A5102876479- Analytical Chemistry and Sensors
- Advanced biosensing and bioanalysis techniques
- Gas Sensing Nanomaterials and Sensors
- Epigenetics and DNA Methylation
- Electrochemical Analysis and Applications
- Optical Systems and Laser Technology
- Ferroptosis and cancer prognosis
- Electrochemical sensors and biosensors
- Advanced Chemical Sensor Technologies
- Biosensors and Analytical Detection
- Liver physiology and pathology
- Adaptive optics and wavefront sensing
- Heat Transfer and Boiling Studies
- Bioinformatics and Genomic Networks
- Blood Coagulation and Thrombosis Mechanisms
- Laser Material Processing Techniques
- Platelet Disorders and Treatments
- Virology and Viral Diseases
- Optical Coatings and Gratings
- Antibiotics Pharmacokinetics and Efficacy
- Advanced optical system design
- biodegradable polymer synthesis and properties
- Virus-based gene therapy research
- Atherosclerosis and Cardiovascular Diseases
- Blood groups and transfusion
Beihua University
2024-2025
Shanghai Normal University
2023-2024
Changchun Institute of Optics, Fine Mechanics and Physics
2022-2024
Chinese Academy of Sciences
2021-2024
Shanghai University
2024
University of Chinese Academy of Sciences
2022
Center for Excellence in Molecular Cell Science
2021
Bioscience (China)
2011
Michigan State University
1999-2004
Nanyang Technological University
2001
Abstract Liver cirrhosis remains major health problem. Despite the progress in diagnosis of asymptomatic early-stage cirrhosis, prognostic biomarkers are needed to identify cirrhotic patients at high risk developing advanced stage disease. is result deregulated wound healing and featured by aberrant extracellular matrix (ECM) remodeling. However, it not comprehensively understood how ECM dynamically remodeled progressive development liver cirrhosis. It yet unknown whether signature...
Florfenicol (FF) raises significant human health and environmental concerns due to its toxicity the hematology system potential spread of antibiotic-resistant genes. Here, a highly sensitive molecularly imprinted photoelectrochemical (PEC) sensor, featuring an In2O3/Bi2S3 S-scheme heterojunction, is proposed detect FF without external voltage supply. Compared with conventional II-type heterojunctions, heterojunctions efficiently promote carrier separation enhance redox capability...
Background The rising incidence of breast cancer and its heterogeneity necessitate precise tools for predicting patient prognosis tailoring personalized treatments. Epigenetic changes play a critical role in progression therapy responses, providing foundation prognostic model development. Methods We developed the Machine Learning-derived Model (MLEM) to identify epigenetic gene patterns cancer. Using multi-cohort transcriptomic datasets, MLEM was constructed with rigorous machine learning...
Conventional photoelectrochemical (PEC) biosensors suffer from the difficulty of visualizing rapid detection and limited accuracy due to a single-signal output. Here, we develop PEC, electrochromic (EC), spectral (ST) triple-mode platform for sensitive visualized nonylphenol (NP). First, reasonably stepped Fermi energy level arrangement between defective TiO2 anode MoO3 cathode enables remarkable photocurrent response (Mode 1). Then, itself is widely used EC candidate, which can react with...
Heritable, type-2 von Willebrand's disease (vWD) was studied in a line of German Shorthaired Pointers (GSPs) which some members had nucleotide variant exon 28 the Willebrand factor ( VWF) gene. A polymerase chain reaction (PCR) diagnostic test for developed to establish disorder's mode inheritance and eliminate it from line. Thirty-six 49 GSPs line, 14 unrelated GSP controls, 71 dogs various breeds were tested presence nucleotide. All with vWF antigen deficiency (<70% normal) either...
For large ground-based telescopes, static and dynamic disturbances would greatly degrade the optical performance. This is especially true for wide field survey telescopes with prime focus optics. The estimation of disturbance effects on becoming increasingly important during design phase. Therefore, a telescope 2.5 m aperture 3.5 deg view studied in this research. under construction now, its first light expected at beginning 2023. method performance temporal domain active compensation to...
The weight of the primary mirror increases as aperture ground-based telescopes increases, making it more challenging to maintain positional stability and surface accuracy solid mirror. Consequently, a 2 m lightweight silicon carbide (SiC) an optimization method were proposed in this study. relationship between gravitational deformation its thickness number supports was derived based on force analysis mirror; appropriate obtained initial parameters for optimization. back structure designed...
The SiC mirror has excellent structural rigidity and thermal stability, making it widely applicable in high-power optical systems. This manuscript aims to establish a coupled analysis model of thermal-optical performance for lightweight reflector under laser irradiation. First, based on the Fourier principle, transient temperature rise is analyzed using finite element method, considering boundary conditions such as heat source convective radiation. A response established. Then, reflective...
Breast cancer remains a leading cause of mortality among women worldwide, emphasizing the urgent need for innovative prognostic tools to improve treatment strategies. Anoikis, form programmed cell death critical in preventing metastasis, plays pivotal role breast progression.
Breast cancer prognosis remains a significant challenge due to the disease's molecular heterogeneity and complexity. Accurate predictive models are critical for improving patient outcomes tailoring personalized therapies.