Li Ding

ORCID: 0000-0003-3851-5504
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About
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Research Areas
  • Analytical Chemistry and Chromatography
  • Nanoplatforms for cancer theranostics
  • Plasmonic and Surface Plasmon Research
  • Analytical chemistry methods development
  • Photonic and Optical Devices
  • MXene and MAX Phase Materials
  • Toxic Organic Pollutants Impact
  • Mass Spectrometry Techniques and Applications
  • Semiconductor materials and interfaces
  • Effects and risks of endocrine disrupting chemicals
  • 2D Materials and Applications
  • Optical Coatings and Gratings
  • Membrane Separation Technologies
  • Advanced Nanomaterials in Catalysis
  • Pesticide Residue Analysis and Safety
  • Near-Field Optical Microscopy
  • Silicon and Solar Cell Technologies
  • Perovskite Materials and Applications
  • Traditional Chinese Medicine Analysis
  • Ionic liquids properties and applications
  • Nanofabrication and Lithography Techniques
  • Advancements in Photolithography Techniques
  • Quantum Dots Synthesis And Properties
  • Analytical Methods in Pharmaceuticals
  • Photonic Crystals and Applications

Washington University in St. Louis
2025

Shanghai Cancer Institute
2025

Renji Hospital
2025

Shanghai Jiao Tong University
2025

Tongji University
2022-2024

Shanghai Tenth People's Hospital
2022-2024

Shandong University of Technology
2024

Anhui University
2022

Shanghai Institute of Ceramics
2019-2021

Chinese Academy of Sciences
2006-2021

Abstract Nanoscale plasmonic assemblies display exceptionally strong chiral optical activity. So far, their structural design was primarily driven by challenges related to metamaterials whose practical applications are remote. Here we demonstrate that gold nanorods assembled the polymerase chain reaction into DNA-bridged systems have promising analytical applications. The chiroplasmonic activity of side-by-side patterns is attributed a 7–9 degree twist between nanorod axes. This results in...

10.1038/ncomms3689 article EN cc-by Nature Communications 2013-10-28

Reactive oxygen species (ROS) are generated and consumed in living organism for normal metabolism. Paradoxically, the overproduction and/or mismanagement of ROS have been involved pathogenesis progression various human diseases. Here, we reported a two-dimensional (2D) vanadium carbide (V2C) MXene nanoenzyme (MXenzyme) that can mimic up to six naturally-occurring enzymes, including superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), glutathione (GPx), thiol (TPx) haloperoxidase...

10.1038/s41467-021-22278-x article EN cc-by Nature Communications 2021-04-13

Nanocatalytic medicine has been developed recently to trigger intratumoral generation of highly toxic reactive oxygen species (ROS) for cancer therapy, which, unfortunately, suffers from compromised therapeutic efficacy due a self-protective mechanism, autophagy, cells mitigate oxidative damage. In this work, during the efforts ROS by nanocatalytic medicine, pharmacological autophagy inhibition strategy is implemented augmenting ROS-induced damage synergetic therapy. An iron-containing...

10.1002/adma.201907152 article EN Advanced Materials 2020-02-13

Abstract The explosion of emerging high‐performance 2D MXenes in theranostic nanomedicine is still at the preliminary stage. Despite tremendous efforts devoted to photonic tumor hyperthermia, current photothermal‐conversion nanoagents suffer from critical issues preventing further clinical translation such as low biodegradability. Here, for first time, construction novel molybdenum carbide (Mo 2 C) hyperthermia reported. structure both bulk Mo Ga C ceramic and MXene fully revealed....

10.1002/adfm.201901942 article EN Advanced Functional Materials 2019-04-01

Atherosclerosis, driven by chronic inflammation in the artery walls, underlies several severe cardiovascular diseases. However, currently available anti-inflammatory-based strategies for atherosclerosis treatment suffer from compromised therapeutic efficacy and undesirable outcome. Herein, a distinct tetrapod needle-like PdH nanozyme was designed engineered efficient combinatorial reactive oxygen species (ROS) scavenging, hydrogen anti-inflammation, autophagy activation. After loading into...

10.1021/acsnano.2c03422 article EN ACS Nano 2022-10-11

The anticancer mechanism of nanozymes is dominantly associated with the capacity for generation reactive oxygen species (ROS) caused by valence change metal elements. However, very little research focused on and has achieved exploration development enzyme-mimicking activities valence-invariable compounds. Herein, a distinct calcium fluoride (CaF2 ) nanozyme ultrasound (US)-enhanced peroxidase (POD)-mimicking activity rationally designed engineered efficient (Ca2+ )-overload-enhanced...

10.1002/adma.202205680 article EN Advanced Materials 2022-09-15

Silicon/organic heterojunction solar cells (HSCs) based on conjugated polymers, poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), and n-type silicon (n-Si) have attracted wide attention due to their potential advantages of high efficiency low cost. However, the state-of-the-art efficiencies are still far from satisfactory inferior junction quality. Here, facile treatments were applied by pretreating n-Si wafer in tetramethylammonium hydroxide (TMAH) solution using a...

10.1021/acsnano.6b07511 article EN ACS Nano 2016-12-07

Molecularly imprinted polymer (MIP) coated Fe3O4 nanoparticles (Fe3O4@MIP) were synthesized by atom transfer radical polymerization (ATRP) and used as highly selective magnetic solid-phase extraction (MSPE) sorbents for trace bisphenol A (BPA) from packed food. The morphological polymeric characteristics of the Fe3O4@MIP characterized transmission electron microscopy Fourier transform infrared spectroscopy. In this work, competitive recognition compounds (4-n-octylphenol diglycidyl ether)...

10.1039/c1ay05206c article EN Analytical Methods 2011-01-01

A strain-tunable WSe<sub>2</sub>–CdS mixed-dimensional vdWs heterointerface is demonstrated and the photoresponse dramatically enhanced with piezo-phototronic effect.

10.1039/c8nr04376k article EN Nanoscale 2018-01-01

Abstract A simple and sensitive method was developed validated for the simultaneous determination of 103 pesticide residues in tea by LC‐MS/MS. For analysis with polarity, thermal lability or low volatility, this LC‐MS/MS has an advantage over GC. In work, residual pesticides were extracted from sample ACN then purified using Carb‐NH 2 SPE cartridges. Using multiple reaction monitoring mode, quantified identified most abundant characteristic fragment ions. The recoveries obtained each ranged...

10.1002/jssc.200800605 article EN Journal of Separation Science 2009-04-27

The magnetic multiwalled carbon nanotube (MWCNT-MNP) was successfully synthesized. MWCNT-MNP and gas chromatography-tandem mass spectrometry (GC-MS/MS) were used for rapid, simple reliable determination of bisphenol A (BPA), F (BPF), diglycidyl ether (BFDGE) (BADGE) at trace levels in water. major factors affecting the recovery efficiency, such as amount MWCNT-MNP, pH water sample volume, carefully investigated. these compounds range 88.5–115.1% with relative standard deviation less than...

10.1039/c1ay05433c article EN Analytical Methods 2011-12-06

The size of an ion affects everything from the structure water to life itself. In this report, gauge their size, ions dissolved in are forced electrically through a sub-nanometer-diameter pore spanning thin membrane and current is measured. measurements reveal ion-selective conductance that vanishes pores <0.24 nm diameter-the molecule-indicating permeating have grossly distorted hydration shell. Analysis noise power spectral density exposes threshold, below which independent current, beyond...

10.1038/s41467-019-10265-2 article EN cc-by Nature Communications 2019-05-30

A magnetic solid phase extraction method coupled to gas chromatography–tandem mass spectrometry was proposed for the determination of phthalate esters at trace levels in drinking water. The multi-walled carbon nanotubes were prepared and applied as sorbents extraction. major factors affecting recovery efficiency, such amount nanotubes, pH water sample, desorption conditions extracting time carefully investigated. these compounds range 86.6–100.2% with a relative standard deviation (RSD)...

10.1039/c2ay25386k article EN Analytical Methods 2012-01-01

Abstract A simple and sensitive method was developed for determination of illegal adulterants (yohimbine, sildenafil, vardenafil tadalafil) in dietary supplements by HPLC‐MS/MS. The separation achieved on a C 18 column with the mobile phase consisting acetonitrile 0.1% acetic acid aqueous solution gradient elution at flow rate 0.5 mL/min. analytes were quantified identified two characteristic transitions using multiple‐reaction monitoring mode. recoveries ranged from 77.5 to 109.3% RSD less...

10.1002/jssc.200900841 article EN Journal of Separation Science 2010-06-07

PFN is introduced to the Al/n-Si interface improve contact quality by reducing work function of Al electrode, getting an ohmic contact. An excellent photovoltaic efficiency 13.35% has been achieved in a planar device with layer.

10.1039/c5ra26152j article EN RSC Advances 2016-01-01

In 2-D van der Waals heterostructures, interactions between atomic layers dramatically change the vibrational properties of hybrid system and demonstrate several interesting phenomena that are absent in individual materials. this paper, we have investigated heterostructure transition metal dichalcogenide (TMD) hexagonal boron nitride (hBN) on gold film at low- high-frequency ranges by Raman spectroscopy. Nineteen modes been observed from sample, including a new interlayer coupling mode 28.8...

10.1109/ted.2018.2847230 article EN publisher-specific-oa IEEE Transactions on Electron Devices 2018-07-10

Multi-omic data-driven studies are at the forefront of precision medicine by characterizing complex disease signaling systems across multiple views and levels. The integration interpretation multi-omic data critical for identifying targets deciphering pathways. However, it remains an open problem due to interactions among many proteins. Herein, we propose a multi-scale multi-hop network flow model, M3NetFlow, facilitate both hypothesis-guided generic analysis tasks. We evaluated M3NetFlow...

10.1016/j.isci.2025.111920 article EN cc-by-nc iScience 2025-02-06

Abstract Aristolochic acid derivatives (AAs) and aristolactam (ALs) have been characterized by electrospray ionization mass spectrometry, their fragmentation pathways are proposed. ALs exhibit a single product [M+H] + , whereas AAs show multiple products. By optimizing the chromatographic separation spectrometric parameters, precursor ions of with best responses were found, sensitivities in determination nine improved. Based on investigation behaviour, HPLC‐DAD/ESI‐MS (high‐performance...

10.1002/rcm.3097 article EN Rapid Communications in Mass Spectrometry 2007-06-18
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