The search for neuroprotective compounds in lavender is driven by its traditional use brain health, with antioxidant activity serving as a key mechanism reducing oxidative stress and supporting cognitive function. Lavender’s potential to protect neurons based on calming, anti-stress properties, which increase the brain’s resistance neurodegeneration. Although not medicinal plant Ukraine, it increasingly recognised properties widely cultivated country. Lavender Ukraine influenced both global...

Climate change and human activities severely impact the viability of plants ecosystems, threatening environment, biodiversity, sustainable development plant-based products. Biotic abiotic (ecosystem) determinants affect species distribution long-term survival, which in turn influence quality used as herbal medicines other high-value In recent decades, diverse anthropogenic impacts have significantly affected these aspects. change, excessive plant exploitation, habitat loss, vulnerability,...

It is important to conduct studies on the influence of environmental factors accumulation secondary metabolites in plants, as well cultivation plants and harvesting their raw material.In this study, we examined habitat types, soil composition, climatic altitude content phenolic compounds Iris species from different populations Latvia, Lithuania Ukraine.According high-performance liquid chromatography (HPLC) analysis, 25 (flavonoids, isoflavonoids, isoflavonoid glucosides, xanthones,...

The major groups of antioxidant compounds (isoflavonoids, xanthones, hydroxycinnamic acids) in the rhizome methanol extracts four Ukrainian Iris sp. (Iris pallida, hungarica, sibirica, and variegata) were qualitatively quantitatively analyzed using HPLC-DAD UPLC-MS/MS. Gallic acid, caffeic mangiferin, tectoridin, irigenin, iristectorigenin B, irisolidone, 5,6-dihydroxy-7,8,3′,5′-tetramethoxyisoflavone, irisolidone-7-O-β-d-glucopyranoside, germanaism nigricin recognized by comparing their...

The aim of the work: Justification composition emulsion cream with extracts Lespedeza bicolor. Materials and methods: In development base cream, corn oil (Ukraine), propylene glycol (Germany), purified water, emulsifiers: xyliance (France), prolipid 141 (USA) lamecrem (France) were used. included liquid alcohol extract above-ground part bicolor, which obtained from harvested in Botanical Garden Ivan Franko National University Lviv (Lviv, Ukraine) flowering phase. studies used physicochemical...

The aim of the work: research on development and standardization an aqueous extract aerial part Lespedeza bicolor study pharmacotechnological parameters a gel with mangiferin. Materials methods: in studies obtaining extract, bicolor, harvested Botanical Garden Ivan Franko National University Lviv (Lviv, Ukraine) flowering phase, was used. Identification quantitative content biologically active compounds experimental samples extracts were carried out by chemical reactions, thin-layer...

Abstract: Green tea is a traditional drink found in Asian countries, made up of four derivatives. One the derivatives epigallocatechin-3-gallate (EGCG). EGCG provides therapeutic benefits for cancer, heart disease, diabetes, and obesity. However, its poor absorption instability limit effectiveness, which can be improved using nanoparticle encapsulation. This work comprehensive review studies on green polyphenols, impact pro-oxidants cancer prevention, their delivery nanotechnology. Other...

Crocus sativus L. is one of the world’s most famous saffron production crops and its enormous by-products, such as leaves, are an excellent source bioactive compounds with potential nutritional applications. The total phenolic content leaves was 5.44 ± 0.01 mg GAE/g, flavonoid 2.63 0.05 RE/g, respectively. main in polyphenols, flavonoids by HPLC carboxylic acids, amino were also identified GC-MS. analyses revealed mangiferin a dominant constituent (1.26 0.02 mg/g). C. contains seven...

Abstract Background Saffron or stigmas of Crocus sativus L. is one the most valuable food products with interesting health-promoting properties. C. has been widely used as a coloring and flavoring agent. Stigmas secondary metabolites showed potent cytotoxic effects in previous reports. Methods The present study investigated chemical composition effect Ukrainian saffron crude extracts individual compounds against melanoma IGR39, triple-negative breast cancer MDA-MB-231, glioblastoma U-87 cell...

The article examines modern theoretical and practical features of insurance defines its role functions in the economy state; place health financing system state is revealed; a conceptual approach to organization care on basis medical was developed; analyzed qualitative quantitative signs effective financial support healthcare industry by determining level Ukraine; voluntary as an element assessed; impact socio-economic factors potential social market investigated. degree development...

Iris pallida Lam kurutulmuş rizom ve yapraklarından elde edilen esansiyel yağın nitel nicel bileşimi Ukrayna'dan ilk kez okundu.Gereç Yöntemler: Buhar distilasyonuyla uçucu yağlar, gaz kromatografisi-kütle spektrometresi ile araştırıldı

The aim of this research was the comparative study amino acids content in dry extracts Iridaceae plants Ukrainian flora: Juno bucharica leaves and corms, Gladiolus hybrid Zefir leaves, Iris hungarica variegata rhizomes, Crocus sativus stigmas, flowers, corms. A gas chromatography–mass spectrometry (GC–MS) method has been used. Separation samples carried out using a Shimadzu GC-MS-QP2010 equipped with an Rxi-5ms (Restek Corporation capillary column (30 m long, 0.25 mm outer diameter µm)...

The beneficial health properties of organic acids make them target compounds in multiple studies. This is the reason why developing a simple and sensitive determination investigation method priority. In this study, an effective has been established for (lactic, glycolic, malic) saffron stigmas. N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide (MTBSTFA) was used as derivatization reagent gas chromatography combined with mass spectrometric detection (GC/MS). stigmas extract evaporated to...

Lavandula L. genus plants have always been relevant as medicines for various purposes in food, medicine, pharmaceuticals, cosmetology and aromology. Ukraine is a new territory the mass plant cultivation lavender essential oil production. Therefore, issue of integrated use herbal raw materials their intended still relevant. For first time, ten samples Lavendula angustifolia herb from 5 growing regions were studied composition content polyphenols terpenoids using HPLC HPTLC methods,...

The chemical compositions of 15 saffron samples from 11 countries (Morocco, India, Italy, Spain, Germany, Switzerland, Iran, Lithuania, Ukraine, Australia, and Azerbaijan) were evaluated. analyzed regarding the impact environmental factors on composition apocarotenoids phenolic constituents. Quantification metabolites was carried out using high-performance liquid chromatography. It found that high content chlorogenic acid (0.2 mg/g, Ukraine) ferulic (0.28 India) controlled by duration solar...

Objetivo: El objetivo del trabajo es el aislamiento y la identificación de los compuestos fenólicos losrizomas Iris hungarica.Materiales métodos: Se utilizaron métodos químicos espectrales para conocer las estructuras compuestosfenólicos que se aislaron rizomas hungarica Waldst. et Kit. (Familia Iridaceae).Los obtuvieron mediante cromatografía en columna sobre gel sílice determinaronsus análisis sus espectros por UV, IR, MS, 1H-RMN. determinó cribadopreliminar actividad...

The application of the Quality by Design (QbD) concept to extracts obtained from Crocus sativus perianth with potential anticancer activity will ensure safety, efficiency, and quality control entire technological process, as well determine critical factors affecting extracts. Potentially points production plant extracts, including cultivation processing materials, extraction choice solvents, were identified using Ishikawa diagram FMEA risk assessment methods corrective actions proposed....

The composition of secondary metabolites undergoes significant changes in plants depending on the growth phase and influence environmental factors. Therefore, it is important to determine harvesting time plant material for optimum metabolite profile therapeutic activity primary material. shoots Epilobium angustifolium are used as a healing tea due presence polyphenolic compounds. aim this study was assess phenolic compounds triterpenoid saponins E. leaves flowers estimate dynamics their...

Crocus sativus L. (saffron) has been traditionally used as a food coloring or flavoring agent, but recent research shown its potent pharmacological activity to tackle several health-related conditions. sp. leaves, and petals are the by-products of saffron production not usually in medicine industries. The present study was designed determine chemical composition water ethanolic extracts C. leaves test their cytotoxic against melanoma (IGR39) triple-negative breast cancer (MDA-MB-231) cell...

Ion association of glycine, \a-alanine and \�-alanine in water water+ D-glucose mixtures at different temperaturesSanjibita Das Upendra N. Dash

Abstract: The average worldwide human life expectancy is 70 years, with a significantly higher value in Western societies. Many modern diseases are not associated premature mortality but decreased quality of aged patients and an excessive accumulation various toxic compounds the body during life. Today, scientists especially interested finding that can help increase healthy lifespan by detoxifying body. Phytotherapy specific approaches used alternative medicine to remove toxins from...