A5061278838- Medicinal plant effects and applications
- Phytochemicals and Antioxidant Activities
- Phytochemical and Pharmacological Studies
- Agriculture and Biological Studies
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Biological Activities
- Genomics, phytochemicals, and oxidative stress
- Herbal Medicine Research Studies
- Free Radicals and Antioxidants
- Bee Products Chemical Analysis
- Polysaccharides and Plant Cell Walls
- Scientific Research and Studies
- Synthesis and Characterization of Heterocyclic Compounds
- Food Quality and Safety Studies
- Natural product bioactivities and synthesis
- RNA regulation and disease
- Antioxidant Activity and Oxidative Stress
- Arsenic contamination and mitigation
- Aluminum toxicity and tolerance in plants and animals
- Phytochemicals and Medicinal Plants
- Synthesis and biological activity
- Liver Disease Diagnosis and Treatment
- Silymarin and Mushroom Poisoning
- Essential Oils and Antimicrobial Activity
- Toxin Mechanisms and Immunotoxins
National University of Pharmacy
2014-2024
Berberine is the main active compound of different herbs and defined as an isoquinoline quaternary botanical alkaloid found in barks roots numerous plants. It exhibits a wide range pharmacological effects, such anti-obesity antidiabetic effects. has antibacterial activity against variety microbiota, including many bacterial species, protozoa, plasmodia, fungi, trypanosomes.
Abstract: The average worldwide human life expectancy is 70 years, with a significantly higher value in Western societies. Many modern diseases are not associated premature mortality but decreased quality of aged patients and an excessive accumulation various toxic compounds the body during life. Today, scientists especially interested finding that can help increase healthy lifespan by detoxifying body. Phytotherapy specific approaches used alternative medicine to remove toxins from...
Qualitative composition and content of phenolic compounds in the liquid extract obtained from plum fruits have been studied.Five substances were found, as gallic acid, three hydroxycinnamic acids rutin.The dominant substance was neochlorogenic acid (2320±42 mg/kg).Phenolic identified their amount determined by HPLC.Diuretic activity diurnal spontaneous diuresis forced diuresis, hypouricosemic membrane-stabilizing effects its influence on rheological properties blood studied.
Aim. The aim of our research was fractionation polysaccharide complexes from fresh plum fruits, comparative study content neutral sugars in it, element composition fruit and investigation influence fibers water soluble complex (WSPC) on histostructure rats liver conditions ethanol intoxicationMethods. elemental determined with atomic emission spectrophotometer ISE 3500 (Thermo Scientific, USA). fractions as fibers, WSPC pectin by Gravimetry. monosaccharides obtained carried out picric acid...
Qualitative composition and content of biologically active compounds in the peach leaves 50% ethanol extract obtained from have been studied. The total phenolic compounds, determined by spectrophotometry was as 3,17±0,15 %; tannins – 1,02±0,05 amounts flavonoids 2,54±0,12 % hydroxycinnamic acids 1,59±0,07 %. qualitative studied with HPLC using an Agilent Technologies chromatograph (model 1100) equipped a continuous-flow vacuum degasser G1379A, 4-channel low-pressure gradient pump G13111A,...
Medicines on the basis of herbs are increasingly used for treating many diseases and provide following actions laxative, hepatoprotective, membrane stabilizing antimicrobial. The plant <i>Prunus domestica</i> L., family <i>Rosaceae</i> is widely cultivated worldwide. recent studies have shown that fruits antioxidant, anticancer, antihyperglycemic, anti-hyperlipidemic, antihypertensive, antiosteoporosis, laxative hepatoprotective activities. As raw material plum Ukrainian variety 'vengerka'...
The chemical composition and pharmacological activity of the dry extract based on herbal tea composed black horehound (Ballota nigra) herb, white nettle (Lamium album) wormwood (Artemisiae absinthii) herb in equal amounts have been studied. As a result study main groups biologically active substances its basis presence phenolic compounds such as derivatives hydroxycinnamic acid, hydroxycoumarins, flavonoids their quantitative content determined. In research objects aglycons (luteolin,...
Introduction: Water pollution with antibiotics plays a key role in the formation and spread of antibiotic resistance, which threatens humanity environment as whole. Aim: The purpose our work was to develop method for determining azithromycin wastewater surface water using thin-layer chromatography method. Materials Methods: developed technique tested Zolochiv district Kharkiv region. Results Discussion: Using conventional analytical scales universal thin layers sorbent, it is possible...
The study of pharmacological properties and experimental substantiation application possibilities the plum fruits extracts in treatment gastrointestinal tract hepatobiliary system diseases is relevant, because source phenolic compounds with a wide range action used folk medicine for treating digestive system. aim present work was an anti free radical activity by lipid peroxidation indicators antioxidant (AOS) two Plum extracts, detecting most effective extract determining its dose. objects...
Ledum palustre shoots (Cormus Ledi palustri) hase long been used as an antispasmodic, diuretic, diaphoretic, disinfectant, anti-inflammatory, sedative and antitussive remedy in folk medicine. The most studied are terpene compounds, they component of essential oil, medicine "Ledin" with effect was developed on their basis, While the polysaccharide complex this plant is almost not studied. aim our research investigation (PSC) obtained from determination its pharmacological activities. PSC...
Labrador tea shoots has long been used in folk medicine as an antispasmodic, diuretic, diaphoretic, disinfectant, anti-inflammatory, soothing and antitussive remedy. In general it is due to the presence of terpene compounds, phenoliccompounds, tannins other substances plant material. “Ledin” was only one that produced from this raw It based on essential oil But for now, just packed materials remain drugstores shelves. That why necessary obtain standardized, dry extract We have already...
Aim. To study saponins of the raspberry cake ethanol extract.Materials and methods. The object was extract obtained from Rubus idaeus fruit. saponin compounds carried out by HPLC.Results discussion. following were found in extract: euscapic acid (0.24 %), tormentic (0.14 lupeol (0.65 %). These are interest to pharmacy medicine as substances with oncoprotective hepatoprotective activity.Conclusions. qualitative quantitative composition fruits has been studied. results indicate prospects...
The treatment of infectious diseases is one the global problems modern medicine. Despite large amount medications problem creation new highly effective antimicrobials a relevant task. This is, mainly, due to increase microbial resistance widely used antimicrobials. One promising ways solve this task search and antimicrobial substances.Aim. To for substances with activity among derivatives morpholine-containing 2-R-phenyliminothiazole, namely...
Topicality. Most of the respiratory diseases are accompanied by cough. In addition, many etiological cough factors associated with inflammatory process.Aim. To investigate anti-inflammatory properties new Ledum palustre shoots polysaccharides complex at most effective dose (100 mg/kg).Materials and methods. Experimental investigations usual 100 mg/kg on model carrageenan zymosan edema in rats.Results discussion. According to results study, mechanism anti-exudative action first obtained was...
Prunus domestica - is one of the main fruit crops in Ukraine with a production about 200 tons per year. In world over then 2000 varieties this plant are grown. Ukraine, following plums zoned: Anna Shpet, Renklod Altana, Ugorka Stanley, Italian, Azhanska, and others. This valuable source polysaccharides phenolic compounds. That why plum fruits part many dietary supplements laxative anti-inflammatory activity treating chronic constipation. our previous research, we studied chemical composition...
The aim of the experiment was to study anti-inflammatory effect novogalene agent Ledum 50, obtained from palustre shoots, in a rat model acute bronchitis.
 Materials and methods. Acute bronchitis initiated by endotracheal administration 1 % formalin solution. effectiveness 50 investigated number leukocytes cell composition isotonic BAL solution after 24 hours 8 days experiment. Serum levels C-reactive protein (CRP), alkaline phosphatase (AP) CIC were determined. Histological examination...