐treated current settings. Hence, an urgent need exists improved identification clinical intervention SUD The National Institute on Drug Abuse Clinical Trials Network...
There are limited data about the extent of DSM-5 substance use disorders (SUDs) among primary care patients. This study analyzed from a multisite validation screening instrument conducted in diverse sample 2000 adults aged ≥18 years recruited five practices four states. Prevalence and correlates 12-month SUDs were examined. Overall, 75.5% used any substance, including alcohol (62.0%), tobacco (44.1%), or illicit drugs/nonmedical medications (27.9%) past 12 months (marijuana 20.8%, cocaine...
To examine whether an Internet-based learning module and small-group debriefing can improve medical trainees' attitudes communication skills toward patients with substance use disorders (SUDs).In 2011-2012, 129 internal family medicine residents 370 students at two schools participated in a cluster randomized controlled trial, which assessed the effect of adding two-part intervention to SUDs curricula. The included self-directed, media-rich small-group, faculty-led debriefing. Primary study...
Preliminary test of a manualized, measurement-guided treatment for depression adolescents and young adults in care at 4 sites the Adolescent Trials Network HIV/AIDS Interventions. The US were randomly assigned to either 24-week, combination cognitive behavioral therapy medication management algorithm (COMB) tailored youth living with HIV (YLWH) or as usual (TAU). Youth TAU had access therapists needed. COMB-site clinicians trained manualized intervention participated supervision calls...
Abstract Background The TAPS Tool is a substance use screening and brief assessment instrument that was developed for in primary care medical settings. It one of the first instruments to provide rapid all commonly used classes, including illicit prescription opioids, only available screeners designed validated an electronic self-administered format (myTAPS). This secondary analysis data from validation study describes feasibility acceptability myTAPS among patients. Methods Adult patients (N...